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Tracking the next pandemic: Avian Flu Talk

130 Cases of Swine Flu ....

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Midas View Drop Down
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    Posted: April 23 2009 at 8:40pm

U.S. Swine Flu Probe Widens as Mexico Finds Lethal Lung Illness

 

April 23 (Bloomberg) -- An urgent probe into an unusual flu outbreak that's infected seven people in the U.S. was widened after Mexico sought assistance to investigate more than 130 cases of severe respiratory disease that may be related.

Authorities in Mexico asked the Public Health Agency of Canada to help identify the cause of the lung illness linked to 13 deaths in Mexico City and four in San Luis Potosi, north of the capital. The 134 Mexican cases include five health-care workers, the Ottawa-based agency said in an e-mail today.

Tests in Mexico found patients were infected with H1N1 and type-B influenza strains and the parainfluenza virus, the agency said. In the U.S., doctors discovered a new strain of H1N1 swine influenza in patients in San Diego County and Imperial County, California, and San Antonio, Texas, the Centers for Disease Control and Prevention in Atlanta said today.

"It will be critical to determine whether or not the strains of H1N1 isolated from patients in Mexico are also swine flu," Donald Low, an infectious diseases specialist at Toronto's Mount Sinai Hospital, told ******.

Swine influenza is a respiratory disease of pigs caused by type A influenza that regularly causes outbreaks among the animals. Swine flu doesn't normally infect people, though human infections with the virus does occur and cases of human-to-human spread of swine flu viruses has been documented, according to the CDC.

To contact the reporter on this story: Jason Gale in Singapore at j.gale@bloomberg.net

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17 deaths out 134 cases is a CFR of almost 13%.   Let's hope this is not the same swine flu that appears to be spreading in the U.S., or we could be facing a pandemic significantly more severe than in recent past.   An earlier article stated that one of the seven U.S. patients was hospitalized.  One out of seven being hospitalized still doesn't sound that mild. 
 
 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: April 23 2009 at 9:15pm
Midas...There are  Not  130 cases of Swine Flu.... yet. confirmed...
 
 
 
1998
.............
 
(CIDRAP)
 
 
In 1988, an H1N1 swine flu virus was found in a previously healthy 32-year-old pregnant
 
woman who died 8 days after she was hospitalized for pneumonia, according to the CDC.
 
Four days before she got sick she had visited a swine exhibit at a county fair

 
 
 
 
................

CDC
........

 
Mexico
.....................
Kochol, Yucatan
 
 
Antibodies against influenza viruses were detected in 115 serum samples
from
 
Indigenous Mayan persons from Kochol, Yucatan.

1.7% to A/Swine/Wisconsin/238/97, and
 
79.1% to A/Swine/Minnesota/593/99.

 
(Asia has been considered as an epicenter for the generation of pandemic influenza
 
virus, and some factors are high densities of humans and animals in close contact (1).
 
In Yucatan, the backyard system is a common practice, and human and animal
 
encounters could lead to generation of novel reassortant viruses here as well.)
 
 
 
 
Texas
............
County not given

 
State of Texas gave info....'Person' ill mid October ...yr?
 
CDC said the patient was infected with a swine influenza A/H1N1 virus.
 
 
 
2005
 
Wisconsin
..................
County not given

 
 
a healthy 17-year-old boy who had mild respiratory symptoms in December 2005, 3 days after helping his brother-in-law butcher pigs.
 
 
Tested CDC
swine influenza A (H1N1) triple reassortant virus, A/Wisconsin/87/2005 H1N1.
 
 
 
 
 
 
 
2006
.........
 
 
 

Received: 12 December 2006  Accepted: 16 March 2007  Published online: 11 April 2007
 
 
 
Abstract  Influenza viruses
 
 A/Philippines/341/2004 (H1N2) and
 
 
A/Thailand/271/2005 (H1N1)

were isolated from two males, with mild influenza providing evidence of
 
sporadic human infection by contemporary swine influenza.
 
 
Both viruses were antigenically and genetically distinct from
 
influenza A (H1N1 and H1N2) viruses
 
that have circulated in the human population.
 
 
Genetic analysis of the haemagglutinin genes found these viruses to have the highest degree of similarity to the classical swine H1 viruses
 
circulating in Asia and North America.

The neuraminidase gene and the internal genes were found to be more closely
 
related to viruses circulating in European swine,
 
 
which appear to have undergone multiple reassorting events.
 
 
Although transmission of swine influenza to humans appears to be a relatively rare event, swine have been proposed as the intermediate host in the generation of potential pandemic influenza virus that may have the capacity to cause human epidemics resulting in high morbidity and mortality.
 
.........................................................................
 
 
 
 
 
 NOTE
............
 
Europe and Asian combo above...
 
 
CDC April 2009
.................................
(CIDRAP)

A new combination of genes
The viruses from the two patients are similar, and the majority of their genes, including the hemagglutinin gene, are similar to those of swine flu viruses that have circulated in US pigs since about 1999, the CDC reports. But the genes for the neuraminidase (NA) and matrix (M) proteins are similar to corresponding genes of Eurasian swine flu viruses.

 
 
People From Original April '09 CDC Report
..................................................................
 
 

California Group A
San Diego County
.................................
 
 
The first illness in the family was an 8 yr old boy who first became ill
approx. 2 weeks before his 10 yr brother.... about mid March...
 
 
On March 30th the 10 yr old  presented with  fever, cough, and vomiting on March 30, 2009, his illness was confirmed swine flu H1N1.
 
 
Then the mother  had respiratory symptoms without fever in the first few days of April.
 
 
The family flew to Texas on April 3, 2009.
 
 
The 8 yr old boy suffered a second illness with cough, fever, and
rhinorrhea on April 11, 2009.... Im Texas?
 
 
 
California Group B
 
Imperial County
.................................
 
 
March 25, 2009  a male cousin aged 13 years living in the home had influenza-like symptoms.
 
 
March 28, 2009 
9 yr old girl patient ipresented with a cough and fever of 104.3
 
Her test, swine influenza A (H1N1) virus (CDC) on April 17, 2009
 
 
April 1, 2009
The patient's brother aged 13 years had influenza-like symptoms
 
 
The 2 boys were not tested at the time of their illness.
 
 
 
 
Texas
............
San Antonio

 
 
CDC's Dr. Anne Schuchat
..................................
(REUTERS)
 
 
April 2009
 
California
.................
San Diego County
 
 
 
there's a father-daughter pair in California," Schuchat said.
 
 
April 2009
 
Texas
................
San Antonio

 two others were boys who attend the same school near San Antonio
Texas cases -- in 16-year-old boys, yesterday
..................................................................
 
 
 

April
2009
Mexico
.........
Mexico City

Epidemic
Type Unkown


Sanchez Arriaga
Volunteer
 

500 employees of the Health sector in Mexico City
 
 
 
........................
 
 
 
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