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Tracking the next pandemic: Avian Flu Talk

MRSA Superbug Thread V

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    Posted: January 14 2008 at 5:57pm
Another case of MRSA has workers at Erie Judge Dominick DiPaolo office on the lookout. A case of the drug-resistant staph infection has been reported at Judge DiPaolo's office on 1563 W. 38th Street. DiPaolos constable came down with the infection last week. DiPaolo says cleaners are scheduled to sanitize areas of his office on Wednesday... He has advised his staff to take precautions. MRSA is a resistant variation of the common bacterium Staphylococcus aureus.People with open wounds, invasive devices, and weakened immune systems are at greater risk for the infection/

Erie,PA
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Grandville schools deal with student MRSA infection case

by Sherry Kuyt
Monday January 14, 2008, 12:27 PM
Michigan

A Grandville High School student athlete was back in school on schedule last week after contracting the MRSA infection over the winter break.

According to school principal Randy Morris, the student was cleared by a medical professional before returning to school when classes resumed on Jan. 7.

MRSA, or methicillin resistant staphylococcus aureus, is a stubborn bacterial infection that has received much publicity in recent months. While many cases are mild, serious complications involving the blood, bones, or heart can sometimes develop.

Superintendent Ron Caniff sent a letter on Jan. 8 to parents of other student-athletes who might have had contact with the infected student.

"We are taking all precautions recommended by the Kent County Health Department regarding this matter," Caniff said. "Additional cleaning has been done throughout the practice facility with an appropriate germicidal cleanser."

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Wrestler with MRSA allowed to compete

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Davenport, IA

By Jon Gremmels | Sunday, January 13, 2008 | 42 comment(s)

Dan Knight is upset that one of his Bettendorf wrestlers competed against an opponent with the MRSA virus Thursday night. Davenport Assumption coach Pete Bush is upset, too, because he said had he known, he wouldn’t have let the young man wrestle.

“I would never have done that,” Bush said. “Wrestling is not so important that you put it above the kids. That’s exactly the opposite of what I want to do.”

But Knight and Bush confirmed that it did happen. An infected junior at Assumption competed Thursday and pinned a Bettendorf wrestler during the teams’ dual meet, which Bettendorf won 41-31.

“Our kids were put at risk, and I don’t think they needed to be,” Knight, Bettendorf’s head coach, said Saturday after the Bulldogs finished between champion Davenport West and third-place Assumption at the Mississippi Athletic Conference tournament. “It’s a bad deal. I’m not happy that we got put in that situation.”

Neither was Bush, who said he didn’t learn about the severity of the skin issue until Friday, which also is when Knight found out.

“A mother called me yesterday and told me what the nature of it was,” Bush said.

Skin infections are not uncommon in wrestling, and Bush said he learned Monday that his wrestler had one. Bush, who doesn’t work for Assumption except as a coach, said his policy with skin issues was to have the athlete take care of it with his parents since Bush had limited contact with the wrestler.

“Thursday, he came around and said he could wrestle. The first time I heard of MRSA was yesterday,” Bush said.

Knight said someone should have known and prevented the match. “It better not come back to bite us,” he said.

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Gays  hit by   MRSA infection spread
 A DRUG-resistant strain of potentially deadly bacteria is being transmitted among gay men during sex in the US.


http://news.scotsman.com/world/Gays--hit-by-.3671376.jp

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Superbug test case to be heard
A test case involving a woman who is suing a hospital after she contracted MRSA will be heard at the court of session in Edinburgh later.

The case is the first of its kind in UK and if successful could allow many more people to sue the NHS for infecting them with the superbug.

Elizabeth Miller, 71, contracted MRSA seven years ago while having a heart operation at Glasgow's Royal Infirmary.

Her lawyers argue ineffective hygiene standards led to her infection.

The preliminary hearing in Edinburgh will decide if the case can go ahead.

Patients have previously sued hospitals for failing to treat MRSA but because it is hard to prove how the bug was contracted, there have been no cases brought against the NHS for giving patients the bug in the first place.

However in Mrs Miller's case, swabs taken suggested she was not carrying the MRSA prior to the operation. She was one of several patients who contracted MRSA on that ward.

Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/uk_news/scotland/glasgow_and_west/7188350.stm
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Sexually-active gay men vulnerable to new, highly infectious bacteria

Sexually active gay men are many times more likely than others to acquire a new, highly antibiotic-resistant strain of the so-called MRSA bacteria widely know as the "superbug," a UCSF-led study shows.

The bacteria appear to be transmitted most easily through intimate sexual contact, but can spread through casual skin-to-skin contact or contact with contaminated surfaces. The scientists are concerned that it could soon gain ground in the general population.

The new strain of bacteria is closely related to the MRSA bacteria that have spread beyond hospital borders in recent years and caused outbreaks of severe skin and other infections. But the newly discovered microbe is resistant to many more front-line antibiotics. Both strains are technically known as MRSA USA300.

Like its less antibiotic-resistant sibling, the new multi-drug resistant microbe spreads easily through skin-to-skin contact, invading skin and tissue beneath the skin. Both strains cause abscesses and ulcerations that can progress rapidly to life-threatening infections.

"These multi-drug resistant infections often affect gay men at body sites in which skin-to-skin contact occurs during sexual activities," says Binh Diep, PhD, UCSF postdoctoral scientist at San Francisco General Hospital Medical Center and lead author of a report on the finding.

"But because the bacteria can be spread by more casual contact, we are also very concerned about a potential spread of this strain into the general population."

A good scrubbing with soap and water may be the most effective way to prevent skin-to-skin contact transmission, especially after sexual activities, Diep says.

The scientists did not address the cause of the increased risk among gay men, but suspect that sexual risk behaviors play a significant role.

The study is based on review of medical records from outpatient clinics in San Francisco and Boston as well as nine of 10 medical centers serving San Francisco.

The research appears in the January 14 early online edition of the "Annals of Internal Medicine." It will appear in the print edition February 19, along with a related editorial.

Diep considers the rapid rise in infections alarming. About one in 588 people living in San Francisco’s Castro district – a neighborhood with the highest number of gay residents in the country – are infected with the multi-drug resistant MRSA bacteria. About one in 3800 San Franciscans overall are infected – also a surprisingly high number, he says. These statistics come from the scientists’ study of MRSA samples previously collected from patients in nine medical centers serving San Francisco.

In a second part of the study based on patient medical charts, the scientists found that sexually active gay men in San Francisco are about 13 times more likely to be infected than the general population.

"The potential widespread dissemination of multi-resistant form of USA300 into the general population is alarming," he adds. The microbe is known as "multidrug-resistant, community-associated MRSA USA300." MRSA stands for methicillin-resistant Staphylococcus aureus. Until recently, MRSA bacteria were confined to hospitals, where extensive use of antibiotics has prompted highly resistant strains to evolve. The spread of multidrug resistant MRSA into communities, first reported by the UCSF team in 2006 (Lancet. 2006:367:731-9), has led to heightened concern.

The microbe studied here differs from the more familiar community-associated MRSA in that it is resistant not only to methicillin, but also resistant to a battery of normally effective, first-line antibiotics.

"Prompt diagnosis and the right treatment are crucial to prevent life-threatening infections and the spread of this bacteria to close contacts," says study author Henry Chambers, MD, UCSF professor of medicine at San Francisco General Hospital Medical Center and lead scientist of a large multi-centered clinical trial recently funded by the National Institute of Health to study treatment of community-associated MRSA infections.

The scientists conclude that research should be undertaken to explore the link between MRSA and unsafe sexual risk behaviors.

###

The study was largely funded by the Centers for Disease Control and Prevention and a Pfizer grant.

Coauthors on the paper and collaborators in the study are UCSF scientists Christopher J. Graber, MD, MPH; Francoise Perdreau-Remington, PhD; Tiffany HaiVan Phan, BA; and Heather Carleton, MPH, all at San Francisco General Hospital Medical Center.

Also: John Szumowski, MD, MPH at Beth Israel Deaconess Medical Center; Loren Miller, MD, MPH, at Harbor-UCLA Medical Center; Linda Han, MD, at State Laboratory Institute, Jamaica Plain, Mass.; Jason Chen, BA; Felice Lin, BA; Jessica Lin, BA; and George Sensabaugh, DCrim, all of the School of Public Health, UC Berkeley; Linda McDougal, MS, and Fred Tenover, PhD, both at the Centers for Disease Control and Prevention; Daniel Cohen, MD, Fenway Community Health, Boston; and Kenneth Mayer, PhD, Brown University/Miriam Hospital, Rhode Island.

UCSF is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate level education in the life sciences and health professions, and excellence in patient care.

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See the following for more information about MRSA in Schools: http://www.cdc.gov/Features/MRSAinSchools/

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Las Vegas Schools Battle MRSA

1 hour, 19 minutes ago

The Las Vegas school district is taking steps to prevent methicillin resistant staph aureus, or MRSA, infections in students and staff.

A health worker with the northern New Mexico district said that she has treated a couple of student athletes with staph infections this year.

Although none of the cases in Las Vegas are deemed serious, the infection can be life threatening. It is most often transmitted from skin to skin contact or contact with infected surfaces. MRSA is resistant to penicillin and is hard to treat.

In order to prevent further cases, the staff is frequently sanitizing a number of areas around the school including wrestling mats, school bus seats, keyboards, water fountains and even door handles.

The superintendent of Las Vegas schools said, "We wanted to make sure this is something that did not adversely affect city schools."

While the high school is taking action on its own, the school board is looking at making these efforts more permanent.

The board is expected to make treating areas with disinfectant and other measures part of its formal policy.

They will be meeting on the issue in the next couple of weeks.

Health officials say the best way to avoid an MRSA infection is by thoroughly washing your hands, covering your wounds and avoiding contact with other people's open wounds.

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GPs on alert for killer MRSA strain in nurseries, schools and the gym

Last updated at 17:52pm on 21.01.08

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Family doctors are being put on high alert for cases of a flesh-eating strain of MRSA that thrives in nurseries, classrooms and gyms.

GPs will for the first time be given detailed guidelines on how to diagnose and treat the highly infectious bug, thought to be even deadlier than the version sweeping through hospitals.

The risk is so serious that the Health Protection Agency and the British Society for Antimicrobial Chemotherapy have come together to draw up the advice, designed to stop the bug running riot across the UK as it has in the U.S.

Killer bug: GPs are being warned community-acquired MRSA can be caught in nurseries, schools and gyms

Unlike normal MRSA, communityacquired MRSA produces a flesh-eating poison that can rapidly eat away at the lungs, killing within hours.

The toxin also destroys infection-fighting white blood cells, putting fit, young, healthy people - including children and babies - at threat.

Already rampant in the U.S., communityacquired MRSA infects more than 150 Britons a year and the figure is rising by more than 30 per cent a year. Some experts also believe the true scale has not been fully reported.

Professor Mark Enright, a superbug expert from Imperial College London, said it was possible that many cases of community-acquired MRSA were going undetected, making the true toll much higher than the 159 cases reported to the HPA in 2006.

He said: "Unless GPs know what to look for, we won't know we have a community-acquired MRSA problem until it's a very big problem.

"In the U.S. it has gone from being something confined to small communities such as drug users and prisons and sports teams to become a problem in children, young adults and the general population.

"It is the most common cause of infectious disease in people going into A&E in the U.S. We don't think it is anything like as common over here but we don't really know because we are not looking for it."

So far in the UK, the bug has killed at least eight in the last three years, including a ten-year-old girl and an 18-year-old Marine. The bug can enter the bloodstream through cuts and grazes, so children are particularly at risk.

Crowded nurseries and classrooms are ideal breeding grounds, as are gyms and changing rooms where the infection can be caught simply from sharing towels.

Symptoms range from the superficial but painful, such as boils, to fatal blood poisoning.

Patients can die within 24 hours of spread to the lungs due to a form of pneumonia in which the flesh is rapidly eaten away by a poison - the Panton-Valentine Leukocidin, or PVL - produced by the bug, which also destroys white blood cells and thus the body's immune system.

Fifty per cent of victims with necrotising pneumonia die within the first 24 hours.

Community-acquired MRSA is on the march in the U.S. because it is becoming resistant to overused antibiotics.

Experts fear that could also happen in the UK. Doctors and scientists are anxious to prevent community-acquired MRSA from becoming as devastating as the version caught in hospitals.

An estimated 300,000 Britons a year pick up superbugs such as MRSA while being treated in hosbecomingpital and at least 5,000 die.

Professor Dilip Nathwani, chairman of the group putting together the guidelines, said: "We want to learn from the more typical hospital-acquired MRSA strain which has become endemic in our hospitals.

"If we improve diagnosis and prevention of this illness maybe we will slow down or prevent it from endemic in our communities.

The guidelines, due to be published in March, will advise on how to spot and treat the infection, which is often initially overlooked, with GPs mistakenly thinking telltale boils and abscesses are caused by other, less sinister infections.

Professor Nathwani said: "If someone has recurrent infections of the skin, I would encourage them to ask their GP, 'Could this be communityacquired MRSA?' Don't be shy."

Patients found to be infected could be given antibiotics, which are effective when given early, and, if necessary, admitted to hospital.

To prevent infection outside hospital, people should make sure all cuts and grazes are properly cleaned and covered.

They should also avoid sharing towels and toothbrushes and ensure any gym they use is cleaned thoroughly.

richard campbell

Richard Campbell-Smith: 18-year-old contracted community-acquired MRSA by grazing a leg on gorse while on army training in Devon

• Richard Campbell-Smith was a fit and healthy 18-year-old Marine when he caught community acquired MRSA by grazing a leg on gorse while on exercise.

He died two days after the lethal infection entered his bloodstream.

He was 28 weeks into his 32-week induction at the Commando Training Centre at Lympstone, Devon, when tragedy stuck. He and other recruits had spent the week on a rigorous training programme.

He scratched his legs while running on Woodbury Common in late 2004. He was soon struggling to walk and had to be admitted to the base's medical centre.

The infection spread rapidly, causing major organs to fail, and two days later he was found collapsed by his bed. He was taken to hospital but died shortly after arrival.


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