Click to Translate to English Click to Translate to French  Click to Translate to Spanish  Click to Translate to German  Click to Translate to Italian  Click to Translate to Japanese  Click to Translate to Chinese Simplified  Click to Translate to Korean  Click to Translate to Arabic  Click to Translate to Russian  Click to Translate to Portuguese  Click to Translate to Myanmar (Burmese)

PANDEMIC ALERT LEVEL
123456
Forum Home Forum Home > Main Forums > Latest News
  New Posts New Posts RSS Feed - H5N1 kills three in Egypt in one week
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Tracking the next pandemic: Avian Flu Talk

H5N1 kills three in Egypt in one week

 Post Reply Post Reply
Author
Message
waterboy View Drop Down
Valued Member
Valued Member


Joined: January 21 2008
Status: Offline
Points: 8170
Post Options Post Options   Thanks (0) Thanks(0)   Quote waterboy Quote  Post ReplyReply Direct Link To This Post Topic: H5N1 kills three in Egypt in one week
    Posted: December 01 2014 at 7:52am
 Egypt 

34m

Egypt's Health Ministry says 3 people have died from H5N1 bird flu in the past week, bringing death toll there to 6 - @Reuters


End of alert
Back to Top
Anything View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Anything Quote  Post ReplyReply Direct Link To This Post Posted: December 01 2014 at 12:11pm
4 cases and 3 deaths in one week, with 3 of the 4 cases from Minya governate, which has just 5 million of Egypt's 87 million population. That's quite a coincidence, given the short time frame. I really hope we're not going to be told they were all from the same family.

Some strains of H5N1 in Egypt have 2 of the 4 (or 5) genetic mutations believed to be necessary for easy human to human transmission.
Back to Top
Kilt2 View Drop Down
Adviser Group
Adviser Group
Avatar

Joined: December 17 2007
Status: Offline
Points: 7414
Post Options Post Options   Thanks (0) Thanks(0)   Quote Kilt2 Quote  Post ReplyReply Direct Link To This Post Posted: December 02 2014 at 4:19am
that puppy is ready to explode
And I looked, and behold a pale horse: and his name that sat on him was Death, and Hell followed with him.
Back to Top
arirish View Drop Down
Admin Group
Admin Group
Avatar

Joined: June 19 2013
Location: Arkansas
Status: Offline
Points: 39215
Post Options Post Options   Thanks (0) Thanks(0)   Quote arirish Quote  Post ReplyReply Direct Link To This Post Posted: December 02 2014 at 9:18am
This is a PLOS article from 2012 but worth a reread and is just as relevant today!




Egyptian H5N1 Influenza Viruses—Cause for Concern?


Published: November 15, 2012
•DOI: 10.1371/journal.ppat.1002932


http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002932
Buy more ammo!
Back to Top
carbon20 View Drop Down
Moderator
Moderator
Avatar

Joined: April 08 2006
Location: West Australia
Status: Offline
Points: 65816
Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: December 02 2014 at 1:45pm

Egypt: Another H5N1 avian flu case reported from Minya

Posted by Robert Herriman on December 2, 2014 // Leave Your Comment

Following up on reports yesterday of four new human H5N1 avian influenza (AI) cases, including three deaths in Egypt, local media reports on an additional case from Minya governorate (computer translated).

Image/CIA

Image/CIA

The report states a 25-year-old woman from one of the villages of Minya Center, was suffering from fever, cough and shortness of breath after exposure to sick and dead birds.

She was isolated on Nov. 28 and treated with Tamiflu. She is currently in stable condition.

This is the 12th H5N1 AI case reported by the Egyptian Ministry of Health in 2014, the report notes. A 13th case was reported by the Ministry of Health of Beheira governorate earlier this year.

HPAI H5N1 virus can infect the respiratory tract of humans. When people develop illness from HPAI H5N1 virus infection, severe respiratory illness (e.g. pneumonia and respiratory failure) and death may occur, according to the Centers for Disease Controland Prevention.

The majority of HPAI H5N1 cases have occurred among children and adults younger than 40 years old. Mortality has been highest in people aged 10-19 years old and young adults. Most human HPAI H5N1 cases have presented late in their illness for medical care and have been hospitalized with severe respiratory disease. However, some clinically mild HPAI H5N1 cases have been reported, especially in children.

In the majority of cases, the person got HPAI H5N1 virus infection after direct or close contact with sick or dead infected poultry.

Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖

Marcus Aurelius
Back to Top
Anything View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Anything Quote  Post ReplyReply Direct Link To This Post Posted: December 03 2014 at 10:32am
Another death from H5N1, again in Minya, this time a 26 year old man. It's beginning to look like there's a strain in the region which transmits more easily from birds to humans than other strains. Question is, does that mean it transmits more easily between people?

http://www.reuters.com/article/2014/12/03/us-birdflu-egypt-idUSKCN0JH1V520141203
Back to Top
Kay View Drop Down
Adviser Group
Adviser Group
Avatar

Joined: October 22 2014
Location: OHIO
Status: Offline
Points: 7205
Post Options Post Options   Thanks (0) Thanks(0)   Quote Kay Quote  Post ReplyReply Direct Link To This Post Posted: December 03 2014 at 8:21pm
http://www.reuters.com/article/2014/12/03/us-birdflu-egypt-idUSKCN0JH1V520141203
 

Egyptian dies of H5N1 bird flu, bringing total to seven: health ministry

Back to Top
Kay View Drop Down
Adviser Group
Adviser Group
Avatar

Joined: October 22 2014
Location: OHIO
Status: Offline
Points: 7205
Post Options Post Options   Thanks (0) Thanks(0)   Quote Kay Quote  Post ReplyReply Direct Link To This Post Posted: December 03 2014 at 8:33pm
http://www.recombinomics.com/News/12031402/H5N1_Egypt_7.html
 
 
The clustering in time and space raises concerns that the H5N1 has changed.  Human sequences since 2009 have belonged to a sub-clade with a deletion at position 133 and have structural similarities with seasonal H1N1.
Back to Top
carbon20 View Drop Down
Moderator
Moderator
Avatar

Joined: April 08 2006
Location: West Australia
Status: Offline
Points: 65816
Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: December 04 2014 at 5:11am
Audio:Feb18 Mar18 Mar31 Apr15 RSS Feed twitter News Now                         
Live feed of underlying pandemic map data here
Commentary


Fixing of 133del In Human H5N1 In Egypt 
Recombinomics Commentary 22:22
May 6, 2010


NAMRU-3 has recently released HA and NA sequences from recent H5N1 cases in Egypt (11 from 2009 and 12 from 2010).  All 23 HA sequences had 133del (3 BP deletion using H3 numbering), indicating the deletion is becoming fixed in human H5N1 in Egypt.  An earlierpaper, “Characterization of conserved properties of hemagglutinin of H5N1 and human influenza viruses: possible consequences for therapy and infection control” had noted similarities between H5N1and seasonal H1N1, raising concerns of increased human transmission (H2H) of H5N1 with 133del.  This concern was increased by the recent paper describing the detection of H5N1 in donkeys and serological evidence of widespread H5N1 antibodies in donkeys.

Concerns of human to human H5N1 transmission in Egypt were raised when mild cases in children were reported in the spring of 2007.  Several had the 3 BP deletion and sequences were closely related.  There children had a mild course, which did not include pneumonia.

In early 2009, mild cases were reported in toddlers.  The large number of cases reduced the case fatality rate for H5N1 in 2009 to approximately 10%.  The sequences from these toddlers also had 133del, which was followed by the most recent 23 sequences which were from the summer of 2009 to March 31, 2010.

Poultry H5N1 sequences collected in the past year were more diverse and included vaccine resistant H5N1.  However, all human sequences contained 125del and many of the 2010 sequences were closely related to each other raising additional concerns that H5N1 is transmitting H2H.

Since Egypt does not H5N1 test patients who do not have a poultry contact, the full extent of H5N1 remains largely unknown.  Serological testing has been discussed for over a year.  During that time a serological survey on donkeys was conducted, which showed widespread antibodies in donkey serum.  

Results for a comparable test in humans, using a 133del H5N1 target is long overdue.

Media Links

Recombinomics Presentations

Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖

Marcus Aurelius
Back to Top
Anything View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Anything Quote  Post ReplyReply Direct Link To This Post Posted: December 04 2014 at 8:31am
Yet another confirmed case, a 33 year old male, but not from Minya. 

http://outbreaknewstoday.com/more-h5n1-bird-flu-cases-in-egypt-39888/
Back to Top
arirish View Drop Down
Admin Group
Admin Group
Avatar

Joined: June 19 2013
Location: Arkansas
Status: Offline
Points: 39215
Post Options Post Options   Thanks (0) Thanks(0)   Quote arirish Quote  Post ReplyReply Direct Link To This Post Posted: December 04 2014 at 9:45am
More H5N1 bird flu cases in Egypt

Posted by Robert Herriman on December 4, 2014 // Leave Your Comment

The number of human H5N1 avian influenza cases continue to climb in Egypt this month as the Egyptian Health ministry announced the ninth and tenth case of the dangerous disease in a press release today (computer translated).

The two cases are as follows: A 26-year-old man from a village in Mallawi district of Minya who was suffering from fever, cough and shortness of breath after exposure to birds. He was isolated in the hospital on Nov. 30 and died on Dec. 1.

The second case is a 33-year-old from Parit Buntar Suhag governorate who and was suffering from fever, cough and shortness of breath and was isolated in a private hospital. He is currently on a ventilator and in stable condition.

The addition of these two cases bring the number reported by the Egyptian MOH in 2014 to 14. A 15th case was reported by the Ministry of Health of Beheira governorate earlier this year.

According to the WHO, the primary risk factor for human infection with the virus appears to be direct or indirect exposure to infected live or dead poultry or contaminated environments.

They go on to say there is no evidence to suggest that the H5N1 virus can be transmitted to humans through properly prepared poultry or eggs. A few human cases have been linked to consumption of dishes made of raw, contaminated poultry blood. However, slaughter, defeathering, handling carcasses of infected poultry, and preparing poultry for consumption, especially in household settings, are likely to be risk factors.

For more infectious disease news and information, visit and “like” the Infectious Disease News
http://outbreaknewstoday.com/more-h5n1-bird-flu-cases-in-egypt-39888/
Buy more ammo!
Back to Top
arirish View Drop Down
Admin Group
Admin Group
Avatar

Joined: June 19 2013
Location: Arkansas
Status: Offline
Points: 39215
Post Options Post Options   Thanks (0) Thanks(0)   Quote arirish Quote  Post ReplyReply Direct Link To This Post Posted: December 04 2014 at 9:51am

Egypt on alert over bird flu


Concern that its Dh11b poultry industry faces the prospect of collapse
By Ramadan Al Sherbini Correspondent
Published: 13:30 December 3, 2014


Cairo: Egyptian health authorities have maximised their measures to combat bird flu (H5N1), after the virus killed six people this year in this country of around 87 million people.


Health Minister Dr Adel Al Adwai on Wednesday held a crisis meeting with an ad-hoc committee to discuss efforts to combat the virus amid expectations of a rise in infections this winter.


The Health Ministry called on poultry breeders to observe precautionary measures while dealing with birds in the winter when the avian virus usually spreads. The ministry has said it has enough stocks of Tamiflu used to treat the virus.


“A relative increase is expected in the number of the recorded H5N1 cases this year especially as the virus has become endemic in Egypt,” said Dr Amr Qandil, an aide to the health minister. “The Higher Commission on Bird Flu meets on a daily basis to monitor the situation.”


Residents of Egypt’s rural areas traditionally rear birds inside houses to meet their needs of meat and eggs, raising authorities’ concerns about a wider spread of the virus.


Head of the Veterinarians’ Association, Sami Taha, warned in press remarks, that Egypt’s Dh11 billion poultry industry faces the prospect of collapse unless more effective steps are taken to contain the epidemic.


Around one million of the nation’s workforce are employed in this industry, according to official figures.


Egypt has identified this year 12 cases of H5N1 infections, six of them fatal. A total of 66 people have died of bird flu in the country since 2006, according to health authorities.

http://gulfnews.com/news/region/egypt/egypt-on-alert-over-bird-flu-1.1421538
Buy more ammo!
Back to Top
Anything View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Anything Quote  Post ReplyReply Direct Link To This Post Posted: December 04 2014 at 10:58am
What I find a bit disturbing is that the Egyptian authorities only test for H5N1, if there is evidence of contact with poultry. H to H transmission is probably a long shot, but it's still possible such cases are being missed
Back to Top
carbon20 View Drop Down
Moderator
Moderator
Avatar

Joined: April 08 2006
Location: West Australia
Status: Offline
Points: 65816
Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: December 04 2014 at 1:52pm
Originally posted by Anything Anything wrote:

What I find a bit disturbing is that the Egyptian authorities only test for H5N1, if there is evidence of contact with poultry. H to H transmission is probably a long shot, but it's still possible such cases are being missed

me too i just cant get my head around this one ..........very scary.......
Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖

Marcus Aurelius
Back to Top
jacksdad View Drop Down
Executive Admin
Executive Admin
Avatar

Joined: September 08 2007
Location: San Diego
Status: Offline
Points: 47251
Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: December 05 2014 at 12:26am
I'm not sure if it's been determined that there is such a thing as a mild or asymptomatic case of H5N1 - it always seems to cause severe respiratory symptoms, and with Egypt's history I'm sure it would be hard for them to miss a case even if they weren't testing. H2H would probably be picked up pretty quickly, especially if the virus follows the pattern we've seen so far and infects within families. I don't think there's much chance of it spreading unnoticed.
"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
Back to Top
 Post Reply Post Reply
  Share Topic   

Forum Jump Forum Permissions View Drop Down