This is from a veterinary pathologist. They had retweet turned off so I scrubbed out their info.
Tracking the next pandemic: Avian Flu Talk |
H5N1 pandemic |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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Posted: March 31 2024 at 12:07am |
DJ, I hate "fear-porn" but I do believe in "early warning" ! From a history perspective lots of "bad things" may have been prevented if "we opened our eyes in time" ! Wishfull thinking and "saving profits "the economy" may end up very destructive because governments fail to take action in time ! CoViD-19/SARS-2 -like SARS-1 in 2003- could have been stopped before it did become a pandemic ! [url]https://en.wikipedia.org/wiki/COVID-19_lockdown_in_China[/url] or https://en.wikipedia.org/wiki/COVID-19_lockdown_in_China ; On 23 January 2020, the central government of China imposed a lockdown in Wuhan and other cities in Hubei in an effort to quarantine the center of an outbreak of COVID-19; this action was commonly referred to as the Wuhan lockdown (Chinese: 武汉封城; pinyin: Wǔhàn fēng chéng). The World Health Organization (WHO), although stating that it was beyond its own guidelines, commended the move, calling it "unprecedented in public health history".[2] yet most of the world did NOT take action in time...M.Koopmans-top virologists; NL has no need to worry because there are no direct flights from Wuhan-China to NL ...(was it APRIL !!!??? 2020 she made that claim ???) ----- H5N1 was a global problem in 2022, 2023 most in birds all over the planet being infected with High Pathogenic Avian Influenza HPAI A-H5N1... In 2023 Argentina reported spread of H5N1 in sealions, from sealion to sealion...Lots of mammals did test positive for H5N1-very likely most of them after eating death infected birds or contact with infected bird droppings... March 2024 did see H5N1 spreading in US cattle...from cow-to-cow... DJ, AI is "far from perfect" however the scenario sounds very realistic; So in the r/H5N1_AvianFlu community, one of the users asked Claude Opus, a generative AI model, what would happen in the worst case scenario. This is what Claude had to say. Thoughts? Should we trust an AI generative model or no?This is how the prompt went… Human transmission of the mutated HPAI virus, which we'll call the "Omega Strain," occurs about 2 months after the initial detection in dairy cows. Here's how it could unfold: Despite biosecurity measures, the virus continues to spread rapidly among cattle herds across the country. The high mutation rate of the virus leads to a concerning development - a novel strain emerges that has acquired the ability to efficiently spread from cattle to humans and then between humans. The first human cases are reported among dairy farm workers who had close contact with infected cows. They experience severe flu-like symptoms that quickly progress to acute respiratory distress syndrome (ARDS) and multi-organ failure. The case fatality rate in this initial cluster is a frightening 60%. Human-to-human transmission is soon confirmed as family members and healthcare workers treating the patients also fall ill. The virus spreads rapidly in healthcare settings and communities, overwhelming hospitals in affected areas. Within weeks, the Omega Strain has spread to all major U.S. cities and begins to appear in other countries. The global medical community scrambles to understand the virus and develop treatments, but its high mutation rate makes it a challenging target. In this scenario, the Omega Strain could have a case fatality rate of around 35-40% overall, higher in older adults and those with underlying health conditions. It would be particularly devastating in densely populated urban areas and countries with weaker health systems. By the 6-month mark, the worldwide death toll could reach into the tens of millions as countries struggle to control the spread and treat the sick. The pandemic would cause massive social and economic disruption on a global scale. Is this really what will happen, or should we just wait and see? Should we always trust AI? I have a grandfather myself, and he’s in his 80’s, and I do not want him to be amongst this group as he’s coming to live with us. End of part 1 |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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part 2; DJ, When one looks at how "politics" totally failed and made CoViD-19 into a pandemic "saving the economy" I do not doubt "present politics" will do "all they can" to also send H5N1 on a world tour.... [url]https://twitter.com/ejustin46/status/1773968684668637277[/url] or https://twitter.com/ejustin46/status/1773968684668637277 Among Others; 8) 𝗕 𝗰𝗲𝗹𝗹𝘀 𝗱𝘆𝘀𝗿𝗲𝗴𝘂𝗹𝗮𝘁𝗶𝗼𝗻 B cells is of such importance, particularly in the infection - reinfection process, that we will return in a mega-thread especially dedicated to this subject. Thanks for reading DJ link to a thread explaining how CoViD-19 destroys immunity...so; the doors are wide open for H5N1 ! [url]https://twitter.com/siamosolocani/status/1773056496223305987[/url] or https://twitter.com/siamosolocani/status/1773056496223305987 ; This is a great study coming from Nigeria finding Sars1 and Sars2 crossreactives antibodies between 2020-22 in wild/domestic animals. I m not a virologist but it seems very well done. Congrats to authors:
Et al DJ....CoViD is NOT over...it may even be SARS-1 and SARS-2 "did meet and mix"...so we may see another-new-CoViD pandemic...Mixed with H5N1 we could end up with "Flu-Rona"...only the name is "nice"... [url]https://twitter.com/ejustin46[/url] or https://twitter.com/ejustin46 lots of info... Wars and climate collapse are "perfect feeding grounds" for pandemics... end of part 2 |
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We cannot solve our problems with the same thinking we used when we created them.
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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part 3; [url]https://www.reddit.com/r/Virology/comments/1br655j/so_in_the_rh5n1_avianflu_community_one_of_the/[/url] or https://www.reddit.com/r/Virology/comments/1br655j/so_in_the_rh5n1_avianflu_community_one_of_the/ has comments-maybe interesting views, Also DJ-I am NOT any kind of expert...I am NOT writing any "science"...just trying to make my mind up.... -We will miss 95-99% of H5N1 cases in animals...maybe even more... -Here in NL sometimes the number of dead birds from H5N1 was that large only those bodies near urban area's were destroyed.. -So in many places wild animals did eat H5N1 infected birds... -Bird droppings also may have the H5N1 virus... -Dried infected droppings could result in virus spread by the wind..."viral-dust"... DJ-Of course there are LOTS of ways to stop getting infected! Masks do help ! Ventilation lowers viral loads ! We could increase testing for H5N1 in mammals...problem is we are NOT doing it ! -Avoiding panic -Saving the economy... DJ-You NEED an economy to have public healthcare...but you also need to be aware of risks, find a balance and a will to face problems ! Part of a comment;
Cows are likely not going to be the source for this type of spillover.
Historically HPAI H5 is at about a 60% CFR, so this is probably where it's pulling the number from. This changes a lot with many factors, but a transmissible cluster at this CFR is highly unlikely.
We have antivirals and vaccines against H5, so this isn't the case.
That would be an order of magnitude higher than anything seen in transmissible flu settings. It's pulling from case data, but there's a pretty significant underreporting factor that moderates that. Still even 10 fold less would be a nightmarish virus.
Anything that deadly would bring the world to a halt worse than we saw with COVID. I don't think we'd ever seen numbers like this in 6 months. That's too Hollywood. DJ, H5N1 has now been detected to be spreading between sealions, cows....we may have missed a lot of mammal-to-mammal spread... End of part 3... |
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We cannot solve our problems with the same thinking we used when we created them.
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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part 4, Another comment; Pigs are the common source of true pandemic leap from livestock to human, so maybe general farmer? But a slaughterhouse is a much more likely jumping off point, lots of blood, very close quarters, animals from all over you get the picture. As for CFR, HPAI has a CFR of 50%+ when its host is an animal because of several factors, but no flu in history that’s spreading H2H rapidly has even approached 50%, it would simply burn itself out. This is basically virology version of the FAFO chart, as CFR goes up, R0 tends to go down, so 50% CFR leading to a global pandemic like COVID is statistically and biologically impossible. You’re more likely case is “Slaughterhouse worked in Iowa reports to local health clinic and dies from flu like symptoms 5 days later, CDC receives a flu sample indicating H5N1 has jumped to humans. Several other members of his factory have symptoms and the doctor who treated him has become sick as well, flash forward 6 months and CFR of 1.1% in elderly and young with a CFR of .3% in young(we must take into account immunological imprinting and almost everyone 60 and younger have been exposed to H1N1 since birth so we get a slight leg up plus our good immune system). This will undoubtedly be a cataclysmic loss of life but it is not the earth ending pandemic of a 50% CFR - Hope you are right, but HPAI has been causing havoc among migratory birds, poultry and mammals since the 90's and possibly even earlier, even though it has a high CFR. Also, pigs were thought to be the main organism of concern as a mixing vessel, though recent studies suggest a lot more organisms are potential mixing vessels, such as dogs and felines. I think the first human transmissible HPAI will he due to poultry-human contact, due to this clade's capability to spill over without a mixing vessels, as did happen to seals, cats, cows, pigs and other mammals.. DJ, H5N1 in US cows did NOT kill those -still very limited number of- cows...Cow-to-cow spread of H5N1 has to be seen as part of a much larger global trend; -H5N1 is getting very widespread both in areaś and "hosts" -CoViD may decrease immunity -Politics do not seem to have public health as a high priority -Lots of wars/crises around the globe... [url]https://flutrackers.com/forum/forum/the-pandemic-discussion-forum/987828-discussion-thread-hpai-in-us-dairy-cows-march-24?view=stream[/url] or https://flutrackers.com/forum/forum/the-pandemic-discussion-forum/987828-discussion-thread-hpai-in-us-dairy-cows-march-24?view=stream (a.o. trying to get some basic idea). I do not know what assay is being used to test cattle for H5N1 at this time but from 2008: "...Our findings show that HPAIV (H5N1) has the potential to infect bovine calves, at least after high-titer intranasal inoculation, and that conventional HI tests may underestimate such infections....The NP-ELISA is currently the assay of choice for the evaluation of bovine serum, and the VN test should be used for confirmation..." Emerg Infect Dis. 2008 Jul; 14 - Experimental Infection of Cattle with Highly Pathogenic Avian Influenza Virus (H5N1) DJ...again...pointing to higher risk... end of part 4 |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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part 5, - -DJ...very likely "limited testing" to "limit damage"....So farm workers, farm cats/dogs may NOT be tested... [url]https://www.wormsandgermsblog.com/2024/03/articles/animals/other-animals/avian-flu-in-cattlewhat-to-be-concerned-about-and-what-to-not-freak-out-about/[/url] or https://www.wormsandgermsblog.com/2024/03/articles/animals/other-animals/avian-flu-in-cattlewhat-to-be-concerned-about-and-what-to-not-freak-out-about/ ; By Scott Weese on POSTED IN OTHER ANIMALS DJ...we do not know if 99,99% of H5N1 spread has been in birds...Very likely -so far- over 95% of H5N1 cases will have been in birds...However cow-to-cow, sealion-to-sealion spread IS alarming.... And again...the H5N1 spread has to be seen in the context of decrease of immunity...More H5N1 in mammals will result in new variants better able to spread in mammals (including humans)... High Case Fatality Ratio MAY !!!! result in lower R0/spread...however history may indicate pandemics can bring high CFR and high R0....(that is what makes them bad news...). Enough for now... |
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We cannot solve our problems with the same thinking we used when we created them.
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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DJ, In a very optimistic scenario H5N1 in US cows are limited, stop spreading and will be over, "old news" in a few months...Case-Fatality-Ratio remain 0...Cows feel "unwell" produce less milk...Most of the damage is economic; milk can 't be sold...cow-meat may not be sold as well... The bigger picture is H5N1 has been seen in lots of mammals [url]https://en.wikipedia.org/wiki/List_of_mammals_that_can_get_H5N1[/url] or https://en.wikipedia.org/wiki/List_of_mammals_that_can_get_H5N1 (the wiki-list will be updated)... Spread from cow-to-cow, sealion-to-sealion is a "major worry"....Also H5N1 can mix with other types of flu-result in a much higher risk type of flu... link; [url]https://jech.bmj.com/content/62/6/555.abstract[/url] or https://jech.bmj.com/content/62/6/555.abstract ; AbstractBackground: Accurate estimation of the case-fatality (CF) rate, or the proportion of cases that die, is central to pandemic planning. While estimates of CF rates for past influenza pandemics have ranged from about 0.1% (1957 and 1968 pandemics) to 2.5% (1918 pandemic), the official World Health Organization estimate for the current outbreak of H5N1 avian influenza to date is around 60%. Methods and results: The official estimate of the H5N1 CF rate has been described by some as an over-estimate, with little relevance to the rate that would be encountered under pandemic conditions. The reasons for such opinions are typically: (i) numerous undetected asymptomatic/mild cases, (ii) under-reporting of cases by some countries for economic or other reasons, and (iii) an expected decrease in virulence if and when the virus becomes widely transmitted in humans. Neither current data nor current literature, however, adequately supports these scenarios. While the real H5N1 CF rate could be lower than the current estimate of 60%, it is unlikely that it will be at the 0.1–0.4% level currently embraced by many pandemic plans. We suggest that, based on surveillance and seroprevalence studies conducted in several countries, the real H5N1 CF rate should be closer to 14–33%. Conclusions: Clearly, if such a CF rate were to be sustained in a pandemic, H5N1 would present a truly dreadful scenario. A concerted and dedicated effort by the international community to avert a pandemic through combating avian influenza in animals and humans in affected countries needs to be a global priority. DJ, CFR is "just one statistic", long term damage (like with CoViD, Q-fever, Lyme etc.) has to be another major worry... ALSO; CoViD is NOT over ! Co-infections of H5N1 with CoViD, Mpox etc. will worsen the outcome of major spread of H5N1 ! |
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We cannot solve our problems with the same thinking we used when we created them.
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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Human case in Texas: - CDC Newsroom Releases: Highly Pathogenic Avian Influenza A (H5N1) Virus Infection Reported in a Person in the U.S. CDC’s Risk Assessment for the General Public Remains Low Press Release For Immediate Release: Monday, April 1, 2024 ... - |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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[url]https://afludiary.blogspot.com/2024/04/cdc-statement-risk-assessment-on-texas.html[/url] or https://afludiary.blogspot.com/2024/04/cdc-statement-risk-assessment-on-texas.html ; The CDC has weighed in, via an emailed press release (I'll update a link when I find one), on the Texas H5N1 case announced about 45 minutes ago by the DSHS. For now, this appears to be an isolated case, although monitoring and testing of close contacts is undoubtedly underway.
-- This is the second person reported to have tested positive for influenza A(H5N1) viruses in the United States. A previous human case occurred in 2022 in Colorado. Human infections with avian influenza A viruses, including A(H5N1) viruses, are uncommon but have occurred sporadically worldwide. CDC has been monitoring for illness among people exposed to H5 virus-infected birds since outbreaks were first detected in U.S. wild birds and poultry in late 2021. Human illnesses with H5N1 bird flu have ranged from mild (e.g., eye infection, upper respiratory symptoms) to severe illness (e.g., pneumonia) that have resulted in death in other countries. -- Preliminary analysis of A(H5N1) viruses has not found changes that would make these viruses resistant to current FDA-approved flu antiviral medications, so these are believed to be effective against these viruses. Candidate vaccine viruses (CVVs) developed against related clade 2.3.4.4b viruses are available for vaccine manufacturing if necessary and preliminary analysis indicates that they may provide reasonable protection against H5N1 influenza viruses. Seasonal flu vaccines do not provide protection against these viruses. Analysis of virus samples is ongoing. DJ, H5N1 may cause no or only mild symptoms-so easy to miss... -[url]https://www.mediarunsearch.co.uk/two-people-have-been-diagnosed-with-bird-flu-in-england/[/url] or https://www.mediarunsearch.co.uk/two-people-have-been-diagnosed-with-bird-flu-in-england/ Two people have been diagnosed with bird flu in EnglandCAMELIA KIRK APRIL 1, 2024 Two people have been diagnosed with bird flu in England, according to the UK Health Security Agency (UKHSA), on Tuesday (16/5). The infected people are poultry farmers who work on a farm where cases of bird flu infection among animals have already been confirmed. They are infected with influenza A (H5) virus, but have no symptoms of illness. Confirmation was made through an asymptomatic testing program for people who had contact with infected birds. [url]https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Human_infections[/url] or https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Human_infections ; Human infections[edit]As of March 2024, the WHO reported a total of 888 confirmed human cases which resulted in the deaths of 463 people since 2003.[5] DJ a list at [url]https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Transmission_and_host_range[/url] or https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Transmission_and_host_range ; Confirmed human cases and mortality rate of avian influenza (H5N1) 2003–2024 DJ, since a lot of mild/asymptomatic cases will be missed the CFR will be much lower-however co-infections may push up the CFR |
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We cannot solve our problems with the same thinking we used when we created them.
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roni3470
Adviser Group Joined: August 30 2006 Location: Colorado Status: Offline Points: 5390 |
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can we talk about how seriously you all are taking this. it seems huge to me and I am planning on stocking up on more food and water. What do you guys think? We live rural but it has grown so also wondering when we should pack up and go to our mountain cabin! what will be the signs that make you do that/!?! |
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NOW is the Season to Know
that Everything you Do is Sacred |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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roni3470, my non expert-far from perfect-view; -War situation = very bad, getting worse for now... -Climate situation = very bad also worsening... -Pandemic situation = bad On H5N1, at least three human cases reported april 1; 1 US-Texas and 2 from UK...all mild. Very likely an increase of testing will increase findings. My view; new types of the H5N1 virus may have seen some mutations resulting in more spread in mammals. So cows, humans may run more risks. It may be -for now- very hard to be 100% certain of spread from sealion-to-sealion, cow-to-cow...however from a risk management view one should not wait for such proof. [url]https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Transmission_and_host_range[/url] or https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Transmission_and_host_range has 888 human cases testing positive for H5N1 since 2003. Both Cambodia and Vietnam did report a human death linked to H5N1 this year. Given the very limited number of detected human cases the Case Fatality Ratio (CFR) may give an overestimation. Real CFR may also differ from the variant of H5N1. Some forms of H5N1 could have a CFR of 0....not much worse than a cold... - The problem is in recombinations, coinfections, aerosol spread etc. Lots of other diseases (from measles, dengue to Mpox, CoViD) may be getting worse. Signs and symptoms of a bird flu infection Fever/chills (temp. of 100°F [37.8°C] or greater) Cough Sore throat Runny or stuffy nose Headaches Fatigue Eye redness (conjunctivitis) Difficulty breathing/shortness of breath Diarrhea Nausea Vomiting Seizures https://dshs.texas.gov/news-alerts/health-alert-first-case-novel-influenza-h5n1-texas-march-2024 A lot of these symptoms can be indicators for lots of diseases...even most polio-cases may have some of the same symptoms... If I would use a "color-scale" for "mixed dangers" BLACK may be the worst...we may however be moving from RED to PURPLE...just one step away from BLACK... Maybe another remark; "moving into a safe place" to early may limit safety of that "safe place" (using reserves etc.). Timing in a crisis matters-but timing NEVER can be 100% perfect. Just my view...from an urban area in NL...if you are in a position with "lots of safe places" it may influence your view. |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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DJ, [url]https://www.thailandmedical.news/news/breaking-america-might-emerge-as-the-epicenter-for-a-global-h5n1-outbreak-after-the-avian-virus-infecting-dairy-cows-jumps-to-a-human-in-texas[/url] or https://www.thailandmedical.news/news/breaking-america-might-emerge-as-the-epicenter-for-a-global-h5n1-outbreak-after-the-avian-virus-infecting-dairy-cows-jumps-to-a-human-in-texas TMN I can not copy from this site. Often it has links to sources. The info is NOT always "perfect"..but it may be "thought provoking"...Some claims in the article; -US department for Agriculture estimate 2,7 million US cows may have the H5N1 virus (a source for that would be welcome !) -Texas maje got H5N1 from an infected cow. Cow-to-cow spread and "just one or two mutations away" from jumping/spreading in humans. -CoViD19 limited immunity resulting in farm workers more vulnerable to H5N1. -End of april could see start of H2H spread - some US health agencies may think possible... -In the US increase of surveilance for H5N1 -Animal health, public health, virologists etc. need to wotk together. DJ-I wonder how TMN came with 2,7 million US cows may have H5N1. [url]https://www.science.org/content/article/bird-flu-discovered-u-s-dairy-cows-disturbing[/url] or https://www.science.org/content/article/bird-flu-discovered-u-s-dairy-cows-disturbing -others did not mention any numbers... It may be to early to make claims on H5N1 spread in US cows. It could be "limited" with bird droppings in -just a few- areas "easy" spreading in cows. Maybe just one cow-to-cow infection ???? We need to know much more...will learn a lot this week-also from the UK, other places...[url]https://www.mediarunsearch.co.uk/two-people-have-been-diagnosed-with-bird-flu-in-england/[/url] or https://www.mediarunsearch.co.uk/two-people-have-been-diagnosed-with-bird-flu-in-england/ ; The infected people are poultry farmers who work on a farm where cases of bird flu infection among animals have already been confirmed. So three human cases in "the news" on one day (april 1) all three mild/no symptoms...all three in contact with infected animals. |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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[url]https://www.wormsandgermsblog.com/2024/04/articles/animals/other-animals/human-h5n1-likely-linked-to-cattle/[/url] or https://www.wormsandgermsblog.com/2024/04/articles/animals/other-animals/human-h5n1-likely-linked-to-cattle/ (from Canada...so why not mention the two UK cases ?) Human H5N1 likely linked to cattleBy Scott Weese on POSTED IN OTHER ANIMALS DJ, I put all of the (good) article to put things in perspective...YES there is a problem, NO we are -not yet- in any kind of human H5N1 pandemic ! Both the US -limited number of- cows as the latest three US/UK human H5N1 infections are (very) mild. More testing will increase "statistics" but make control better ! From that view...more H5N1 infections getting reported is "good news"; at least we are testing for it ! |
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We cannot solve our problems with the same thinking we used when we created them.
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Dutch Josh
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On [url]https://twitter.com/dgurdasani1[/url] or https://twitter.com/dgurdasani1 ; Clinical epidemiology, machine learning, NLP, global health. Intersectional feminist. she/her. Also on @dgurdasani1@mastodon.world .bsky.social DJ, so epidemiologists wondering why cows testing positive for H5N1 seem not to be seperated... On [url]https://twitter.com/MarionKoopmans[/url] or https://twitter.com/MarionKoopmans ; Head of Viroscience Department , WHO collaborating centre EID Rotterdam, The Netherlandserasmusmc.nl/en/research/de… DJ...glasses/eye protection may limit infection risks... [url]https://twitter.com/HmpxvT/status/1774873864603918454[/url] or https://twitter.com/HmpxvT/status/1774873864603918454 ; "Clinicians should consider the possibility of H5N1 virus infection in persons showing signs or symptoms of acute respiratory illness who have relevant exposure history" Case definitions and epidemiologic Criteria for testing can be seen below. and DJ, we failed to stop CoViD-19/SARS becoming a pandemic-action in january 2020 could have prevented the pandemic... So now we have to do ALL WE CAN !!! to contain further spread of H5N1 in mammals/humans... testing may already be a major problem...spreading info is "just the groundwork"... [url]https://twitter.com/1goodtern/status/1775046451040510260[/url] or https://twitter.com/1goodtern/status/1775046451040510260 underlining political failure can turn any virus into a pandemic... DJ,the major problem is H5N1 has been spreading in mammals -eating infected birds- for over two years...Millions of mammals may have had H5N1-infection...most likely mild in most cases...but it does increase mutations/variants...We simply may not know a lot of mammal-to-mammal (a symptomatic) spread... |
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We cannot solve our problems with the same thinking we used when we created them.
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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DJ, H5N1 also in Texas cats; - [url]https://afludiary.blogspot.com/2024/04/usda-confirms-avian-flu-in-new-mexico.html[/url] or https://afludiary.blogspot.com/2024/04/usda-confirms-avian-flu-in-new-mexico.html ; Although New Mexico has been mentioned now for at least a week as having HPAI presumptive positive cattle, the verification process by the National Veterinary Services Laboratories (NVSL) - which is undoubtedly dealing with a large number of samples - can take some time.
It seems likely that additional infected herds will be announced in the days and weeks ahead. While the only positive tests have come thus far from symptomatic dairy cows, it isn't clear how aggressively non-symptomatic cattle are being tested (or if the capacity even exists to do so on a large scale). The USDA's FAQ, issued on March 29th (see excerpt below) makes it pretty clear they are concentrating primarily on testing symptomatic cattle. - Federal and state agencies continue to conduct additional testing in swabs from sick animals and in unpasteurized clinical milk samples from sick animals, as well as viral genome sequencing, to assess whether HPAI or another unrelated disease may be underlying any symptoms. - While hopefully only symptomatic dairy cows are carrying the HPAI virus, until wider testing is conducted, that assumes facts that are not yet in evidence. And even if non-dairy cows aren't being infected today, that provides no guarantees for the future.
Which means we don't really know how long the virus has been infecting cattle, or how widespread it has become. In the same vein, yesterday's announced (mild) human infection would likely have gone undiagnosed if the alert hadn't been issued a week ago. In a few southern states some county and state fairs are already underway, with agricultural exhibits of both cattle and swine being well attended events. Those numbers will increase over the summer and fall. While most fairs require the screening and barring of `sick animals' from exhibition, over the years we've learned that many pigs may be infected asymptomatically (see EID Journal: Flu In Healthy-Looking Pigs and Transmission Of Swine H3N2 To Humans At Agricultural Exhibits - Michigan & Ohio 2016). It is unknown if HPAI in exhibition cattle will pose a similar risk, but the possibility can't be ignored. It is also reasonable that if cattle and goats are being infected via wild birds, that pigs may be at risk as well.
Otherwise we risk finding out the hard way that HPAI is more entrenched in livestock than we think. DJ...recommendations...country/state fairs with mixing of cows, sheep, pigs, humans.... Did we learn anything ????? DJ, H5N1 may have killed hundreds of millions of birds all over the planet...most of those birds got eaten by mammals...so H5N1 got widespread in mammals via infected birds... Why do we only "wake up" when humans test positive for H5N1 ? [url]https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Human_infections[/url] or https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Human_infections [url]https://en.wikipedia.org/wiki/2020%E2%80%932024_H5N1_outbreak[/url] or https://en.wikipedia.org/wiki/2020%E2%80%932024_H5N1_outbreak [url]https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Transmission_and_host_range[/url] or https://en.wikipedia.org/wiki/Influenza_A_virus_subtype_H5N1#Transmission_and_host_range 889 human cases-still missing the 2 UK april-cases... What to do ? -Stay informed ! -Masks + eye protection (at least in higher risk area/farm) -Most of the spread may be without (severe) symptoms..."it could look like hayfever".... -Take risks serious !!!! [url]https://www.science.org/content/article/us-dairy-farm-worker-infected-as-bird-flu-spreads-to-cows-in-five-states[/url] or https://www.science.org/content/article/us-dairy-farm-worker-infected-as-bird-flu-spreads-to-cows-in-five-states ; The case is the latest surprise in the global march of the flu strain, a subtype of H5N1 known as clade 2.3.4.4b that has devastated wild birds and poultry around the world for more than two years. The U.S. Department of Agriculture (USDA) says it has confirmed that the virus has infected cattle at farms in Texas, Kansas, New Mexico, and Michigan, while Idaho has a “presumptive” outbreak at one dairy farm. Wild birds, which have been found dead on some farms, most likely contaminated cow feed or water. Some evidence suggests the virus was transmitted between cows, but that remains unproven. And for now, USDA says its “initial testing has not found changes to the virus that would make it more transmissible to humans.” Still, the widespread occurrence of H5N1 in mammals has renewed worries that it may evolve to become more transmissible between people. And scientists are urgently trying to answer a host of questions, including how far the virus has spread among U.S. cows and how to prevent more herds and people from becoming infected. Although cows routinely contract influenza viruses, this is the first time that a “highly pathogenic” bird flu strain has been found in them. USDA says about 10% of affected herds have become ill. Sick cows have a mild illness, and produce less milk, which is thicker than usual, resembling colostrum, the first milk produced after a calf is born. - Antibody tests of herds should soon reveal how widespread the infection is and how long it has been infecting cattle. Lab experiments may clarify how a virus that typically causes respiratory disease wound up in cow udders, making it detectable in their milk, and whether other organs are infected. No evidence exists that the virus has infected beef cattle, but researchers say that could simply be because of a lack of surveillance, or because these animals show subtler symptoms than changes in milk production and its appearance. - Although avian influenza viruses, first detected in humans in 1997, have caused outbreaks that killed hundreds of people, they have difficulty infecting human cells due to differences in the sugars that adorn human and bird cellular receptors for the virus. But humans have the bird version in our eyes, which explains why we can develop conjunctivitis. “I think the conjunctivitis in itself is not so serious, but it points to the fact that those people have been exposed and that they might develop respiratory disease,” says Thijs Kuiken, a comparative pathologist at Erasmus Medical Center who specializes in avian influenza. “I am really concerned about the people who are looking after affected cattle because I've heard of really high levels of virus in the milk and people are milking these animals twice a day.” The appearance of H5N1, clade 2.3.4.4b in cows was unexpected, even after its detection in dozens of mammalian species, including cats, dogs, foxes, tigers, leopards, coyotes, bears, seals, dolphins—and last month, goats at a Minnesota farm that also had an infected poultry flock. Cattle are often infected with type D, which one study shows can readily infect farm workers and cause disease, but H5N1 is a type A virus. “It’s definitely taken me by surprise, but perhaps it shouldn’t have,” says virologist Richard Webby of St. Jude Children’s Research Hospital. Idaho officials contend transmission of the virus between cattle occurred on a dairy farm there. That herd became sick after coming into contact with cows trucked in from an area in Texas where the virus was circulating. That “does lead state officials to believe cow-to-cow is how the virus was transmitted in this case,” a spokesperson for the Idaho State Department of Agriculture told Science. In Michigan, too, the virus surfaced after the importation of cows from Texas. - There are no H5N1 vaccines for cattle. Poultry vaccines do exist and are used heavily in China, with some marked successes. A crash program to develop a cattle equivalent might make sense, says Carol Cardona, an avian influenza specialist and poultry veterinarian at the University of Minnesota. If vaccinations can reduce viral spread, they might offer some secondary protection to dairy workers. “The person-to-cow ratio is so much higher than the person-to-chicken ratio,” notes Cardona, putting many more workers at risk. The cattle infections are “a game changer,” she adds. “I think it's all hands on deck.” David Swayne, who formerly ran the USDA’s avian influenza research lab, says it would be possible to quickly make a new cattle vaccine by modifying one now used in swine. And unlike with the bird vaccines, which are banned in the U.S. due in part to international trade concerns, swine vaccination is already “widely accepted,” Swayne says. The U.S. government stockpiles an H5N1 vaccine for humans, and CDC said in a statement today that vaccines developed for related viruses “are available for vaccine manufacturing” if preliminary studies show they protect against 2.3.4.3b. “As a protective measure you can imagine vaccinating dairy workers,” Kuiken says. The human infection in Texas has echoes of a massive outbreak of another highly pathogenic avian influenza virus, H7N7, in poultry flocks in the Netherlands in 2003 that Kuiken studied. Hundreds of people developed conjunctivitis, mainly during culling of infected flocks, and there was some evidence of human-to-human transmission. One veterinarian died. Kuiken advises the U.S. to restrict the movement of cattle to limit the spread of the virus. “I would take the precautionary principle and say, ‘OK, until we know what's going on, let's put a standstill on this,’” he says. But that is a controversial idea because the dairy industry relies on trucking cows south over the winters and then returning them north. And Armstrong doubts halting cattle transports would have much impact if migratory birds prove to be the main route of transmission. Many bird species are currently moving north and may be taking the virus with them. “It would be very surprising if it wasn't already everywhere,” Armstrong says, noting how difficult it is for farms to keep out birds. “We have to protect people, but we also have to … make sure we’re not crippling the industry,” he says. As to H5N1’s future, Cardona says we should continue to expect the unexpected. “The virus is making up new dances,” she says. “It’s broken the rules on everything.” DJ, Texas cows did spread H5N1 -very likely- further into other US states (so not the wild birds but transport of cows-infecting other cows...???) AVOIDING ANOTHER PANDEMIC SHOULD BE #1 !!!!!! Not -again- "saving economy".... |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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DJ, Did farm-cats start spreading H5N1 to cows ??? Cats eat dead birds-they may catch H5N1 that way...cat urine/poop may end up in a farm-reach cows that way ? Another suggestion infected wild bird-droppings in water infecting cows ? DJ-As far as I did read/follow the news; -Cow-to-cow spread idea based on Texas cows imported and start of H5N1 infections in other US states in cows/cattle... -Texas seems to be the H5N1-cow-hotspot...but there may be much less testing in other places.... -H5N1 spread in mammals -after contact with infected birds- has been going on for over 2 years... -So H5N1 an "increasing risk" for humans is not new.... [url]https://twitter.com/RajlabN/status/1775312873868132464/photo/1[/url] or https://twitter.com/RajlabN/status/1775312873868132464/photo/1 DJ, is a E627K mutation increasing risks for spread of H5N1 in mammals (including humans)???? link [url]https://twitter.com/WilliamJRipple/status/1775226048910962835/photo/1[/url] or https://twitter.com/WilliamJRipple/status/1775226048910962835/photo/1 Pandemic risks are related to a background-NEVER !!!!- isolated events.... End of part 1 |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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part 2; [url]https://afludiary.blogspot.com/2024/04/usda-confirms-infection-in-idaho-dairy.html[/url] or https://afludiary.blogspot.com/2024/04/usda-confirms-infection-in-idaho-dairy.html ; Although we've known since last week that preliminary tests had indicated HPAI in an Idaho Dairy herd, this afternoon the USDA has confirmed those test results, making Idaho the 5th state with confirmed HPAI in cattle. DJ, Very likely more testing will result in detecting more cases...So if one wants to deny a problem stop testing...it will make most problems a lot worse...But it -for now"- may "save the economy".... [url]https://afludiary.blogspot.com/2024/04/cdc-summary-analyses-of-genetic.html[/url] or https://afludiary.blogspot.com/2024/04/cdc-summary-analyses-of-genetic.html ; The CDC this evening has released their analysis of the HPAI H5N1 virus sampled from the human case in Texas, and reports that it is largely similar to HPAI viruses collected from dairy cattle in Texas.
DJ, so the virus in the Texas farm worker catching H5N1 -most likely- from the cows had the E627K mutation the cows did NOT show... Avian influenza in birds is predominantly a gastrointestinal malady, and is spread mostly via infected droppings. Birds run `hotter’ than mammals, which means avian flu viruses must adapt to lower temperatures found in the respiratory tract if they are to succeed in human or mammalian hosts. Additional adaptations are needed to make an avian virus a genuine pandemic threat (some we know about, while others we may not), but PB2-E627K is an important one often look for. DJ, In SouthEast Asia Cambodia and Vietnam had several human H5N1 infections...was it the same one as in this US, the two UK cases from april 1 ? Despite previous identification of PB2 E627K in human cases of HPAI A(H5N1) virus, there is no evidence of onward transmission among humans after infection with viruses containing this mutation. It is important to note that this substitution has not been seen in available PB2 genes from viruses circulating in wild birds and poultry or in the recently described cattle viruses detected in Texas, suggesting the mutation may have been acquired in the patient during the development of conjunctivitis. Viruses can undergo changes in a host as they replicate after infection, and it is not uncommon or surprising for HPAI A(H5N1) viruses to undergo this and other polymerase gene changes in infected patients (9). Additional data from A(H5N1) virus-infected animals from the premises where the person was likely exposed is needed to support this hypothesis. DJ so the H5N1 virus changed in the human host to better "spread" in the host... Collectively, epidemiologic, and viral genomic analyses indicate that this case represents a single zoonotic event and while the HA lacked changes likely to enhance transmission to mammals, it did acquire substitutions in PB2 likely to enhance replication in mammals, which illustrates that we have to remain vigilant and continue to characterize zoonotic viruses. So...pandemic risk (based on CDC-US data) remains low...More info on other H5N1 mammal infections may -however- need to review that idea... end of part 2, |
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Dutch Josh
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part 3, [url]https://flutrackers.com/forum/forum/national-international-government-ngo-preparation-response/who-oms/988128-who-avian-influenza-a-h5n1-viet-nam-2-april-2024[/url] or https://flutrackers.com/forum/forum/national-international-government-ngo-preparation-response/who-oms/988128-who-avian-influenza-a-h5n1-viet-nam-2-april-2024 ; 2 April 2024 Situation at a Glance The World Health Organization (WHO) was notified about a case of human infection with an influenza A(H5N1) virus on 25 March 2024 by the national authorities of Viet Nam. The patient, who had no underlying medical conditions, developed symptoms on 11 March and died on 23 March. Exposure to birds was ascertained to have taken place in the third week of February. Samples collected from close contacts tested negative for influenza A(H5N1) virus. This is the first human infection with an avian influenza A (H5N1) virus reported in Viet Nam since 2022. According to the International Health Regulations (IHR) 2005, a human infection caused by a novel influenza A virus subtype is an event that has the potential for high public health impact and must be notified to the WHO. Based on available information, WHO assesses the risk to the general population posed by this virus as low. Description of the Situation On 25 March 2024, Viet Nam National Focal Point (NFP) for International Health Regulations (IHR) notified the World Health Organization (WHO) of one case of human infection with an influenza A(H5N1) virus in a 21-year-old male with no underlying conditions from Khanh Hoa Province, Viet Nam. The case developed a fever and cough on 11 March 2024 and was admitted on 15 March to a local hospital due to persistent symptoms, including abdominal pain and diarrhoea. On 17 March, his condition worsened, and he was transferred to the Intensive Care Unit (ICU) of a provincial hospital. On 20 March, the patient was transferred to another provincial hospital with a diagnosis of severe pneumonia, severe sepsis, and acute respiratory distress syndrome. The case died on 23 March. On 19 March, samples were taken for real-time polymerase chain reaction (RT-PCR) testing by the Pasteur Institut in Nha Trang, which resulted in a positive result for the influenza (H5) virus. On 22 March, genomic sequencing conducted by the Pasteur Institut of Nha Trang revealed the presence of the avian influenza A (H5N1) virus. Initial results from the case investigation revealed that during the second and third weeks of February 2024, the case went bird hunting. Between that time and the onset of illness, no contact with dead or sick poultry nor contact with anyone exhibiting similar symptoms was reported. Among close contacts traced, no further cases of influenza A(H5N1) were detected. DJ, there may be more info on the clade/mutations... DJ...the cows only had limited symptoms...but H5N1 -maybe higher viral load/smaller animal-host- killed cats (???) [url]https://www.wormsandgermsblog.com/2024/04/articles/animals/cats/avian-flu-in-a-cat-on-a-dairy-farm-completely-unsurprising/[/url] or https://www.wormsandgermsblog.com/2024/04/articles/animals/cats/avian-flu-in-a-cat-on-a-dairy-farm-completely-unsurprising/ ; As part of the farm investigation, some (number not reported) sick (type of illness not reported) cats were tested, and three were positive. There’s no way to know for sure, but I’d guess that the cats were infected by the same source as the cows (i.e. from infected wild birds), not from the sick cows themselves. DJ...or did the cats catch H5N1 before the cows did ? Did they show symptoms before the cows had any symptoms ? It’s totally unsurprising, since there are various reports of cats from several countries around the world being infected with this virus, which continues to circulate widely in the wild bird population. Cats hunt birds, and birds that are sick with avian flu are a lot easier to catch. Eating a sick bird is a clear what to get infected, so it’s not surprising at all to find infected cats in areas where there’s lots of flu activity. I’d guess there have been hundreds of infections of cats worldwide, but most of them have gone unrecognized. DJ, very likely a much higher number of (wild) animals eating H5N1-infected birds may have been infected with H5N1. Very likely most of them may have had no or only mild symptoms. Dead mammals in areas with a high level of H5N1 in birds have been reported in many places...hardly any of them may have been tested... Wild pigs may be of even higher risks for H5N1 infection than cats, rats or mice... This isn’t a game changer, but it’s yet another reminder to pay attention. Fortunately, cats (like cows) don’t have their own influenza A virus, and they tend not to be very susceptible to human flu strains. So, there’s less risk of them being infected with the H5N1 virus and another flu virus at the same time, and acting as a mixing vessel for creation of a new, more problematic recombinant flu strain. However, every spillover into any mammal poses some extra risk, and cats are potential bridges between wildlife and people, since people often have close contact with cats. That’s why we’re on the lookout for these spillover infections, and ideally want to limit exposure of cats to infected wild birds. If you have cats that go outside and you can’t prevent that (not all cats can be indoor only), be on the lookout for flu. If an outdoor cat gets sick, especially with respiratory or neurological disease, and it’s had potential contact with flu-infected birds, it’s important to talk to your veterinarian (and ideally get the cat tested so we can gather more information on the virus’ behaviour, and also try to contain the infection). DJ...a very MAIN DRIVER is A-SYMPTOMATIC SPREAD !!!!!!!!!! Very likely most pandemics do become pandemics because not every host shows (much) symptoms !!!! In the US only cows with symptoms get tested...country/state fairs continue...Do we want a H5N1 pandemic ? A lot of animal-science is agri-culture science...NOT looking at PUBLIC health risks but on farm-economy...We have to change that perspective... |
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roni3470
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This mutation is the first of many as far as I am concerned. The speed at which it went from cow to cat to human is a little crazy. Now a 2nd person has it. I just dont think this is good. my son just got sick from his roommate, they both had pink eye and flu. He is in Arizona and hasn't had pink eye in like 10 years. This all has be so edgy! I hope and pray with all my heart that it stays mild and is no worse than a normal flu! |
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NOW is the Season to Know
that Everything you Do is Sacred |
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KiwiMum
Chief Moderator Joined: May 29 2013 Status: Offline Points: 29680 |
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Have a look at this YouTube video from the 12 minute mark. It's the Canadian Prepper and his view on the H5N1 situation and where he thinks it will lead us. It's very interesting. |
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Those who got it wrong, for whatever reason, may feel defensive and retrench into a position that doesn’t accord with the facts.
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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KiwiMum, interesting-good-video..."under reaction to over reaction"...CFR may be even less than 5% -at the start...Governments will use a H5N1 pandemic -they failed to stop- to increase further "population control"...Also further going after "spreading false info".... If people this time of year get eye problems, runny nose etc. it may be "just" hayfever.... However....H5N1 by now must be widespread in (wild) mammals...testing capacity may be very limited. So they now only test symptomatic cows, cats etc because of limits to testing capacity... Key mutations among the #AvianInfluenza sequences isolated from #Cats uploaded to #EpiFlu from #Poland | Analysis using #FluServer tool. Interesting #PB2 mutations: #E627K and #K526R https://cidrap.umn.edu/avian-influenza-bird-flu/polish-officials-probe-h5n1-avian-flu-link-cat-deaths - DJ, the july 1 -2023 tweet makes clear what role the K562R mutation plays in combination with E627K...increasing -in this case- H5N1 virus spreading in the (mammal) host...Humans are mammals... Somehow there may still be the idea "humans" are not linked to other animals...But "one health" what happens in humans may spread to other mammals (like CoViD) or the other way round; H5N1 jumping from birds to mammals and it may end up in humans... There are a lot of links I could include-but to keep this story to "the point" I will keep it limited...only if they provide new info...Ohio the 6th US state with H5N1 in cows is not "surprising"...Texas the "motor" behind H5N1 spreading in cows, cats also not surprising... We may see H5N1 in (farm) dogs...but it may stay limited there...for now. DJ-My view; H5N1 is moving us towards a flu-pandemic but it may NOT be a H5N1-flu... Like H1N1 in 1917/18 "Spanish Flu" it is how we deal with it that may matter most..."under reaction" a very major problem ! If a flu infects half of all humans -it would be in 4 billion people...If it killed 1% of them it would kill 40 million... Lots of other diseases around-very likely new diseases may increase as well...It may be the combination that is "very bad news"...At the end it may not matter what disease killed your family member, friend, partner...he/she is gone...very likely by a disease that should have been controlled... |
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Dutch Josh
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WAIT HOLD UP—Pasteurization of milk actually may **not** neutralize all viruses sufficiently to stop infectivity—“many viruses cannot”. It seems that fat globules in whole milk and 2% fat milk can protect viruses from high temperature pasteurization (dairy research shows for foot and mouth disease virus)—and show residual infectivity of the virus after pasteurization. My trusted colleague points out that the USDA & CDC has presented **zero evidence** avian flu cannot survive pasteurization in whole/2% fat milk. He warns that until such evidence is shown, we need to be careful of USDA/CDC’s claims that virus in milk can “reliably” be neutralized via current pasteurization temperatures. - 2) Contrast that above study with this USDA statement that “pasteurization would kill the virus” — but without any caveats or proven evidence. folks need to keep in mind that the U.S. Dept of Agriculture is actually the **COMMERCE AGENCY FOR AGRICULTURE**—it’s mission is to protect and help agriculture industry. Public health is a side priority. - 3) If we look at the study above, it seems that the pasteurization neutralized the virus in majority of the samples. But in 7 of the experiments… injection of the pasteurized milk sample into a naive uninfected steer ==> showed the cattle getting still infected from the pasteurized milk injection https://journalofdairyscience.org/article/S0022-0302(07)71769-1/fulltext - 4) In the U.S., pasteurization standard is 161 degrees F (or 71.7 Celsius) for a holding time of at least 15 seconds. Yet if we look at the temperatures and holding times in the study, we see the 7 samples that showed infectivity of pasteurized milk all above 72 C and 18 seconds… even pasteurized milk infectivity at 82.5 C and 36 seconds! - 5) There is another type of pasteurization called ULTRA-PASTEURIZATION, which requires heating to 280 degrees F (137.8 C) for 2 seconds. This is likely safest. Try to find **ultra-pasteurized milk if possible**. - 6) Caveats: the study in infectivity of pasteurized milk is for foot and mouth disease virus, not avian flu. The infectivity is for injection of the milk into a naive uninfected steer, not ingestion of the milk orally. We need true data on avian flu virus titer in pasteurized milk from USDA and CDC to know for sure. - - 8) Side datapoint on cats— cats have died of avian flu already. It seems that cats maybe getting the flu virus from somewhere like in their water (or eating dead birds) are "ingesting" and thus maybe how they got infected. A lot of variables that are very easily tested experimentally. Best thing to do is experiment and discuss, vs just blanket assume safety. -DJ- Maybe small cats get more ill from a same viralload compared to big cows...Would a small child see more severe disease with a same viral load that gets a 100 kilo male down ? Of course ! 9) speaking of ingesting the virus, public health officials have already warned about avian flu from raw and undercooked eggs. So ingesting the virus is a thing. And by *cooked* eggs — we mean no “runny” eggs with undercooked egg yolk! Fully cooked eggs only folks. DJ, may also include products with un(der)cooked eggs... 10) Eye infection of avian flu is a thing as well. Scientists have directly warned about conjunctivitis in humans from avian flu because our eyes have the same type of sugar-complexes as birds that allows the avian flu to infect. Eye-protection ! May also help a bit against hayfever...summer on its way... 12"There is massive (unprecedented) exposure of wild carnivores (feasting on sick/dead birds) and potentially also other mammals (through contaminated water and surface areas, including grasslands),” Ron Fouchier, an influenza virologist at Erasmus Medical Center in Rotterdam. “The infected mammals get infected upon feeding/drinking, which is an alternative route of infection of mammals.” we seriously need USDA & CDC to do a study of virus titer level needed for ingestion infection https://statnews.com/2024/04/03/h5n1-bird-flu-in-cows-risk-to-humans/ DJ-old news-number of infected mammals/spread in mammals big question.. |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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DJ, H5N1 will be used as distraction for the latest NATO criminal disasters in UKraine and USrael...Some western crazy leaders may accuse Putin of infecting US cows with H5N1, blame China for another "lab-leak"...not based on any evidence...but it may distract from total western politics failure... H5N1 is affecting egg-production. Some mega-farms did see H5N1 in their chickens... A welcome outcome of -yet another- pandemic may be rethinking meat consumption...do we need milk, eggs that much ? Farm animals ARE a pandemic risk! Alternatives for meat (etc) are getting better... [url]https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza/hpai-detections/livestock[/url] or https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza/hpai-detections/livestock on H5N1 spread in US cows/cattle... DJ, transporting animals for days, treating them as "things" is just as bad as "wars for profits"... We need better leaders !...it should not be that hard to find more intelligent ones...But a "powerblock" is using the present crazy leaders to fill up their pockets ! CDC’s updated website info on bird flu— “Human infections with bird flu viruses have most often occurred after close or lengthy unprotected contact (i.e., not wearing gloves or respiratory protection or eye protection) with infected birds or places that sick birds or their saliva, mucous and feces have touched. Very rarely, human infections with bird flu viruses have happened through an intermediary animal, including a cat and a cow. Human infections with bird flu viruses can happen when virus gets into a person’s eyes, nose or mouth, or is inhaled. This can happen when ***virus is in the air** (in droplets or possibly dust) and a person breathes it in, or possibly when a person touches something that has virus on it and then touches their *mouth , eyes or nose . https://cdc.gov/flu/avianflu/inhumans.htm DJ, mutations in H5N1 could bring higher viral loads spread via aerosols of dried up "droppings"... CoViD-still widespread-may decrease immunity protection against H5N1...so give H5N1 more chance to spread in hosts-post Covid ! [url]https://flutrackers.com/forum/forum/the-pandemic-discussion-forum/987828-discussion-thread-h5n1-avian-flu-in-us-dairy-cows-march-24-a-human-case-in-texas-april-1?view=stream[/url] or https://flutrackers.com/forum/forum/the-pandemic-discussion-forum/987828-discussion-thread-h5n1-avian-flu-in-us-dairy-cows-march-24-a-human-case-in-texas-april-1?view=stream and [url]https://flutrackers.com/forum/forum/united-states/h5n1-tracking-af/987593-us-dairy-cows-test-positive-for-h5n1-avian-flu-in-texas-kansas-idaho-michigan-new-mexico-ohio-march-24-one-texas-human-case-april-1?view=stream[/url] or https://flutrackers.com/forum/forum/united-states/h5n1-tracking-af/987593-us-dairy-cows-test-positive-for-h5n1-avian-flu-in-texas-kansas-idaho-michigan-new-mexico-ohio-march-24-one-texas-human-case-april-1?view=stream may provide latest (good) info... DJ-Outside the US cows, other farm "mammals". may see H5N1 but there may be -so far- no testing... [url]https://www.dutchnews.nl/2024/04/air-pollution-cost-hundreds-of-lives-during-coronavirus-pandemic/[/url] or https://www.dutchnews.nl/2024/04/air-pollution-cost-hundreds-of-lives-during-coronavirus-pandemic/ [url]https://nltimes.nl/2024/04/01/lung-alliance-warns-shortage-asthma-medication-especially-children-affected[/url] or https://nltimes.nl/2024/04/01/lung-alliance-warns-shortage-asthma-medication-especially-children-affected [url]https://nltimes.nl/2024/04/04/whooping-cough-measles-cases-rising-politicians-demand-action-vaccine-rates[/url] or https://nltimes.nl/2024/04/04/whooping-cough-measles-cases-rising-politicians-demand-action-vaccine-rates ...for economic reasons...lots of countries may postpone testing in farm animals...(Here in NL "political blabla/worries"). Big Pharma may see another oppertunity for mega-profits...we keep repeating mistakes till those mistakes end us... |
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Dutch Josh
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[url]https://afludiary.blogspot.com/2024/04/fao-statement-on-reassortment-between.html[/url] or https://afludiary.blogspot.com/2024/04/fao-statement-on-reassortment-between.html ; While the rest of the world has been wrestling with an upstart clade 2.3.4.4b H5N1 virus, in Cambodia (and more recently Vietnam) they have been dealing with the return of an older clade of the virus - 2.3.2.1c - which has resulted in 11 human infections over the past 14 months. DJ, different subtypes of same virus !
Today, without explicitly mentioning that case, the FAO in Vietnam released the following statement regarding the recent appearance of a reassorted H5N1 virus that has the surface proteins from the older 2.3.2.1c clade, but the internal genes from the newer 2.3.4.4b clade of the virus. -and that may be bad news....
While it isn't clear how much of a threat this new reassorted virus currently poses, each evolutionary change is a stepping stone to the next. A process that over time, could eventually lead to a more dangerous virus. I've posted the full statement from the FAO below. Hopefully we'll get some more details on its pathogencity and/or transmissibility sooner rather than later. - There has been dominance of influenza A(H5N1) clade 2.3.4.4b virus circulation around the world since 2021. Avian influenza A - H5N2, H5N4, H5N5, H5N6 and H5N8 subtypes have all been sporadically detected in poultry or wild birds. From December 2023 to February 2024, at least 646 HPAI outbreaks have been reported in five geographic regions caused mainly by A(H5N1) (610). In Asia, several clades continue to circulate, including A(H5N1) 2.3.4.4b, 2.3.2.1c and others, which can lead to reassortment and the appearance of viruses with new characteristics. A novel reassortant influenza A(H5N1) virus has been detected across the Greater Mekong Subregion (GMS), causing infections in both humans and poultry since mid- 2022. This virus has recently caused human outbreaks in Cambodia early this year. This virus contains the surface proteins from clade 2.3.2.1c that has circulated locally, but internal genes from a more recent clade 2.3.4.4b virus. The introduction and widespread circulation of this reassortant influenza A(H5N1) virus into the GMS poses a significant risk to both animal and human health, given the historical impact of HPAI outbreaks in the region. Further, this reassortment event indicates not only the adaptive capacity of the virus but also the ever-present risk of the emergence of new, potentially more virulent strains. Phylogenetic examination of HPAI A(H5N1) viruses sampled from live poultry markets and outbreaks between January 2022 and December 2023 revealed continued circulation of both clades 2.3.2.1c and 2.3.4.4b in Vietnam. Clade 2.3.2.1c predominantly circulated in southern Vietnam, while clade 2.3.4.4b was found nationwide. A small number of HPAI A(H5N1) viruses detected in live poultry markets in the southern provinces collected in 2023 exhibited reassortment between clade 2.3.2.1c and 2.3.4.4b genes, however no PB2-E627K substitution was detected. Since December 2023, five human cases of infection with A(H5N1) influenza viruses were notified to WHO from Cambodia. The A(H5N1) viruses from the first four cases belong to the H5 haemagglutinin (HA) clade 2.3.2.1c. Viruses belonging to this clade have been detected in poultry since 2014 in Cambodia in longitudinal surveillance done in the animal health sector. DJ, time will tell if the new variant will spread more in humans... |
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Dutch Josh
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Another article; [url]https://www.statnews.com/2024/04/05/bird-flu-ron-fouchier-h5n1-risk-to-people/[/url] or https://www.statnews.com/2024/04/05/bird-flu-ron-fouchier-h5n1-risk-to-people/ ; To put these developments in perspective, STAT turned to Dutch virologist Ron Fouchier, a leading expert on H5N1, for his assessment of these latest twists in the H5 saga. Fouchier, who studies avian influenza at the Erasmus Medical Center in Rotterdam, was at the center of a controversy about H5N1 in 2012, when a U.S. scientific advisory group moved to restrict publication of research he and a team at the University of Wisconsin-Madison had done — separately — to see what mutations would be needed for the virus to be able to spread efficiently among people, so-called gain of function research. Fouchier takes little solace from the fact that current versions of H5N1 seem to infect people less frequently, and to cause mostly mild illness when they do. The global range of H5 viruses — the sheer volume of the virus in nature — and the numbers of mammals H5 has shown itself capable of sickening is unprecedented, he said, making anticipating its future path harder than ever to gauge. - link [url]https://www.science.org/content/article/bird-flu-may-be-spreading-cows-milking-and-herd-transport[/url] or https://www.science.org/content/article/bird-flu-may-be-spreading-cows-milking-and-herd-transport DJ |
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Dutch Josh
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Dutch Josh
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DJ, There is the VERY WRONG IDEA high spread/R0 may mean low CFR....Both CoViD and H5N1 are widespread in many species !!!! So both diseases will NOT run out of hosts for spread...humans are just one of many species both diseases may spread in... [url]https://www.wormsandgermsblog.com/2024/04/articles/animals/other-animals/h5n1-avian-flu-in-cattle-what-farmers-vets-governments-and-consumers-can-do-now/[/url] or https://www.wormsandgermsblog.com/2024/04/articles/animals/other-animals/h5n1-avian-flu-in-cattle-what-farmers-vets-governments-and-consumers-can-do-now/ H5N1 avian flu in cattle: what farmers, vets, governments and consumers can do nowBy Scott Weese on POSTED IN OTHER ANIMALS DJ, we need to take H5N1 VERY SERIOUS !!! Masks/eyeprotection DO WORK !!! |
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Dutch Josh
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link; [url]https://www.cnbctv18.com/healthcare/experts-say-h5n1-bird-flu-pandemic-might-be-100-times-worse-than-covid-19-how-to-stay-safe-19392658.htm[/url] or https://www.cnbctv18.com/healthcare/experts-say-h5n1-bird-flu-pandemic-might-be-100-times-worse-than-covid-19-how-to-stay-safe-19392658.htm ; "This virus (has been) on the top of the pandemic list for many, many years and probably decades... And now we are getting dangerously close to this virus potentially causing a pandemic," DailyMail quoted Dr Suresh Kuchipudi, a bird flu researcher in Pittsburgh, as saying. DJ, CoViD and H5N1 do NOT exclude eachother...we could see a "mega-mix" of diseases... link; [url]https://www.cidrap.umn.edu/avian-influenza-bird-flu/officials-warn-h5n1-avian-flu-reassortant-circulating-parts-asia[/url] or https://www.cidrap.umn.edu/avian-influenza-bird-flu/officials-warn-h5n1-avian-flu-reassortant-circulating-parts-asia ; Animal health officials in Vietnam and with the United Nations Food and Agriculture Organization (FAO) today urged countries to be on alert for a new highly pathogenic avian influenza (HPAI) H5N1 reassortant virus in chickens and mescovy ducks, which was found during active surveillance. In a statement, the FAO said the virus is a reassortant between the older H5N1 clade (2.3.2.1c) that is still circulating in parts of Asia and a newer H5N1 clade (2.3.4.4b) that began circulating globally in 2021. A reminder about the virus' ability to adaptThe reassortant virus contains surface proteins of the older clade virus and internal genes from the more recent virus clade. The reassortant has been circulating across the Greater Mekong subregion, causing infections in birds and people since the middle of 2022. The FAO said the virus has been linked to human infections, though it didn't specify which ones. DJ, related; #H5N1 Clade 2.3.2.1c - #Vietnam New sequence from Khanh Hoa has intriguing #avianflu reassortment and PB2-E627K mammalian adaptation signature. PB2-E627K was absent in previously submitted avian sequences. Case description: https://fao.org/vietnam/news/detail-events/en/c/1680337/ There may be more "new H5N1 variants" in mammals...we simply can impossible test all possible hosts...Not even all sick ones... link; [url]https://www.cbc.ca/news/health/avian-flu-h5n1-cow-outbreaks-1.7162626[/url] or https://www.cbc.ca/news/health/avian-flu-h5n1-cow-outbreaks-1.7162626 ; And a rising number of mammals are also getting infected, from mink to seals to domestic dogs and cats. This March, prior to the discovery of cases among cattle, Minnesota reported an H5N1 infection in a young goat, marking the first known U.S. case of bird flu in a ruminant. (Cows are also ruminants, a group of herbivores known for their four-chambered stomachs.) - "Dairy cows have not been affected before in the United States, or anywhere else in the world to my knowledge, and we've never before seen such clear evidence of mammal-to-mammal transmission," said Caitlin Rivers, an epidemiologist at the Johns Hopkins Center for Health Security in Baltimore. That possibility of spread between cows "does take us, maybe, a half-step closer to a scenario where the virus would be better adapted for humans," she told CBC News. What's even more concerning, several researchers agreed, is the growing potential for bird flu to spread to another species of livestock: Pigs. Pigs considered viral mixing vesselsWhile cattle aren't known for being an ideal host for many flu viruses, pigs are potent viral mixing vessels. That's because swine have both human-adapted receptors and avian-adapted receptors in their respiratory tracts, Moncla said, meaning they can be infected with either type of pathogen. If a pig catches both a human influenza A virus and an avian influenza A virus at the same time, it can spark a process known as viral reassortment — a genetic exchange in which flu viruses swap gene segments. Those swaps can introduce dramatic changes, producing a new virus with certain properties of a non-human strain coupled with the capacity to infect and spread between people. That sort of shift hasn't been documented yet with H5N1. But it did happen with a new form of H1N1 — a virus resulting from a mashup of genes between various pig, bird, and human flu viruses — which began infecting people for the first time in 2009, sparking a pandemic. Death rates from H1N1 were higher than typical flu seasons, but it eventually began circulating alongside other seasonal flu viruses and is now included in annual flu shots. Moncla said her "worst fear" is something similar happening with highly pathogenic avian flu, given its health impacts. - 'It might not ever leave'There are no signals that H5N1 has spread to pigs, at least for now. It also hasn't appeared yet in Canadian livestock, including dairy cattle, according to the Canadian Food Inspection Agency. But scientists on both sides of the border worry it's just a matter of time if swift action isn't taken to contain outbreaks and heighten surveillance. - Dairy producers, scared for their livelihoods, can be wary of reporting sick cattle, given poultry producers are often forced to cull entire flocks experiencing H5N1 outbreaks, Armstrong said. More human cases could also be happening under the radar among farm workers who've moved to the U.S. from abroad, don't speak English as their first language, and may be hesitant to seek medical help, he added. "So I think there's probably underreporting on both sides," Armstrong said. "If [H5N1] gets into a population where there's constantly animals going in and out … it might not ever leave." DJ, Economic damage may result in NOT reporting...even human (mild) cases...Lots of countries WILL miss spread... |
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Dutch Josh
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DJ, H5N1 is now "main stream news"... -A cow-to-human infection in the US is "new" (maybe the infected man also did drink raw milk ? A higher viral load ? Milking cows may see aerosol spread-human eyes may have receptors for the "cow-virus") -After spread of H5N1 in South American sea lions we may see cow-to-cow, possibly even cat-to-cat spread ? -Two subtypes of H5N1 mixed in a Vietnam man-killing him... -We do NOT see any human-to-human spread of H5N1, also human cases-even if we miss some a/mild-symptomatic cases must be "extremely rare"! So...how close are we to a H5N1 pandemic ? The virus would need some more mutations before we may see H5N1 creating a pandemic itself. However H5N1 mixing with a high risk "human" type of (H1/H2/H3) flu may increase indirect risks of a flu-pandemic... [url]https://www.wormsandgermsblog.com/2024/04/articles/animals/cats/h5n1-avian-flu-in-catswhat-do-we-know-so-far/[/url] or https://www.wormsandgermsblog.com/2024/04/articles/animals/cats/h5n1-avian-flu-in-catswhat-do-we-know-so-far/ ; Although H5N1 infections in cats can be severe, social media claims of “100% mortality” are overblown As we’ve seen in many other mammals with spillover infections (but fortunately not humans so far), infected cats can have very severe disease, including fatal infections, typically with severe neurological signs. It can be very bad, but it’s presumably nowhere near 100% fatal.
We don’t know whether H5N1 infected cats can be infectious to others With only a small number cats tested, it’s hard to gauge the risk of transmission from cats to other animals (or people). Hopefully we’ll get more information about the cats on infected dairy farms. DJ, cat-to-cat spread may need lab testing... [url]https://afludiary.blogspot.com/2024/04/vietnam-moh-statements-on-ah9-case-in.html[/url] or https://afludiary.blogspot.com/2024/04/vietnam-moh-statements-on-ah9-case-in.html ;
As an LPAI (low path avian influenza) virus, H9N2 is not considered a `reportable' disease by WOAH (formerly the OIE), even though it is zoonotic. We've seen seroprevalence studies which suggest people with exposure to infected poultry often develop H9 antibodies, suggesting mild or asymptomatic infection
- Since then, we've seen roughly 130 confirmed LPAI H9N2 cases around the world, and a smattering of other LPAI human infections, including A(H6), A(H7), A(H9), and A(H10) viruses. - While we are understandably keeping a close watch on HPAI H5N1, LPAI viruses are quite capable of jumping to humans, and causing equally severe illness.
Even if most don't appear to be as deadly as H5N1, even a 2% CFR (Case Fatality Rate) pandemic would make COVID pale in comparison. And that is something the world remains poorly prepared to deal with. DJ, you do not want to see H5N1 mix with H9N2 either... |
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Dutch Josh
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link [url]https://journals.lww.com/academicmedicine/fulltext/2021/07000/a_call_for_one_health_in_medical_education__how.31.aspx?utm_source=twitter&utm_medium=acadmedjournal&utm_content=f9f6f3b2-fb50-495b-8c47-6dcc2a9312fa[/url] or https://journals.lww.com/academicmedicine/fulltext/2021/07000/a_call_for_one_health_in_medical_education__how.31.aspx?utm_source=twitter&utm_medium=acadmedjournal&utm_content=f9f6f3b2-fb50-495b-8c47-6dcc2a9312fa ; AbstractDuring the early stages of the COVID-19 pandemic in 2020, the first author, then a fourth-year student at Harvard Medical School, was enrolled in a One Health clinical experience at Zoo New England where he was introduced to a transdisciplinary approach to integrate human, animal, and ecosystem health. Seeing the vast impact of the pandemic and knowing its roots as a zoonotic disease, he realized this approach was critical to his medical education and for preparation against future novel infectious diseases. Zoonotic diseases have been emerging into human populations with increasing frequency, leading to public health emergencies such as Ebola, avian influenza, and SARS. The SARS-CoV-2 narrative, starting in bats and then mutating through an intermediate host into humans, is another striking example of the interconnectedness between human, animal, and ecosystem health that underlies these infections. Preventing future pandemics will require a transdisciplinary One Health approach, and physicians should be prepared to participate in these discussions while advocating for One Health initiatives for the benefit of their current and future patients. Integration of One Health education into medical school curricula will also prepare future physicians for other complex and urgently important health issues such as climate change, antimicrobial resistance, and the impact of biodiversity loss. DJ...sad to see this 2021 article -like many other calls for "one health"- simply is ignored to "save the economy"... DJ, number of US farms with H5N1 in cattle keeps increasing-in part because testing keeps increasing...I do NOT believe -for a moment- only US cows catch H5N1... H5N1: "Milk production fell and the cows were lethargic and weren’t eating much." “We hadn’t seen anything like it before, it was kind of like they had a cold.” Note: This does not sound like a virus that is only infecting cow's udders. link; [url]https://thehill.com/homenews/nexstar_media_wire/4579276-chickens-and-cattle-hit-with-massive-bird-flu-outbreak-will-food-prices-go-up/[/url] or https://thehill.com/homenews/nexstar_media_wire/4579276-chickens-and-cattle-hit-with-massive-bird-flu-outbreak-will-food-prices-go-up/ ; DJ-Yes...it will push up food prices...There are alternatives for meat and eggs... link; [url]https://www.sciencedirect.com/science/article/pii/S1477893924000358[/url] or https://www.sciencedirect.com/science/article/pii/S1477893924000358 ; This divergence from the typical avian host raises alarms, as avian influenza rarely infects cattle. The USDA's confirmation of HPAI A(H5N1) presence in multiple herds, particularly in states not historically associated with avian influenza outbreaks, underscores the gravity of the situation. The identified strain, belonging to the Eurasian lineage of H5N1 goose/Guangdong virus clade 2.3.4.4b, is suspected to have been introduced by wild migratory birds. Symptoms exhibited by infected cows, including decreased milk production, altered milk consistency, and diminished appetite, further accentuate the severity of the situation. Furthermore, the emergence of the virus in a human case in Texas, although with low risk of transmission, accentuates the need for heightened vigilance and response measures. DJ, as far as I know the US spread in cows and cats is the same "clade/subvariant" that did see spread in sealions in South America...Somehow "some countries" fail to look beyond their own borders... H5N1 is NOT ONLY a US story !!! There is no point in calling for "one health" if you are unable to "think" outside -in this case- the US ! [url]https://www.thailandmedical.news/news/breaking-new-measles-d8-variant-in-italy-that-evades-current-test-spreading-silently-in-italy-with-over-231-cases-in-the-first-three-months-of-2024[/url] or https://www.thailandmedical.news/news/breaking-new-measles-d8-variant-in-italy-that-evades-current-test-spreading-silently-in-italy-with-over-231-cases-in-the-first-three-months-of-2024 DJ-Did the CoViD-pandemic "open the doors" to lots of other diseases in mammals ? "We" ignored CoViD in non-human hosts..."one health" not much more than a good idea...We ignored H5N1 spread-around the globe-from birds into mammals...We knew it happened already a few years ago...Dead infected birds were eaten...so the virus could/would spread...and we let it happen... Picking up dead infected birds was "not cost effective" in the "short term"...somehow we are now "surprised" in the somewhat longer term ? |
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Dutch Josh
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- "...The results show that rapid testing can be used to detect avian influenza viruses in poultry." link; [url]https://research.wur.nl/en/publications/inventarisatie-van-sneltesten-voor-vogelgriep-kd-2022-096[/url] or https://research.wur.nl/en/publications/inventarisatie-van-sneltesten-voor-vogelgriep-kd-2022-096 (Dutch-google translate !) DJ, Rapid testing can help contain spread. [url]https://www.nature.com/articles/d41586-024-01036-1[/url] or https://www.nature.com/articles/d41586-024-01036-1 ; If the virus is spreading between cows, it will be important to work out precisely how, Webby says. Evidence so far suggest that virus levels are highest in the animals’ milk, according to a report in Science. That suggests that H5N1 might not be spreading between cows through the air, a transmission pathway that would be difficult to control and could allow for relatively quick spread, Webby says. If cows are becoming infected by touching contaminated surfaces, such as milking machines, the virus would be transmitted more slowly than if it is airborne. Gathering evidence to address these questions could help to answer why infections have only recently cropped up in cattle, and only in the United States, despite the virus’s global spread in the past few years. Marion Koopmans, a virologist at Erasmus University Medical Center in Rotterdam, the Netherlands, wonders whether there is something unique about how cattle are kept in the region, for example, or whether the virus has gained new abilities to persist in the environment. Addressing these questions will offer insights into how widespread bird flu infections could be in cattle globally, she says. It will be important for health officials outside the United States to start looking for evidence of overlooked outbreaks, Krammer says. DJ, lots of countries will have been looking for H5N1 in their cattle...I do NOT believe they would keep any detections a secret...So WHY so far only US cows show H5N1 ? [url]https://afludiary.blogspot.com/2024/04/emerg-microb-inf-long-term-co.html[/url] or https://afludiary.blogspot.com/2024/04/emerg-microb-inf-long-term-co.html ; Twice in my lifetime (1957 and 1968) avian flu viruses have reassorted with seasonal flu and launched a human pandemic.
Pigs are often cited as the `classic mixing vessel' - and were the source of the 2009 H1N1 pandemic - but increasingly we are seeing flu viruses spreading into new mammalian hosts; including mink, cats, dogs, and marine mammals. - Two months ago, in Virologica Sinica: The Evolution, Pathogenicity & Transmissibility of Quadruple Reassortant H1N2 Swine Influenza Virus in China, we looked at a worrisome report on a Quadruple Reassortant H1N2 virus (2 human, & 2 swine subtypes) circulating in pigs in China, which already replicates efficiently in human, canine, and swine cells and mice. Today, thanks to a reader who sent me the link, we have another report on the growing diversity of swine flu viruses circulating in pigs, this time in Guangxi, China. While the Swine-variant EA H1N1 `G4' virus - which we've been following since 2015 - continues to dominate, researchers reported the co-circulation of a number of swine viruses, including the discovery of a novel quadruple reassortant H1N2 virus with an M gene from H9N2.
While this H1N2 virus doesn't appear to have been `fit' enough to gain a permanent foothold, it illustrates how convoluted, and unpredictable, the evolution of swine viruses has become. DJ, again-lots of mixing willNOT be noticed ! Basic statistics learn more H5N1 spread means increase of risk-mix of H5N1 with other types of flu...pigs seen as high risk "mixing vessel"-but also humans (over 8 billion !) are "high risk" [url]https://www.statista.com/statistics/263964/number-of-pigs-in-selected-countries/#:~:text=Global%20overview,tons%20of%20pork%20each%20year.[/url] or https://www.statista.com/statistics/263964/number-of-pigs-in-selected-countries/#:~:text=Global%20overview,tons%20of%20pork%20each%20year. ; Global overviewThere were about 778.64 million pigs worldwide as of April 2022, meaning that China was home to more than half of the global pig population. Unsurprisingly, China is the leading pork producer worldwide, producing about 50 million metric tons of pork each year. DJ, Since humans move more free than most pigs (even the wild ones-very likely NOT in this number) human "mixing vessels" are a larger risk... [url]https://flutrackers.com/forum/forum/china-other-health-threats/china-government-ngo-preparation-and-response/988364-china-tianyang-district-holds-a-drill-for-high-pathogenic-avian-flu-in-animals-guangxi-province-march-27-2024[/url] or https://flutrackers.com/forum/forum/china-other-health-threats/china-government-ngo-preparation-and-response/988364-china-tianyang-district-holds-a-drill-for-high-pathogenic-avian-flu-in-animals-guangxi-province-march-27-2024 ; On the morning of March 22, the 2024 Tianyang District emergency response drill for a sudden highly pathogenic avian influenza epidemic was launched in the second office area of the Tianyang District Agriculture and Rural Affairs Bureau. The heads of relevant business units, second-level institutions and technical personnel under the District Agriculture and Rural Affairs Bureau and the Aquatic Animal Husbandry and Veterinary Bureau , as well as the directors of the aquatic animal husbandry and veterinary stations in each township and representatives of animal epidemic prevention cooperatives participated in the drill. DJ, Do western countries have such drills ? If not-why not ??? |
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Dutch Josh
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[url]https://www.wormsandgermsblog.com/2024/04/articles/animals/other-animals/dairy-cattle-and-h5n1-flu-update/[/url] or https://www.wormsandgermsblog.com/2024/04/articles/animals/other-animals/dairy-cattle-and-h5n1-flu-update/ ; Dairy cattle and H5N1 flu updateBy Scott Weese on POSTED IN OTHER ANIMALS DJ, more, better, fast testing may; -result in ( a few more) detections -so we could expect number of infected farms/states with H5N1 in cows to increase -find out IF there is any spread outside the US link; [url]https://www.science.org/content/article/bird-flu-discovered-u-s-dairy-cows-disturbing[/url] or https://www.science.org/content/article/bird-flu-discovered-u-s-dairy-cows-disturbing (march 26-no new info) DJ- For now "indications" H5N1 in cattle may be a US issue...H5N1 is high risk in lots of mammals (Sealions, cats, minks) but -so far- NOT detected in cows outside the US... ------ [url]https://flutrackers.com/forum/forum/vietnam/current-emergency-situations-ab/988308-vietnam-khanh-hoa-department-of-health-%E2%80%8B%E2%80%8B%E2%80%8B%E2%80%8B%E2%80%8B%E2%80%8B%E2%80%8Bissued-an-emergency-dispatch-to-a-series-of-students-in-nha-trang-suspected-of-food-poisoning?view=stream[/url] or https://flutrackers.com/forum/forum/vietnam/current-emergency-situations-ab/988308-vietnam-khanh-hoa-department-of-health-%E2%80%8B%E2%80%8B%E2%80%8B%E2%80%8B%E2%80%8B%E2%80%8B%E2%80%8Bissued-an-emergency-dispatch-to-a-series-of-students-in-nha-trang-suspected-of-food-poisoning?view=stream ; April 8, 2024 09:44 GMT+7 DJ...chicken with H5N1 ????? So "food poisening" might be linked to H5N1 ???? ...related ???? DJ, South East Asian H5N1 spread-possibly coinfections with other types of flu-in humans, pigs, may be more of a risk then the US-"cow-flu"... Very likely poultry workers worldwide also "run H5N1 risks"...masks/eye-protection should be "the norm"... |
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Dutch Josh
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link [url]https://www.telegraph.co.uk/global-health/science-and-disease/chicken-waste-fed-to-cattle-may-be-behind-bird-flu-outbreak/[/url] or https://www.telegraph.co.uk/global-health/science-and-disease/chicken-waste-fed-to-cattle-may-be-behind-bird-flu-outbreak/ ; Experts warn that lax regulations could also see the virus spread to US pig farms, with serious consequences for human health Fears are growing that the H5N1 outbreak among cattle in the United States could have been caused by contaminated animal feed. In contrast to Britain and Europe, American farmers are still allowed to feed cattle and other farm animals ground-up waste from other animals including birds. The US Food and Drug Administration (FDA) now has the safety of that policy under review, a spokesperson said on Tuesday. Dairy cows across six US states – and at least one farm worker – have become infected with the highly pathogenic virus, which has already killed millions of animals across the globe since 2021. The farm worker, who is thought to have been exposed via infected cattle in Texas, is only the second recorded human H5N1 case in the US – although 8,000 possible exposures are currently under investigation, according to Dr Joshua Mott, WHO senior advisor on influenza. The development is of concern because it allows the virus, which has killed millions of birds and wild mammals around the world, more opportunities to mutate. DJ...age of stupid !!!! [url]https://afludiary.blogspot.com/2024/04/virus-evol-hpai-ah5-clade-2344b-in.html[/url] or https://afludiary.blogspot.com/2024/04/virus-evol-hpai-ah5-clade-2344b-in.html ; Seven years ago, I opened a blog writing:
Of course, what seemed like a rapid spread and diversification of H5Nx viruses back then pales in comparison to what we've seen over the past 3 years.
As a segmented virus with 8 largely interchangeable parts, the flu virus is like a viral LEGO (TM) set which allows for the creation of unique variants called genotypes. The result being that we aren't facing a single HPAI H5N1 virus, but an array of (dozens) of similar H5 viruses, all on their own evolutionary path. DJ, maybe for the US government...We need to CONTAIN H5N1 !!!! NOT SPREAD IT !!!! @#$%&#$*&@!!!!!!!! [url]https://flutrackers.com/forum/forum/united-states/h5n1-tracking-af/987593-us-dairy-cows-test-positive-for-h5n1-avian-flu-in-texas-kansas-idaho-michigan-new-mexico-ohio-march-24-one-texas-human-case-april-1?view=stream[/url] or https://flutrackers.com/forum/forum/united-states/h5n1-tracking-af/987593-us-dairy-cows-test-positive-for-h5n1-avian-flu-in-texas-kansas-idaho-michigan-new-mexico-ohio-march-24-one-texas-human-case-april-1?view=stream .... DJ...I need a drink ! |
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Dutch Josh
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- DJ...if the US is SPREADING !!!! H5N1 via "poultry litter" getting cows, cats (etc???) infected maybe an international court can "correct" the US ??? link; [url]https://www.dtnpf.com/agriculture/web/ag/news/article/2024/04/08/researchers-continue-look-source[/url] or https://www.dtnpf.com/agriculture/web/ag/news/article/2024/04/08/researchers-continue-look-source ; REDFIELD, Iowa (DTN) -- As the influenza virus is found in more dairy herds in several states, veterinarians and researchers continue to find out more about the illness. So far, no cows have died, but the virus already has caused about 20% income loss in affected operations. "I hate to compare this to COVID, but as we find out new things every day, I feel like it's the same thing we heard during the pandemic," said Fred Gingrich, executive director of the American Association of Bovine Practitioners. "We are finding out new things daily about this virus and how it's affecting infected dairy cows. We didn't know anything about this until now." Gingrich said influenza in animals is treated the same as it is in people, with supportive care. There's no real treatment since it is a virus. Instead, cows are given extra fluids, offered proper nutrition, and given anti-inflammatory medicines if a secondary infection is found such as mastitis or pneumonia. - Affected dairy cows are reported as being off feed, which is likely the first indication of sickness. Their milk is thick, and thus, they are getting pulled from the milking herd and usually tested first for mastitis. Their manure appears tacky during this sickness. "Cows are pulled on day two to five and put in the hospital pen for surveillance and treatment. It seems to be affecting about 10% of the herd, and by day 14 to 21, the cows have recovered," he added. "A decrease in milk production is a big effect on these herds. We will see up to a 20-pound loss in production per cow, which, in the end, is a 20% loss in income for these producers." DJ..so sick cows with H5N1 are NOT isolated from other (ill) cows ???? DJ, Cows infecting humans is NOT new! DJ, many experts must be shocked.... The "good news" is poultry litter may explain why we do not see H5N1 in cows outside the US....The bad news is this "habbit" did infect very likely hundreds of US farm animals with H5N1...further spreading H5N1-creating new recombinations/variants and increasing risks of H5N1 in pigs...Do US pigs also "eat" poultry litter ? Is the US government stopping that H5N1 spread via poultry litter ??? --------- Human H5N1 risks may be highest in SE Asia... [url]https://www.thailandmedical.news/news/news-of-cats-dying-from-h5n1-in-texas-raises-alarms-as-dairy-cows-and-even-a-human-have-already-been-infected-with-the-new-strain[/url] or https://www.thailandmedical.news/news/news-of-cats-dying-from-h5n1-in-texas-raises-alarms-as-dairy-cows-and-even-a-human-have-already-been-infected-with-the-new-strain DJ-H5N1 spread in US cows -if linked to poultry litter-feeding cows with -possibly infected- chicken "residu"-may be contained. One may hope poultry litter and US pigs "did NOT mix"...is there any testing in pigs eating poultry litter ??? Farm pets but also rats, mice, may be another story...A lot of farm cats are half wild...Death cats-possibly infected-may be eaten by other animals spreading -possibly- a "cat H5N1".... -Lots of H5N1 infections with no or only mild symptoms -in humans/mammals- will be missed, -CoViD -but also measles- does decrease immunity for other diseases. -A-symptomatic spread may be a main driver starting a pandemic For that matter it would be welcome to know how many H5N1 infections result in a/mild symptoms...if 95% of (human) infections would stay under the radar-only 5% get "serious symptoms" only 1-in-20 H5N1 infections may be noticed...All the time H5N1 may pick up new mutations... Again-we are NOT YET in a H5N1 pandemic but we are much to close to it... |
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Dutch Josh
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[url]https://www.telegraph.co.uk/global-health/science-and-disease/chicken-waste-fed-to-cattle-may-be-behind-bird-flu-outbreak/[/url] or https://www.telegraph.co.uk/global-health/science-and-disease/chicken-waste-fed-to-cattle-may-be-behind-bird-flu-outbreak/ ; Poultry litter is not only cheaper than other food sources like soy and grains but is also more calorie-dense, meaning farmers can bulk up their herds much more quickly. - According to previous statements by the FDA, the practice is safe: “With respect to pathogenic microorganisms, drug residues and contaminants in poultry litter, FDA is not aware of any data showing that the use of poultry litter in cattle feed is posing human or animal health risks that warrant restrictions on its use,” the agency previously noted. DJ If poultry litter is "good and safe food" for cows-it will be also be used in pigs... There are several other theories on how the H5N1-infected cattle – so far identified in Texas, Idaho, Kansas, Ohio, New Mexico, and Michigan – contracted the virus. Many experts argue that the most likely route of infection is via wild birds – which have been found dead on some farms. “The spread of this around the world comes back to wild and wild bird populations and where they land and where their faeces goes,” stressed the WHO’s Dr Johsua Mott. DJ...yet no other country so far detecting H5N1 in cows...It is a US issue... “At some point, the contact with wild birds in the environment produced virus that then the cows had exposure to, but how that exposure happened is what many people are trying to figure out,” he added. It is also unclear if the virus is spreading from animal to animal, said Dr Mott. On each farm, multiple creatures have been infected but this could be because they are eating from a common source of infection – feed or wild birds – rather than passing it on to another. The director of ruminant health for the United States Department of Agriculture, Mark Lyons, suggested at a meeting last week the virus could be potentially transmitted by contamination of workers’ clothing, or the suction cups that are attached to cow udders during milking. However, others argue that poultry litter as a potential source of contamination cannot be ruled out. DJ, again...why -at least so far- only in the US ????? “The flu can be spread by faecal-oral routes, and so it’s not an impossible scenario that chickens who are infected with H5N1 are shedding live virus through faces, which the cattle then consume, and so it is a potential mechanism of transmission, although there are other explanations,” said Dr Brian Ferguson, Professor of Infectious Diseases at the University of Cambridge. “The BSE scandal showed us the reality of what happens when biosecurity is not a priority, and showed us that it really does need to be prioritised – which is not always the case, because of the economics involved,” he added. Despite large-scale culling in poultry flocks during outbreaks to limit spread, it seems a similar approach will not be taken for cattle. The CDC has advised farmers with affected herds to dispose of milk produced by infected cattle, although it is thought that the pasteurisation process also destroys the virus – meaning the risk to humans consuming animal products remains low. DJ, If you can not rule out cow-to-cow spread why H5N1-infected cows are not isolated ???? If I get it correct they end up with other ill cows...possibly further spreading H5N1 ... DJ, Texas may be to warm in summer so "cows move north" in spring... [url]https://publicdashboards.dl.usda.gov/t/MRP_PUB/views/VS_Avian_HPAIConfirmedDetections2022/HPAI2022ConfirmedDetections?%3Aembed=y&%3AisGuestRedirectFromVizportal=y[/url] or https://publicdashboards.dl.usda.gov/t/MRP_PUB/views/VS_Avian_HPAIConfirmedDetections2022/HPAI2022ConfirmedDetections?%3Aembed=y&%3AisGuestRedirectFromVizportal=y (following H5N1 in the US ?) [url]https://en.wikipedia.org/wiki/List_of_mammals_that_can_get_H5N1[/url] or https://en.wikipedia.org/wiki/List_of_mammals_that_can_get_H5N1 [url]https://en.wikipedia.org/wiki/1889%E2%80%931890_pandemic#Outbreak_and_spread[/url] or https://en.wikipedia.org/wiki/1889%E2%80%931890_pandemic#Outbreak_and_spread ; Most likely the first outbreak of Russian flu occurred in Western Siberia – Tomsk province. It was preceded by an epizootic of pneumonia in cattle.[6] DJ, Some "promote" the "suggestion" that the Russian Flu of 1889-90 was "corona linked"-wishfull thinking limiting the present CoViD-19 pandemic....Very likely the Russian Flu may have cow links....Further underlining the need to keep H5N1/infectious diseases in cows limited !!! Cows can get "D-flu" -risk for "A /B flu" was supposed to be very limited-wishfull thinking and lack of historic data may result in not knowing all the risks... |
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Dutch Josh
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DJ, A "good" reason would be to find out what animals get "poultry litter"...Can it explain (all) cases of H5N1 in US cows...If so-why was it allowed ???? [url]https://afludiary.blogspot.com/2024/04/offlu-statement-on-hpai-in-cows.html[/url] or https://afludiary.blogspot.com/2024/04/offlu-statement-on-hpai-in-cows.html ; The USDA has added 5 more outbreaks of HPAI H5 to their list (2 in Texas, 2 in New Mexico, 1 in Michigan), although the number of states reporting outbreaks remains at 6. Since testing remains on a voluntary basis - and currently only symptomatic dairy cows are recommended for testing - we've no idea how widespread the virus really is.
While there are legitimate logistical problems inherent in widespread testing (see discussion here), this is a situation where ignorance is far from bliss. We can hope that cows are a dead-end host, and that dairy cows will clear the virus in a few weeks and return to production, but no one really knows what the long-term impact of HPAI in cattle will be.
From a public relations standpoint, I understand their motivation, but simply calling is something `less scary' doesn't change the threat. Somewhat surprisingly, I'm seeing some state agriculture departments already adopting this nomenclature. As far as I know, it is still the purview of WOAH to name animal diseases, so unless or until they change their naming conventions, I'll continue to use HPAI. Yesterday, OFFLU - the WOAH/FAO joint network of expertise on avian influenza - published a brief update on HPAI in cattle (see below). While it doesn't add a lot we haven't already seen, it illustrates how seriously they take these developments. -- While it isn't clear yet how big of a deal HPAI in cattle really is, we are obviously entering new territory. If cattle, and goats can be infected, then there is reason to believe other types of livestock may be at risk as well.
Which means we need to be willing to test far more aggressively, across a wider range of susceptible animals, if we hope to stay ahead of this evolving threat. DJ, ....could poultry litter be used to feed pigs in the US - if not why not ? My "fear" is H5N1 may be also be in US pigs... So "cover it up"? " Saving "the economy".... Again-NO reports -so far- from outside the US of cows with H5N1. Poultry litter may be seen in many places as high risk-given that H5N1 in poultry is a "major problem"...So is the US the only (important) country using poultry litter as food for cows... IF...a very major "IF" poultry litter may have resulted in lots of farm animals (cattle, pigs, sheep) getting H5N1 there may be a food problem... Eggs was already an issue, inflation is a major problem...so -the last thing needed- is widespread H5N1 in farm animals... It does worsen pandemic perspectives... I learned something today. POTUS45 eliminated the Garbarge Feeding Regulations in the Swine Health Protection Act (SHPA) with the 2018 Farm Act. More self-regulated now if you didn't immediately guess the Garbarge Feeding amendments. #H5N1 https://federalregister.gov/index/2019/agriculture-department --- DJ, the problem is much larger than just US cows... |
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Dutch Josh
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- DJ...the "good news" is the US at least did NOT (yet) stop testing cows/cattle for H5N1.... [url]https://www.express.co.uk/news/world/1886815/bird-flu-student-dies-cough-vietnam[/url] or https://www.express.co.uk/news/world/1886815/bird-flu-student-dies-cough-vietnam ; A student has died just days after developing a cough that was being caused by a bird flu. It was a highly pathogenic strain of the virus already detected in the UK and the US. The 21-year-old from Vietnam is confirmed to have been infected with avian flu strain H5N1. While its most widespread targets are birds, the illness can be transferred to mammals and humans. People who had been in close contact with the student are being "monitored daily" in case they fall ill. Vietnam has also recorded its first human case of the less deadly H9 avian flu in a 37-year-old male. Despite being less severe than H5N1, the man fell ill on March 6 and was hospitalised a week later with pneumonia. Last month, Brits were urged to avoid close contact with wild birds and maintain a social distance of at least two metres due to fears of a new pandemic. DJ...the reporting MIGHT be wrong...there are several "clades" of H5N1...SE Asia may have a different clade of the same virus (just like the Mpox now spreading in Congo/DRC is worse then the Mpox showing up recently around the globe...JN.1 CoViD has very many subvariants... The world is complicated-bad reporting is NOT helping ! On "poultry litter" allowed in the US since 2018 to feed lots of farm animals...Very likely ALSO pigs.... DJ-CoViD-pandemic, Mpox both are NOT over...just "out of the news"....New strains of CoViD see increase of cases in many places...ignored by "media" to "save the economy"... [url]https://afludiary.blogspot.com/2024/04/north-carolina-reports-hpai-in-dairy.html[/url] or https://afludiary.blogspot.com/2024/04/north-carolina-reports-hpai-in-dairy.html [url]https://flutrackers.com/forum/forum/local-regional-communities-and-organizations/cidrap/988485-cidrap-avian-flu-detected-in-north-carolina-dairy-herd[/url] or https://flutrackers.com/forum/forum/local-regional-communities-and-organizations/cidrap/988485-cidrap-avian-flu-detected-in-north-carolina-dairy-herd and other "alternative media" have to do most of the research/reporting with twitter/X also -still- open for information... |
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Dutch Josh
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- "Because this infection in cattle is not the same as highly pathogenic avian influenza (HPAI), ... the AABP will now refer to this as Bovine Influenza A Virus (BIAV)," Bovine Veterinarian DJ, BIAV=H5N1 ! [url]https://afludiary.blogspot.com/2024/04/ajvr-virus-is-out-of-barn-emergence-of.html[/url] or https://afludiary.blogspot.com/2024/04/ajvr-virus-is-out-of-barn-emergence-of.html ; While governments and agencies are quick to reassure that HPAI H5 poses only a low risk to public health - which appears to be true, at least for the time being - a lot of experts are legitimately worried by the unprecedented moves the virus has made over the past 3 years.
The default position of many governments and agencies is to deny that a novel virus poses a specific threat, until there is definitive proof that it does. Hence, it took weeks before China admitted SARS-CoV-2 could transmit from human-to-human, and the debate raged globally for months over COVID's ability to reinfect individuals, or to spread via aerosols (yes, on both counts).
Even today, beeves (adult cattle used for food) aren't being routinely tested for HPAI, and only limited testing of `symptomatic' dairy cows is currently recommended (see USDA Testing Recommendations for Influenza A in Cattle).
To be fair, there are limited resources available for testing, and literally tens of millions of heads of potentially vulnerable livestock in this country. There are rules, frameworks, and a myriad of legal precedents under which agencies must work, and bureaucratic change often comes slowly.
All of which brings us to a cautionary report from the American Journal of Veterinary Research, which goes into the history of HPAI (and LPAI) viruses, and examines the risks posed by increasing spillovers into mammalian species (including pigs). - Although we've stood on the precipice before with H5N1 (see here, here, and here), only to have the threat recede, this time `feels' different. We are dealing with far more genotypes of the virus than we've ever seen before, and a very nearly global spread of the virus.
We could get lucky, and H5N1 fizzles. But even if we do, nature has a toolbox full of other novel flu subtypes with which to tinker. At some point our luck will run out. Anything we can learn now about how H5N1 is spreading in mammals can only help us in the future. DJ, there are "rapid tests" for H5N1 in birds...(maybe also of use in cows ?) - - [url]https://www.resource-online.nl/index.php/2024/04/04/bird-flu-virus-in-american-cows-and-one-person-reason-to-stay-alert/?lang=en[/url] or https://www.resource-online.nl/index.php/2024/04/04/bird-flu-virus-in-american-cows-and-one-person-reason-to-stay-alert/?lang=en DJ april 4 article-before "poultry-litter" showed up... |
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We cannot solve our problems with the same thinking we used when we created them.
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Dutch Josh
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DJ Also in NL "we" are looking at H5N1 in -so far only- US cows... [url]https://www.latimes.com/environment/story/2024-04-14/nobody-saw-this-coming-california-dairies-scramble-to-guard-herds-against-bird-flu[/url] or https://www.latimes.com/environment/story/2024-04-14/nobody-saw-this-coming-california-dairies-scramble-to-guard-herds-against-bird-flu ; “Nobody saw this coming,” said Michael Payne, a researcher and outreach coordinator at the Western Institute of Food Safety and Security at UC Davis. DJ...feeding cows-most likely even pigs "poultry-litter" with H5N1 widespread in birds of course is totally insane ! It may also explain why other countries do NOT report/see H5N1 in cows... [url]https://afludiary.blogspot.com/2024/04/microorganisms-case-report-on.html[/url] or https://afludiary.blogspot.com/2024/04/microorganisms-case-report-on.html ; While we await further developments surrounding the spread of HPAI H5N1 in American livestock, we have a follow up report from last summer's outbreak of H5N1 in Poland, which affected dozens of cats across multiple provinces (see Eurosurveillance: Two Papers On HPAI H5N1 clade 2.3.4.4b virus in cats, Poland, June to July 2023).
While cats appear to be particularly susceptible to avian influenza viruses (see here, here, and here), dogs have occasionally been infected as well.
There have been a few notable exceptions, including the following report from Canada's Food Inspection Agency last year: Domestic dog tests positive for avian influenza in Canada -- In summer 2023, during an outbreak of highly pathogenic avian influenza (HPAI) in cats in Poland, a 16-year-old dog was presented to the veterinary clinic with persistent, debilitating, dry cough, submandibular lymphadenomegaly, mild serous nasal discharge, and left apical heart murmur. A preliminary diagnosis of kennel cough was made and the treatment with amoxicillin/clavulanic acid and dexamethasone was initiated. Due to the lack of improvement within 2 days, a blood check-up, thoracic radiography and ultrasonography, and echocardiography were performed. Moreover, a rapid test for orthomyxovirus type A antigen in a throat swab was carried out and proved positive. The result was verified using RT-qPCR, which yielded a positive result for A/H5N1 influenza virus and negative results for A/H1N1, A/H3N2, type B influenza, and SARS-CoV-2. This case indicates that HPAI should be considered as a differential diagnosis not only in cats, but also in dogs with upper respiratory tract disease, particularly in regions experiencing A/H5N1 avian influenza outbreaks. ----- While the risk that your pet will be infected with H5N1 is still believed quite low, given what we've seen over the past couple of years, it does appear to be increasing over time.
-- As a general precaution, people should avoid direct contact with wild birds and observe wild birds only from a distance, whenever possible. People should also avoid contact between their pets (e.g., pet birds, dogs and cats) with wild birds. Don’t touch sick or dead birds, their feces or litter, or any surface or water source (e.g., ponds, waterers, buckets, pans, troughs) that might be contaminated with their saliva, feces, or any other bodily fluids without wearing personal protective equipment (PPE). DJ, there are lots of "death meat" products for dogs (dried pig-ears, bones etc) ...both dogs and cats can get in contact with infected birds...One can keep a cat indoors...a dog "has to do his thing" outdoors... The MAIN REASON !!! (my view) H5N1 now is spreading in farm animals and pets is outright human stupidity ! You do NOT feed pets raw meat if it may come from infected birds... [url]https://flutrackers.com/forum/forum/canada/h5n1-tracking-ag/nova-scotia-aa/988784-nova-scotia-avian-flu-in-mammals-2024[/url] or https://flutrackers.com/forum/forum/canada/h5n1-tracking-ag/nova-scotia-aa/988784-nova-scotia-avian-flu-in-mammals-2024
[url]https://flutrackers.com/forum/forum/canada/h5n1-tracking-ag/prince-edward-island-aa/941485-prince-edward-island-2022-2024-h5n1-in-wild-birds-and-mammals[/url] or https://flutrackers.com/forum/forum/canada/h5n1-tracking-ag/prince-edward-island-aa/941485-prince-edward-island-2022-2024-h5n1-in-wild-birds-and-mammals We report additional cases of highly pathogenic avian influenza Fully Eurasian H5N5 (2.3.4.4b) virus in raccoons from Nova Scotia and Prince Edward Island. Outbreaks are reported by province/territory. The geographical marker is on the capital. For detailed and current information on high pathogenicity avian influenza cases in wildlife, please consult : http://www.cwhc-rcsf.ca/avian_influenza.php. DJ, H5N5 spreading in wild animals in Canada may result in new mix of high risk flu-types for humans...(Can mammals catch both H5N5 and H5N1 ? And human types of flu-at the same time ? Very likely ! Creating even more oppertunities for new high risk variants !) CoViD is NOT over ! CoViD, measles (a.o.) do decrease immunity protection against other infections...so with H5N1 being widespread in "nature" human protection against H5N1 is getting less ! [url]https://www.wormsandgermsblog.com/2024/04/articles/animals/other-animals/h5n1-in-dairy-cattle-april-11-2024-update/[/url] or https://www.wormsandgermsblog.com/2024/04/articles/animals/other-animals/h5n1-in-dairy-cattle-april-11-2024-update/ ...ignoring completely poultry litter/only H5N1-cases in US cows... and DJ, [url]https://en.wikipedia.org/wiki/Mastitis[/url] or https://en.wikipedia.org/wiki/Mastitis infection of the udder is a main sign of H5N1...after "Bovine Flu" we now get another wordgame ? DJ...if we treat farmanimals like "production-machines" we are asking for lots of problems...Re-think food production, stop fur-farms ! We are doing all we can to get a flu-pandemic on top of the not-over CoViD pandemic ! |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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[url]https://twitter.com/RickABright/status/1780475028817039802[/url] or https://twitter.com/RickABright/status/1780475028817039802 ; Grateful for to finally share some #H5N1 flu virus sequences from a few of the cats in the ongoing / widespread outbreak in the food supply across the US (dairy, poultry) Very oddly, they have chosen to hide the location of infected cats and when viruses were collected. No data on how many infected cats have been found, are these representative or hand selected? No cow sequences shared, even though they’ve been sequencing many (and attempting to analyze sequences) Makes me wonder, how long has this outbreak been going on? Why are they intentionally withholding certain metadata and epi data? When will they be transparent about the extent of the outbreak and the risk to human food supply, commerce, and potentially even public health? The lack of transparency is very troubling. We’ve seen before that lack of transparency erodes public trust and has a hugely negative impact on collaboration and cooperation when it’s most critical. We can do better. - My guess (unfortunate we have to guess) is that those 9 feline sequences are from the sick/dead cats from the TX dairy farms b/c added guidance for vets evaluating/ handling potentially exposed cats: https://cdc.gov/flu/avianflu/veterinarians-handling-cats.htm… #H5N1 #HPAI #AvianFlu DJ.."sharing info to hide info"... DJ-and again "still only in the USA"... [url]https://www.thailandmedical.news/news/no-agency-is-prepared-existing-h5n1-vaccines-and-antivirals-like-tamiflu-and-xofluza-do-not-work-against-the-new-h5n1-variants[/url] or https://www.thailandmedical.news/news/no-agency-is-prepared-existing-h5n1-vaccines-and-antivirals-like-tamiflu-and-xofluza-do-not-work-against-the-new-h5n1-variants DJ-We may be finding/detecting more cases-more testing...it may NOT mean H5N1 (still) is increasing...we only are looking more=finding more... [url]https://afludiary.blogspot.com/2024/04/cdc-guidance-for-veterinarians.html[/url] or https://afludiary.blogspot.com/2024/04/cdc-guidance-for-veterinarians.html ; In late March and early April 2024, Texas reported detection of HPAI A(H5N1) in several cats from several dairy farms experiencing HPAI A(H5N1) virus infections in dairy cows, suggesting the virus spread to the cats either from affected dairy cows, raw cow milk, or from wild birds associated with those farms. - While cat-to-human transmission of influenza viruses has only rarely been documented, HPAI H5 continues to exceed our expectations, and some extra precautions are warranted. DJ, H5N1 in cats may be another story than H5N1 in cows/catles...Cats "can go anywhere"...risks are much higher for cat-spread of H5N1... Agricultural and health officials monitor Bird flu's spread to Michigan dairy herds. WKAR Public Media | By Wali Khan Published April 16, 2024 at 3:54 PM EDT State agriculture officials say experts across the nation are assessing the avian influenza outbreak among dairy herds. The virus has been reported in herds in Ionia, Isabella, Ottawa, and Montcalm counties. Each herd is estimated to be more than 500 animals. The first infection was traced to Texas, where the virus is also being detected in herds. The flu virus is being monitored on the “federal, state and local” level, according to State Veterinarian Nora Wineland. “We've identified additional suspected cases and those were reported to and are by local veterinarians, and producers and samples were submitted to the Michigan State University Veterinary Diagnostic Lab for testing." Wineland said the pattern of reporting and testing is expected to continue, “leading to the potential for more cases to be identified in the future.”... |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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[url]https://www.biorxiv.org/content/10.1101/2024.04.16.588916v1[/url] or https://www.biorxiv.org/content/10.1101/2024.04.16.588916v1 ; AbstractThe global emergence of highly pathogenic avian influenza (HPAI) A (H5N1) clade 2.3.4.4b viruses poses a significant global public health threat. Until March 2024, no outbreaks of this virus clade had occurred in domestic cattle. We genetically characterize HPAI viruses from dairy cattle showing an abrupt drop in milk production. They share nearly identical genome sequences, forming a new genotype B3.13 within the 2.3.4.4b clade. B3.13 viruses underwent two reassortment events since 2023 and exhibit critical mutations in HA, M1, and NS genes but lack critical mutations in PB2 and PB1 genes, which enhance virulence or adaptation to mammals. The PB2 E627K mutation in a human case underscores the potential for rapid evolution post-infection, highlighting the need for continued surveillance to monitor public health threats. DJ...in other words "H5N1 is on the move"... [url]https://southdakotasearchlight.com/2024/04/17/two-veterinarians-hundreds-of-miles-apart-solved-a-cow-sickness-whodunit/[/url] or https://southdakotasearchlight.com/2024/04/17/two-veterinarians-hundreds-of-miles-apart-solved-a-cow-sickness-whodunit/ ; It appeared to be a problem with the food. In February, dairy cattle in multiple herds in northern Texas were suddenly producing less milk, and what they gave was abnormal and thick. And the typically voracious eaters had seemingly lost their appetites. For weeks in March, veterinarian Dr. Barb Petersen sought an answer. She talked to dairy owners and exchanged notes with fellow vets in the panhandle of Texas. She submitted numerous samples to labs that tested for more than 200 potential causes. - When the voluminous amount of testing in Texas failed to find any clues, Magstadt and Petersen concluded that a likely cause was ill-made food. “The affected cattle were very high-producing dairy cows, and they are on a race-car ration,” Magstadt said. “If you mess with that a little bit, it can cause problems.” Petersen agreed to send Magstadt some samples of the feed and animals for testing. But then the cats started dying. Barn cats are common on farms. They kill rodents, provide companionship and need little help to survive. Some dairy farmers also feed them milk from their cows, and sick cows can shed viruses in their milk. “A colleague of mine, he told me, ‘You know what’s strange? I went to one of my dairies last week, and all their cats were missing. I couldn’t figure it out — the cats usually come to my vet truck,’ ” Petersen recalled. “And then someone called me and said half of his cats had passed away without warning, and so then all the alarm bells start going off in your head.” The cats had died from swollen brains, a potential result of influenza. They didn’t have rabies. - Yet Magstadt immediately tested Petersen’s milk samples for influenza A — which most commonly infects birds — before investigating the feed. He thought the testing would merely rule out bird flu as a potential cause, but instead it confirmed it. “I was incredibly surprised,” Magstadt said. Further testing and retesting over days confirmed that the virus is the type that has been driving the poultry outbreaks, with an official confirmation on March 25. The initial affected herds were in northern Texas and southwest Kansas, according to the U.S. Department of Agriculture. Since then, infected cattle have been discovered in far flung states, including South Dakota, often the result of infected cattle being transported to new herds. DJ..."poultry litter" as food for farm animals is not mentioned... while the problem only is growing... [url]https://afludiary.blogspot.com/2024/04/aphisusda-updated-faq-on-detection-of.html[/url] or https://afludiary.blogspot.com/2024/04/aphisusda-updated-faq-on-detection-of.html ; I greatly appreciate the APHIS/USDA refusal to re-brand HPAI H5N1 as the industry promoted kinder-and-gentler BIAV (Bovine Influenza A Virus), but we are now a full three weeks since the first positive tests for HPAI in cattle (which took far too long to be performed), and still we have disappointingly little in the way of solid information on exactly how this virus is spreading, or how wide-spread it really is.
The beef/dairy industry and government agencies are understandably keen to reassure the public of the safety of the food supply, and the very low risk to human health from infected cattle. But bland reassurances, repeated without accompanying evidence, soon loses its powers of persuasion. - DJ...the claim poultry litter to feed farm animals is spreading H5N1 is ignored... [url]https://en.wikipedia.org/wiki/Poultry_litter#Use_as_cattle_feed[/url] or https://en.wikipedia.org/wiki/Poultry_litter#Use_as_cattle_feed ; In December 2003, in response to the detection of bovine spongiform encephalopathy (mad cow disease) in a cow in the state of Washington, the FDA announced plans to put in place a poultry litter ban. Because poultry litter can contain recycled cattle proteins as either spilled feed or feed that has passed through the avian gut, the FDA was concerned that feeding litter would be a pathway for spreading mad cow disease. In 2004, FDA decided to take a more comprehensive approach to BSE that would remove the most infectious proteins from all animal feeds. The FDA decided at this point that a litter ban was unnecessary in part based on comments by the North American Rendering Industry.[8] In 2005, the FDA published a proposed rule that did not include a litter ban and in 2008 the final rule did not include the ban either. DJ...so H5N1 seems to be only a problem in US cattle - very likely linked to using In agriculture, poultry litter or broiler litter is a mixture of poultry excreta, spilled feed, feathers, and material used as bedding in poultry operations -only in the US !- to feed cows, pigs etc...for economic reasons- profit first- IS VERY LIKELY spreading H5N1 -still !!!- in US farm animals... DJ- I am not any kind of expert...but why does the US continue feeding farm animals chicken "droppings" when H5N1 seems to be spreading now from cattle back to poultry ??? Is the US still in the middle ages ? Does the US health experts realize how virus spread ? [url]https://www.thailandmedical.news/news/h5n1-circulating-in-dairy-cows-and-cats-in-america-are-a-new-strain-b3-13-belonging-to-clade-2-3-4-4b-that-underwent-reassortment-events[/url] or https://www.thailandmedical.news/news/h5n1-circulating-in-dairy-cows-and-cats-in-america-are-a-new-strain-b3-13-belonging-to-clade-2-3-4-4b-that-underwent-reassortment-events DJ...this is crazy ! |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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[url]https://www.wur.nl/en/about-wur/news-wur/show/probably-multiple-transmission-routes-involved-in-2023-spread-of-bluetongue.htm[/url] or https://www.wur.nl/en/about-wur/news-wur/show/probably-multiple-transmission-routes-involved-in-2023-spread-of-bluetongue.htm describing how long(er) distance transport contributed to spread of Blue Tongue Virus Disease (BTV-D)... Both BTV and H5N1 may infect without much symptoms...only testing symptomatic animals is missing those without symptoms... [url]https://www.sbs.com.au/news/article/why-theres-enormous-concern-over-the-risk-of-bird-flu-spreading-to-humans/kcze6zb7y[/url] or https://www.sbs.com.au/news/article/why-theres-enormous-concern-over-the-risk-of-bird-flu-spreading-to-humans/kcze6zb7y ; The World Health Organization has voiced alarm at the growing spread of H5N1 bird flu to new species, including humans, who face an "extraordinarily high" mortality rate. "This remains I think an enormous concern," the UN health agency's chief scientist Jeremy Farrar told reporters in Geneva. The current bird flu outbreak began in 2020 and has led to the deaths of tens of millions of poultry, with wild birds also infected as well as land and marine mammals. What do we know about the H5N1 variant?Cows and goats joined the list last month — a surprising development for experts because they were not thought susceptible to this type of influenza. DJ..of course [url]https://en.wikipedia.org/wiki/Poultry_litter#Use_as_cattle_feed[/url] or https://en.wikipedia.org/wiki/Poultry_litter#Use_as_cattle_feed feeding cattle with (infected) poultry "droppings" exposes cattle to high viral loads of H5N1... Both increase of testing and replacing "poultry litter" to feed farm animals does increase costs..."Saving the economy" AGAIN at the costs of (longer term) human/public health... DJ-If we keep failing to get our priorities right we are -again- creating another pandemic ON TOP OF CoViD ! Humans are selfdestructive...at least "blind capitalism" is self destructive..."Age of stupid"... |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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[url]https://www.latimes.com/environment/story/2024-04-18/avian-flu-outbreak-raises-a-disturbing-question-is-our-food-system-built-on-poop[/url] or https://www.latimes.com/environment/story/2024-04-18/avian-flu-outbreak-raises-a-disturbing-question-is-our-food-system-built-on-poop The federal government does not regulate poultry litter in animal feed, and in many states — including Missouri, Alabama and Arkansas — there are no requirements or regulations regarding contamination or processing. “The FDA may take regulatory action if it becomes aware of food safety concerns with poultry litter products intended for use in animal food in interstate commerce,” Pfaeffle said in the statement from both the USDA and FDA. An online guide from the University of Missouri notes there are “no federal or Missouri regulations governing the use of poultry litter as a feed.” However, the guide’s authors urge users to employ “common sense.” “Poultry litter should not be fed to dairy cattle or beef cattle less than 21 days before slaughter,” the guide notes, citing concerns about “residues of certain pharmaceuticals.” Most other developed nations — including Canada, the United Kingdom and the countries within the European Union — have banned the practice. The FDA considered doing so in the U.S. in the mid-2000s. For cattle farmers, the waste — which includes calcium, zinc and other minerals and vitamins — provides a cheap form of protein feed. For poultry farmers, the exchange allows them to divert the litter away from a landfill or from being burned. In the 1980s, concerns about bovine spongiform encephalopathy — or mad cow disease — took hold across Europe, when cases of the incurable and invariably fatal neurodegenerative disease of cattle began to appear. The disease, which is caused by agents known as prions, can transfer to people who eat the meat of infected cattle. In people, the disease is fatal and called Creutzfeldt-Jakob disease. Just as cattle are fed poultry waste, chickens are often provided feeds that consist of cattle waste and renderings — creating a potential route for prions to re-enter the food supply. However, because the FDA mandates the removal of all tissues shown to carry the prions — such as brains and spinal cords — from poultry diets, the risk is reduced. However, other more common pathogens are also found in poultry litter. In one 2019 study of litter used on farm fields as fertilizer, researchers found that every sample tested from U.S. broiler chickens carried E. coli strains resistant to more than seven antibiotics — including amoxicillin, ceftiofur, tetracycline, and sulfonamide. It is unclear if the litter was heat treated before it was applied. Raudabaugh said all poultry litter feed in California is kiln heated and exposed to temperatures that can kill bacteria, such as E. coli, and viruses, including H5N1. “Firms are sampling and analyzing finished product for Salmonella regularly,” said Lyle, the state’s food and agriculture spokesman. He noted that poultry is regularly tested for bird flu and that poultry waste from a flock infected with bird flu “cannot leave the premises until it has met CDFA requirements for ensuring the virus has been eliminated,” he said. “The premises is also tested and the quarantine is not released until the premises tests negative for highly pathogenic avian influenza.” Lyle said cattle herds with “symptoms consistent” with bird flu infections “can be tested at the California Animal Health and Food Safety Laboratory in consultation with the CDFA Animal Health Branch.” He added that no symptomatic herds have been identified, “although one herd that lost pregnancies was tested and was negative” for the virus. DJ a few remarks; -H5N1 ONLY !!!! so far detected in US cattle...not outside the US...most countries will have done some testing... -Virusses may escape testing, may even survive "sterilization" so...to propper desinfect may end up making the product unuseable -So far there may not be any other logical explanation for H5N1 spread in US cows... [url]https://flutrackers.com/forum/forum/united-states/h5n1-tracking-af/florida/958326-florida-avian-influenza-detected-in-a-bottlenose-dolphin-recovered-in-march-2022[/url] or https://flutrackers.com/forum/forum/united-states/h5n1-tracking-af/florida/958326-florida-avian-influenza-detected-in-a-bottlenose-dolphin-recovered-in-march-2022 ; Article Abstract DJ...If you could -ad random- test mammals for H5N1 would 1-in a million mammals test positive ? One in ten-million ? Or would we find that 0,1% of susch large scale testing may find H5N1 ???? |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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[url]https://www.nytimes.com/2024/04/19/health/bird-flu-usda-cattle.html[/url] or https://www.nytimes.com/2024/04/19/health/bird-flu-usda-cattle.html If one tests a-symptomatic cattle and still finds H5N1 in cows alarm bells start ringing... CDC: Protect Yourself From H5N1 When Working With Farm Animals; - Wash hands -Coveralls -Apron -Respirator -Safety goggles or face shield -Head cover or hair cover -Gloves -Boots DJ...maybe "we" should realize farm animals are living creatures...able to catch/spread diseases...Farm animals are NOT milk/meat producing machines ! DJ...if we would increase testing/preventative healthcare also in humans we may stop pandemics before they can start and "create" better lives ! Asymptomatic spread may be part of how pandemics start...and history is full of pandemics...(Very likely [url]https://en.wikipedia.org/wiki/List_of_epidemics_and_pandemics[/url] or https://en.wikipedia.org/wiki/List_of_epidemics_and_pandemics is only the tip of the iceberg...lots of diseases may have been "co-spreading"...Wishfull thinking has the Russian flu of 1889/90 as an early form of CoViD...but maybe a corona-cold virus did start then as a flu-co-infection ???) Replying to - - -!!!!!!!!!!!!!!!!! [url]https://afludiary.blogspot.com/2024/04/a-slight-case-of-deja-flu.html[/url] or https://afludiary.blogspot.com/2024/04/a-slight-case-of-deja-flu.html ; “History Doesn't Repeat Itself, but It Often Rhymes” – Mark Twain. #18,018 While the recent spillover of HPAI H5N1 into dairy cows in at least 8 states, and the discovery of `high concentrations' of the virus in raw milk, has been called unprecedented, it isn't that far afield from the events of a decade ago, when the MERS coronavirus was found to be endemic in Arabian camels, and shed in camel's milk and urine. DJ, like the Blue Tongue Virus-disease here in NL the REAL problem is to many farm animals...We urgently need to rethink the way we live ! Decrease meat consumption ! Although the outbreak in dairy cows has only been reported in 32 herds across 8 states so far, it is likely that some spillovers have not been documented. Testing is voluntary, and is normally limited to dairy cattle.
DJ, feeding "poop" to farm animals may be a US habbit; poultry eat cow-"droppings" -cattle eat poultry "droppings" high caloty and low cost...but it may be spreading diseases ! Somehow the US is in denial their "problem with feeding farm animals with eachothers "droppings" is not discussed... While heavily discouraged by most public health agencies (see CDC's Fast Facts: Why Is Raw Milk Unsafe?) there are enough loopholes in state laws that most American can buy raw milk if they want it.
In many other countries, however, the consumption of `raw milk' is much higher than in the US. The USDA reported in 2019: In Mexico, half of all fluid milk goes into the processing industry for the production of yogurt, cheeses, and other products. Between 40-45 percent of consumption is of fluid drinkable milk, such as pasteurized, ultra-high temperature processed (UHT), bottled, or packaged milk. Unpasteurized, raw milk accounts for between 5-10 percent of consumption. Beyond that, accurate estimates of the consumption of raw milk around the globe are hard to come by. But it is safe to say in that in some countries, that number is likely to greatly exceed 10%. So...raw milk may spread H5N1 in other mammals, insects may spread H5N1...cats/pets may do so...By now it is no longer "if" but "when" we see human-to-human spread of H5N1...The few things stopping that may be another form of flu able to spread even faster...
Or even more ominously, if we started seeing the virus turn up in domestic pigs. A year ago, the ECDC/EFSA Avian Influenza Overview December 2022 – March 2023 warned: The additional reports of transmission events to and potentially between mammals, e.g. mink, sea lion, seals, foxes and other carnivores as well as seroepidemiological evidence of transmission to wild boar and domestic pigs, associated with evolutionary processes including mammalian adaptation are of concern and need to be closely followed up. While it is always possible that there is some genetic barrier that prevents HPAI H5N1 from sparking a human pandemic, over the past 3 years the virus has greatly expanded its mammalian host range.
DJ, wishfull thinking by now has become a global risk in itself !!! START REDUCING RISKS BY REDUCING FARM ANIMALS NOW !!!!!!!!!!!! Vaccines may limit damage but can not stop/end pandemics ! Even sterilizing vaccines have limits...There are 8 billion people on this planet...with CoViD we did see record high usage of all kinds of vaccines ! DJ, CoViD, M-pox..."keep it out of the news/limit-stop testing"..."saving the economy/profits" in a self destructive way... |
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We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein |
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Dutch Josh
Adviser Group Joined: May 01 2013 Location: Arnhem-Netherla Status: Offline Points: 95977 |
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[url]https://www.statnews.com/2024/04/21/usda-releases-h5n1-bird-flu-genetic-data-eagerly-awaited-by-scientists/?utm_campaign=twitter_organic&utm_source=twitter&utm_medium=social[/url] or https://www.statnews.com/2024/04/21/usda-releases-h5n1-bird-flu-genetic-data-eagerly-awaited-by-scientists/?utm_campaign=twitter_organic&utm_source=twitter&utm_medium=social ; The U.S. Department of Agriculture, which has been under pressure from scientists both at home and abroad to share more data on the H5N1 bird flu outbreaks in dairy cows, uploaded a large number of genetic sequences of the pathogen late Sunday. Access to the 239 genetic sequences will help scientists assess whether the dangerous virus has acquired mutations that might make it easier for it to spread to and among mammals, and whether additional changes have been seen as it moves from cow to cow and herd to herd. In addition to virus sequences from cattle, the trove includes sequences of viruses retrieved from cats, chickens, a skunk, a racoon, a grackle, a blackbird, and a goose, the agency said. Rick Bright, a pandemic planning consultant who has been vocally critical of the USDA for being slow to share sequence data, noted the disclosure had “taken a long time.” “But I’m grateful,” he said of the government’s move. “And eager to see what we can discover.” - DJ, besides poultry litter H5N1 is also spreading (via aerosols ???) in lots of other mammals... The CDC is actually recommending full PPE for farm workers to prevent infections of H5N1. They also acknowledge the increased risk of more transmission to people and say they would change the risk assessment if person to person transmission were sustained but not if sporadic. DJ [url]https://en.wikipedia.org/wiki/Personal_protective_equipment[/url] or https://en.wikipedia.org/wiki/Personal_protective_equipment [url]https://www.barrons.com/articles/bird-flu-h5n1-human-vaccine-supply-f1f8c6e7[/url] or https://www.barrons.com/articles/bird-flu-h5n1-human-vaccine-supply-f1f8c6e7 ... DJ, the CoViD pandemic is NOT over...H5N1 may come on top of it...still sticking to "vaccines may save us" is absurd ! Reduce farm animals ! Clean air ! Surveillance for a potential zoonotic jump of bird flu using ER visits as a main source of data seems like a “little too late” strategy How about… I don’t know, asking the people on the farms where outbreaks have been detected to provide swabs on a routine basis. That would be an appropriate surveillance effort given the gravity of the situation DJ, "saving the economy" being put above public health is indicating insanity...Beyond criminal ! What does this mean?? From CDC H5N1 situation update: “Testing… is being done… using a CDC test, and CDC is conducting confirmatory testing…” This is the least descriptive wording I can imagine. “a CDC test” - is this a CDC Lab Developed test for H5N1? Is this a commercial test being performed at CDC? Is it even testing for H5N1? The incomplete nature of this makes it sound like whoever wrote the update has little understanding of what they are writing. CDC can do better… (right?) and DJ...age of stupid !!! I need a drink...no...no black coffee...a bottle of rum .....@#&%$*@(@!!!!!!!!!!!! |
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