Click to Translate to English Click to Translate to French  Click to Translate to Spanish  Click to Translate to German  Click to Translate to Italian  Click to Translate to Japanese  Click to Translate to Chinese Simplified  Click to Translate to Korean  Click to Translate to Arabic  Click to Translate to Russian  Click to Translate to Portuguese  Click to Translate to Myanmar (Burmese)

PANDEMIC ALERT LEVEL
123456
Forum Home Forum Home > Main Forums > Latest News
  New Posts New Posts RSS Feed - Scottish nurse rushed back to London for isolation
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Now tracking the new emerging South Africa Omicron Variant

Scottish nurse rushed back to London for isolation

 Post Reply Post Reply Page  12>
Author
Message
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Topic: Scottish nurse rushed back to London for isolation
    Posted: October 09 2015 at 1:40am
This is quite a turn up and concerning.

No details yet, but she was given the all clear last December, returned to work here in UK, and suddenly she gets systemically ill again 9 months later, and is found to have the virus AGAIN at detectable levels, some sort of reactivation of dormant virus. They had already checked her eye secretions, so it is not something they missed. Perhaps Ebola is not confined to acute phase but may display latent periods, and reactivation. Perhaps Ebola can become a chronic disease. The nurse has had thyroid and joint involvement over the last year. Beginning to raise possibility that survivors may not ever fully clear virus.

They are worried enough to trace close contacts of the nurse again and put them on follow up. Also she was flown to London via RAF Northolt, under maximum precautions for infection control. Here home is being decontaminated also. They do think it is not a danger to others. She met the Prime Ministers wife 10 days ago just before taking I'll.

Here is link and story below.


http://www.bbc.co.uk/news/uk-scotland-34483584

A Scottish nurse who contracted Ebola in Sierra Leone has suddenly been readmitted to an isolation unit in London following an "unusual late complication".

NHS Greater Glasgow and Clyde confirmed that the virus is again present in Pauline Cafferkey but left over from the original infection.

It is not thought to be contagious.

The 39-year-old, has been flown back the isolation unit at the Royal Free Hospital in London.

Ms Cafferkey spent almost a month in the unit at the beginning of the year after contracting the virus in December 2014.

NHS Greater Glasgow and Clyde said she had been admitted to the Queen Elizabeth University Hospital in Glasgow on Tuesday after feeling unwell and was treated in the infectious diseases unit.

She was transferred from Glasgow to the Royal Free Hospital in the early hours of the morning due to an unusual late complication in her illness.


Dr Emilia Crighton, NHSGGC director of public health, said: "Pauline's condition is a complication of a previous infection with the Ebola virus.
"The risk to the public is low. In line with normal procedures in cases such as this, we have identified a small number of close contacts of Pauline's that we will be following up as a precaution."
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 09 2015 at 2:24am

http://www.dailyrecord.co.uk/news/scottish-news/scots-ebola-nurse-pauline-cafferkey-6601299

The Royal Free said: "We can confirm that Pauline Cafferkey was transferred from the Queen Elizabeth University Hospital in Glasgow to the Royal Free London hospital in the early hours of this morning due to an unusual late complication of her previous infection by the Ebola virus.

"She will now be treated in isolation in the hospital's high-level isolation unit under nationally agreed guidelines.

"The Ebola virus can only be transmitted by direct contact with the blood or bodily fluids of an infected person while they are symptomatic so the risk to the general public remains low and the NHS has well established and practised infection control procedures in place."

Scotland's Chief Medical Officer Catherine Calderwood said: "

She added: "Pauline is now being cared for in the best place possible, with specialists who have the most experience of looking after patients who have previously recovered from the Ebola virus."

Dr Ben Neuman, lecturer in virology at the University of Reading, said he thought Ms Cafferkey's case was only the second one where Ebola is reported to have "reactivated".



"It is difficult to be certain of the outcome at this stage. The likelihood of spreading Ebola depends on how much of the virus is present in the blood. If her body was able to control the virus once, chances are she can do it twice.
Back to Top
Hazel View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazel Quote  Post ReplyReply Direct Link To This Post Posted: October 09 2015 at 4:21am

http://news.sky.com/story/1566472/british-ebola-nurse-in-a-serious-condition


Most recent press statement from The Royal Free says that the nurse is now in a serious condition, but not much more info yet



Back to Top
OriginalHappyCamper View Drop Down
Valued Member
Valued Member
Avatar

Joined: December 25 2013
Location: Silverton, Or
Status: Offline
Points: 2850
Post Options Post Options   Thanks (0) Thanks(0)   Quote OriginalHappyCamper Quote  Post ReplyReply Direct Link To This Post Posted: October 09 2015 at 5:37am
??? Ia this a relapse or continuation of he initial infection????
Jesus Christ died and was raised on the third day, the only "God" to overcome death.
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 09 2015 at 6:24am
Exactly but as we have no more information yet, we can't be sure. Last update on the hospital website was at midday so probably nothing else today.

The fact that they say the virus has become detectable AGAIN, the fact she is seriously ill, that contacts are now on follow up, seems to points to some sort of reactivation and replication event occurring in the patient.

The precautions mean she is being treated like an Ebola patient again so must fit the criteria for the security and isolation she is getting. I.e. she walked out of hospital, but returned in a bubble tent being flowen by Royal Air Force, so something happened between then and now.

Possibly virus reappeared from one of the immunoprivilaged sites we talked about before on the forum, like the eyeball, and the central nervous system. Not sure if this nurses case indicates a potential reservoir of the virus in survivors.

I think the following quote sums it up.

http://www.itv.com/news/2015-10-09/ebola-reactivating-may-have-caused-complications-for-british-nurse-pauline-cafferkey/

Julian Hiscox, professor of infection and global health at the University of Liverpool, hit the nail on the head with the following:

"Due to the sheer scale of this outbreak compared to previous ones, we are going to see many aspects of Ebola virus infection that we have not observed before.

Back to Top
Jen147 View Drop Down
Moderator
Moderator
Avatar

Joined: March 23 2013
Status: Offline
Points: 17144
Post Options Post Options   Thanks (0) Thanks(0)   Quote Jen147 Quote  Post ReplyReply Direct Link To This Post Posted: October 09 2015 at 12:29pm
British nurse who contracted Ebola hospitalized again

Oct 9th 2015

LONDON (AP) — A British nurse who recovered from Ebola last year has been hospitalized again for treatment of an unusual late complication, London's Royal Free Hospital said Friday.

Pauline Cafferkey was being treated in the hospital's isolation unit and her condition was described as serious.

Ben Neuman, a virologist at the University of Reading, said, Cafferkey's case appeared unusual because of the stubborn persistence of the Ebola virus in her body. In a similar case detected in an American doctor, Ebola was found in his left eye months after he recovered.

Cafferkey was flown to London early Friday from Scotland, where she lives.

Medical authorities say the risk of Cafferkey transmitting the virus is low, but public health officials in Scotland are monitoring people with whom she had close contact. Ebola is transmitted by direct contact with blood or body fluids.

Cafferkey was diagnosed with Ebola in December after returning from Sierra Leone. She was treated at the Royal Free for several weeks and discharged in January.

Cafferkey was honored at the Pride of Britain Awards in London last month and met with Prime Minister David Cameron's wife, Samantha, at 10 Downing St.

The prime minister tweeted that he wished Cafferkey "a quick recovery."

Since Ebola broke out in Guinea's forest region last year, it has killed more than 11,200 people in West Africa.

Experts say there is mounting evidence that the mental and physical health problems in Ebola survivors can last for years after the virus is cleared from the bloodstream. There are thousands of Ebola survivors in West Africa suffering from long-term side effects of the disease, many of whom have no access to treatment.

http://www.aol.com/article/2015/10/09/british-nurse-who-contracted-ebola-hospitalized-again/21247222/?icid=maing-grid7%7Cmain5%7Cdl2%7Csec1_lnk2%26pLid%3D-903112831
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 11 2015 at 8:32am
Possible the unthinkable is happening and the nurse may have full blown Ebola again.

Papers up here in Scotland saying she went to local out of hours medical services on Monday night, She is reported as saying she was feeling very ill vomiting ( felt like she had Ebola again). There she was told it was just a stomach norovirus, and sent home. ( Like what happened to Mr Duncan ). Once home she quickly got worse, so went to local A&E.

Think the lack of comments from the Royal Free is because they are not sure what is happening.

Is it norovirus weakening her immune system and letting the ebola virus replicate again, or has the Ebola caused the illness directly. So does she have stomach virus and Ebola detected is just an artifact finding, or is she an infectious Ebola patient again.

It is very confusing and potentially a huge worry. They are saying it is a rare situation, but in truth very few European people have ever had Ebola, and what is seen in African genotypes may not be the same in Caucasian populations. What happens if your US survivors start getting sick again, or worse become infectious again ?????

This woman has been cured 9 months ago, she was visiting a primary school on Monday, and by Monday night she gets sick, by Tuesday testing positive for Ebola and in isolation.

Her family have blasted the national health service Here is what they are saying.


http://www.bbc.co.uk/news/uk-scotland-34499608
Family of Ebola nurse Pauline Cafferkey says she was 'let down'

Cafferkey told the Sunday Mail that her sister had gone to a GP out-of-hours clinic at the Victoria Hospital in Glasgow on Monday night but the doctor who assessed her diagnosed a virus and sent her home.

She said: "At that point me and my family believe they missed a big opportunity to give the right diagnosis and we feel she was let down. Instead of being taken into hospital, she spent the whole of Tuesday very ill.

"I think it is absolutely diabolical the way she has been treated... We don't know if the delays diagnosing Pauline have had an adverse effect on her health, but we intend to find out.

"It has not been good enough. We think there have been major failings and we just want her to pull through. This kind of recurrence seems to be rare but we don't yet know enough about it."


The mail say the nurse does have Ebola again and it took 4 days to diagnose.

Doctors sent home nurse with ebola FOUR days before she was put back into isolation unit: Pauline Cafferkey's family condemn 'absolutely diabolical' treatment and claim doctors 'missed a big opportunity' and told her she had a virus
Pauline Cafferkey, 39, visited clinic on Monday but was told she had virus
After being sent home for 4 days, she returned to doctors with symptoms
Now in isolation after being taken to hospital with Ebola for a second time
Family say doctors 'missed a big opportunity' to treat her and said it was 'absolutely diabolical' to miss symptoms despite first Ebola outbreak


Read more: http://www.dailymail.co.uk/news/article-3268278/Doctors-sent-home-nurse-ebola-FOUR-days-earlier-Pauline-Cafferkey-s-family-condemn-absolutely-diabolical-treatment-claim-doctors-missed-big-opportunity-told-virus.html#ixzz3oH5JEVIF


Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 11 2015 at 10:13am
Found a study from 2008. ( link at bottom)

In the study they found that infected cells can establish a persistent low-level infection of EBOV due to the induction of the IFN antiviral response. So the virus is kept in check, at extremely low levels, by the induction of IFN alpha and beta.

If however at a later date there is sufficient suppression of this antiviral response it causes a switch and reversal from a low-level infection to a more productive infection.

Here is the interesting bit. The suppression of the IFN antiviral response occurs when another inflammatory mechanism becomes more dominant. This is called stimulating the Ras/MAPK pathway.   It happens in allergy and autoimmunity as well as other immune responses.

In the study they heavily activated the ras/map kinase pathway as would normally be seen with autoimmunity and allergy, rather than transient infection.

So perhaps the nurse had Ebola under control, but has some sort of autoimmune condition which is skewing her immune responses away from antiviral to autoimmunity. Looking the ability to keep the virus dormant. It is just an idea as she reported having problems with her thyroid.

Many viruses can reactivate like chicken pox and shingles, Herpes Simplex Virus ( cold sores etc). It will be problematic if EBV turns out to be the same.

Just a thought though I am probably wrong.

Hzx

Ps
The second hospital she was taken to in Glasgow on Tuesday is a brand new "SUPER" hospital opened less than 3 months ago, and it is called "The Death Star" by the locals. It looks futuristic but has been plagued from the start with the usual problems.

http://www.ncbi.nlm.nih.gov/pubmed/?term=Ebola+virus+reactivation

Stimulation of Ebola virus production from persistent infection through activation of the Ras/MAPK pathway
James E. Strong, Gary Wong, [...], and Heinz Feldmann
Back to Top
Hazelpad View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 11 2015 at 10:51am
The only new thing we learned today is from her sister speaking to the press.

She said   Last Monday Pauline reported , ‘I’ve a temperature, my head is splitting and I have a sore neck and photophobia.’ She had also vomited.

On her condition the following was said : The family are receiving ­regular updates but have not had any contact with Pauline. “She is in a tent and is in isolation. She is not well enough to speak to us. She is seriously unwell.

http://www.dailyrecord.co.uk/news/scottish-news/family-condemns-hospital-failures-after-6612236


Ebola can lurk in the CNS so perhaps it has reactivated in this location and. she has viral meningitis. If it is not in the blood but the CSF fluidbit would be a less contagious complication hopefully.

Will keep you updated from Scotland.

Hzx
Back to Top
jacksdad View Drop Down
Executive Admin
Executive Admin
Avatar

Joined: September 08 2007
Location: San Diego
Status: Offline
Points: 47251
Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: October 11 2015 at 6:13pm
I agree - headache, sore neck and photophobia all seem to point to some form of meningitis.
"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 12 2015 at 6:17am
This is one odd situation.   Looking at the Ebola numbers in W. Africa, this is not a common occurrence.  Whoever said this could effect Caucasians differently is probably on to something.   As we've seen with H7N9 only infecting the Asian population, this is yet another example of a similar situation in which a disease has a different impact by race.  Strange situation.
https://www.facebook.com/Avianflutalk
Back to Top
onefluover View Drop Down
Admin Group
Admin Group
Avatar

Joined: April 21 2013
Location: Death Valleyish
Status: Offline
Points: 20151
Post Options Post Options   Thanks (0) Thanks(0)   Quote onefluover Quote  Post ReplyReply Direct Link To This Post Posted: October 12 2015 at 10:36am
Possible but highly unlikely she was reinfected. So she must not have completely cleared. With each cell budding thousands of viridae after the persons initial infection, I would think that in some people the immune response was not complete enough and some cells were alowed to bud only a few resistant filoviridae but enough to keep the virus alive in some isolated part of the body until, perhaps after mutating or masking their make up, they were able to rebound.
"And then there were none."
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 12 2015 at 11:54am

Gets worse.

Update is that 56 close contacts identified, 45 offered vaccination, 25 so far have been vaccinated today, so they must feel the virus is at high enough levels in her fluids she can infect others.

....and this is someone who was released 9 months ago with the experts saying she had completely recovered an was "not infectious in any way".

Didn't we have a previous discussion about how the medical professionals were being overly quick to define the characteristics of this virus. Unfortunately this woman visited a primary school on the day she took ill again.

http://www.bbc.co.uk/news/uk-scotland-34509572


Ebola nurse's close contacts identified and offered vaccination.

A total of 58 people who had been in close contact with Scottish nurse Pauline Cafferkey, who contracted Ebola in Sierra Leone, have been identified.
Ms Cafferkey remains in a serious condition after being readmitted to the Royal Free Hospital in London last week.
She underwent a month of treatment at the same hospital in January.
Health officials said 40 of the 58 people identified had been offered vaccinations.
They were thought to have potentially had contact with Ms Cafferkey's bodily fluids.
Of these, 25 have now been vaccinated, with the remaining 15 either declining to be vaccinated or unable to receive it due to other medical conditions.
'Closely monitored'
The close contacts of Ms Cafferkey were said to be a mixture of healthcare workers, her family, friends and community contacts.
A statement released by the health board said: "All 58 close contacts are being closely monitored. This includes a period of 21 days since their last exposure where they will have their temperature taken twice daily, restrictions placed on travel and, in the case of healthcare workers they have been asked not to have direct patient contact during this period.
"The 25 who were vaccinated will undergo additional monitoring because the vaccine is still being evaluated.
"It is important to stress once again that there is no risk to the general public. Ebola is not spread through ordinary social contact, such as shaking hands or sitting next to someone. Nor is it spread through airborne particles."
The rVSV-ZEBOV vaccine offered to close contacts of Ms Cafferkey is currently being trialled in collaboration with the World Health Organisation and has been tested in more than 7,000 people during the recent outbreak of Ebola virus infection in Guinea.
It is an unlicensed vaccine, which is currently being trialled.
When Ms Cafferkey was released in January she was described as not infectious.
Ms Cafferkey was flown in a military aircraft to the specialist infectious diseases unit at the Royal Free last week.
She had earlier been admitted to the Queen Elizabeth University Hospital in Glasgow after feeling unwell.
Subsequent tests showed that the Ebola virus was still present in her body
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 12 2015 at 12:11pm
Here is the latest statement from NHS Greater Glasgow and Clyde.

Update on Ebola case close contacts

Monday, October 12, 2015

All close contacts of Pauline Cafferkey since she became symptomatic have now been identified.

A total of 58 close contacts have been confirmed and they are a mixture of healthcare workers and Pauline’s friends, family and community contacts.

Decisions on the management of close contacts have been taken by an expert group including, Health Protection Scotland, Public Health England, Scottish Government, NHS Greater Glasgow and Clyde, and other national experts with experience of Ebola.

This group has agreed that, as a precautionary measure, close contacts who have been established as having had direct contact with any bodily fluids would be offered vaccination. These vaccinations have now taken place.      

The rVSV-ZEBOV vaccine offered is currently being trialled in collaboration with the World Health Organisation and has been tested in over 7,000 people during the recent outbreak of Ebola virus infection in Guinea. It is an unlicensed vaccine, currently being trialled.

40 of the 58 close contacts were confirmed as having had direct contact with Pauline’s bodily fluids and were offered the vaccine in line with criteria set out by the expert group:

25 of them accepted the vaccine
15 have either declined the vaccine or were unable to receive it due to existing medical conditions.
It is known from the existing clinical trials of this vaccine that some one in four recipients are expected to experience a rise in body temperature. Therefore, if anyone who has been vaccinated experiences a raised temperature they will undergo a precautionary Ebola blood test. All blood test samples for Ebola in Scotland are tested at the Scottish National Viral Haemorrhagic Fever Test Centre in Edinburgh.

All 58 close contacts are being closely monitored. This includes a period of 21 days since their last exposure where they will have their temperature taken twice daily, restrictions placed on travel and, in the case of healthcare workers they have been asked not to have direct patient contact during this period.

The 25 who were vaccinated will undergo additional monitoring because the vaccine is still being evaluated.

It is important to stress once again that there is no risk to the general public. Ebola is not spread through ordinary social contact, such as shaking hands or sitting next to someone. Nor is it spread through airborne particles
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 7:51am
Update from Scotland today:



A statement released by the hospital on Tuesday said: "We are sad to announce that Pauline Cafferkey's condition has deteriorated and she is now critically ill.
"She is being treated for Ebola in the high level isolation unit at the Royal Free Hospital."



http://www.bbc.co.uk/news/uk-scotland-34529575



This is 9 months after she was cured she is again probably dying from the virus. This doesn't sound like previous cases where you get activation in an eye, this seems like a systemic infection not local. This must be why they have vaccinated all the contacts. Still not very much info yet.


It leaves the question about all the others who recovered. Are they all potential ticking time bombs rather than cured. What happens when Dr Brent gets sick again with some other illness which could lower his immune system and the dormant Ebola become active again. Will he and others become dangerous to those around them ??????   What about those in West Africa? Think of the stigma survivors will get when this story gets out over there. I guess this is why they are being careful as to what they are saying, and hence the scant info we are getting.





Back to Top
Jen147 View Drop Down
Moderator
Moderator
Avatar

Joined: March 23 2013
Status: Offline
Points: 17144
Post Options Post Options   Thanks (0) Thanks(0)   Quote Jen147 Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 11:12am
Wow, that is quite the development!  Never saw it coming myself.  My question would be... where has she been in those 9 months... did she travel back to the area to resume helping like some of the other survivors have said they would (although I don't know if they ever went).
 
If she did go back, could she have been reinfected with a mutated strain?  Probably not likely but just wondering.
Back to Top
Jen147 View Drop Down
Moderator
Moderator
Avatar

Joined: March 23 2013
Status: Offline
Points: 17144
Post Options Post Options   Thanks (0) Thanks(0)   Quote Jen147 Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 11:52am
I'm actually surprised Dr. Brantly or one of the other Americans have not released a statement. 
 
Some names to be on the lookout for:
 
Nina Pham
Amber Joy Vinson
Dr. Craig Spencer
Dr. Kent Brantly
Nancy Writebol
Dr. Rick Sacra
Dr. Ian Crozier
Ashoka Mukpo
 
I can't find the name of the male U.S. clinician that was flown to Maryland.  Was his name ever released?
 
Teresa Romero (Spain)
William Pooley (London)(Donated blood to Pauline Cafferkey)
 
 
I'm sure I missed someone, please post if you know of any others.
 
Back to Top
carbon20 View Drop Down
Moderator
Moderator
Avatar

Joined: April 08 2006
Location: West Australia
Status: Offline
Points: 65816
Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 3:00pm

Ebola nurse Pauline Cafferkey is CRITICALLY ill as her condition deteriorates, the London isolation unit treating her has revealed

  • The Royal Free Hospital in London revealed her condition has deteriorated
  • The nurse, 39, from South Lanarkshire, was admitted to an isolation unit 
  • She was diagnosed with Ebola last December but discharged in January 
  • But last week she felt unwell again and was flown to London for treatment 

By ANTHONY JOSEPH FOR MAILONLINE

PUBLISHED: 23:26 EST, 14 October 2015 UPDATED: 04:13 EST, 15 October 2015

 Pauline Cafferkey who is being treated for a late complication of Ebola is now critically ill.
+7

 Pauline Cafferkey who is being treated for a late complication of Ebola is now 'critically ill'.

Nurse Pauline Cafferkey who is being treated for a late complication of Ebola is now 'critically ill'.

The Royal Free Hospital in London, where she is being treated, this afternoon revealed her condition has deteriorated. 

A statement from the hospital said: 'We are sad to announce that Pauline Cafferkey's condition has deteriorated and she is now critically ill. 

'She is being treated for Ebola in the high level isolation unit at the Royal Free Hospital.'

The nurse, 39, from South Lanarkshire, was admitted to an isolation unit at the Royal Free Hospital in London on Thursday night – four days after being sent home by doctors who diagnosed her with a virus.

Pauline was diagnosed with Ebola in December after returning to Glasgow from Sierra Leone via London.

She was critically ill and spent almost a month in an isolation unit at the Royal Free Hospital before being discharged in late January.

She then started working part time in mid-March as a nurse based in Blantyre Health Centre near Glasgow and had been well when she was last at work on October 1.

Today a leading expert said the return of the virus is 'concerning'. 

 Virologist Professor Andrew Easton, of Warwick University, said that although the virus had persisted in a patient before, it was unusual so long after the first diagnosis.

He said: 'We haven't seen it return after this long. It is concerning. There are lots of unknowns at this stage. It is very difficult to tell and I don't want to predict what the outcome may be.' 

Two weeks ago, Ms Cafferkey received a Pride of Britain award from Lenny Henry and Carol Vorderman in London and met Samantha Cameron in Downing Street the following day.

And on Monday last week she met children at Mossneuk Primary School in East Kilbride, South Lanarkshire, to speak about her charity work in Sierra Leone, where she contracted Ebola.

However, it was just hours after attending the primary school that she fell unwell and visited the out-of-hours GP clinic with Ebola symptoms.

Despite being dismissed, she took herself to the Queen Elizabeth University Hospital in Glasgow on Tuesday night where she was treated in the infectious diseases unit.

Recovered British nurse talks about her ordeal with Ebola
Loaded: 0%
Progress: 0%
00:00
Play
Mute
Current Time0:00
/
Duration Time0:00
Fullscreen
Pauline landed at a nearby RAF base and was taken to the Royal Free in London for care on Thursday night
+7

Pauline landed at a nearby RAF base and was taken to the Royal Free in London for care on Thursday night

The nurse (circled) was diagnosed with Ebola and was seen walking from an ambulance at Glasgow Airport as she was moved by military aircraft to London on December 30 last year. She has now been struck down again
+7

The nurse (circled) was diagnosed with Ebola and was seen walking from an ambulance at Glasgow Airport as she was moved by military aircraft to London on December 30 last year. She has now been struck down again

On Thursday, the NHS nurse was wheeled from a jet at RAF Northolt by medics in hazard suits on a bed surrounded by a protective bubble before being taken to the Royal Free. 

Ebola can occasionally persist for some months in certain tissues as it is retained by parts of the body where the immune system struggles to reach, such as the liquid in the back of the eye.  

Professor Easton said Ms Cafferkey's condition may have worsened as the virus pushed back from where it was contained. 

If this was the case, she would go through the same stages of the virus as she had previously. 

He added that Ms Cafferkey could face experimental drugs, saying that there are 'lots of new treatments that could be used.'

'The usual protocol of testing these drugs is being put to the side because the patient is at such risk. It is up to the highly trained medical staff who understand the risk to decide whether to use them.' 

Health chiefs confirmed that schoolchildren who met with the Ebola-infected nurse the day before she fell ill again were not in danger of catching the killer disease.  

A total of 58 people who have been in close contact with the 39-year-old, who originally contracted Ebola while volunteering in Sierra Leone, are being monitored by health officials.

Of those 25 accepted the unlicensed vaccine, while a further 15 either declined it or were unable to take it due to other medication. 

Ms Cafferkey (circled left) was in Downing Street to meet Samantha Cameron (circled far right) 11 days ago
+7

Ms Cafferkey (circled left) was in Downing Street to meet Samantha Cameron (circled far right) 11 days ago

Nurse Pauline Cafferkey (pictured circled centre) accepted a Pride of Britain award in London less than a fortnight ago from Lenny Henry (far left), Suranne Jones (centre left) and Carol Vorderman and (far right)
+7

Nurse Pauline Cafferkey (pictured circled centre) accepted a Pride of Britain award in London less than a fortnight ago from Lenny Henry (far left), Suranne Jones (centre left) and Carol Vorderman and (far right)

Some of those checked were thought to be healthcare workers and NHS Greater Glasgow and Clyde said around 40 had had direct contact with Pauline's bodily fluids.

It was later revealed that doctors 'missed a big opportunity' to spot she had fallen ill with the potentially fatal virus for the second time.

Her sister,Toni, said the way her sister had been treated was absolutely diabolical.'

She told the Sunday Mail: 'At that point me and my family believe they missed a big opportunity to give the right diagnosis and we feel she was let down. Instead of being taken into hospital, she spent the whole of Tuesday very ill.

'I think it is absolutely diabolical the way she has been treated. We don't know if the delays diagnosing Pauline have had an adverse effect on her health, but we intend to find out. It has not been good enough.

'We think there have been major failings and we just want her to pull through. This kind of recurrence seems to be rare but we don't yet know enough about it.' 

This is the  High Level Isolation Unit at the Royal Free Hospital in London where Pauline Cafferkey is being held
+7

This is the High Level Isolation Unit at the Royal Free Hospital in London where Pauline Cafferkey is being held

NHS Greater Glasgow and Clyde confirmed that Pauline attended the New Victoria Hospital GP out-of-hours service on Monday.

A spokesman said: 'Her management and the clinical decisions taken based on the symptoms she was displaying at the time were entirely appropriate.

'All appropriate infection control procedures were carried out as part of this episode of care.' 

Pauline was admitted to an isolation unit at the Royal Free Hospital in London on Thursday night – four days after being sent home by doctors who diagnosed her with a virus.

Her sister revealed that she had gone to an out-of-hours GP clinic at Victoria Hospital in Glasgow on Monday last week, but the doctor who assessed her diagnosed a virus and sent her home. 

Pauline Cafferkey was taken to Queen Elizabeth University Hospital in Glasgow on Tuesday (pictured). She has since been flown to the Royal Free Hospital in London by RAF where she is being treated in an isolation unit
+7

Pauline Cafferkey was taken to Queen Elizabeth University Hospital in Glasgow on Tuesday (pictured). She has since been flown to the Royal Free Hospital in London by RAF where she is being treated in an isolation unit

Share or comment on this article



Read more: http://www.dailymail.co.uk/news/article-3272304/Ebola-nurse-Pauline-Cafferkey-CRITICALLY-ill.html#ixzz3oa9QdfPs 
Follow us: @MailOnline on Twitter | DailyMail on Facebook
Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖

Marcus Aurelius
Back to Top
Hazelpad View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 4:27pm
No Jen, she has not been abroad since it happened. Initially after recovery she was investigated She has been working back as a nurse in her old job in Blantyre Health Centre which is a very busy place. She still lives on the top floor of a block of flats with other neighbours in Cambuslang. Just going about her normal life, giving talks, and collecting an award or 2. She went to Mossneuk Primary School in East Kilbride the day she took ill.   The first night she presented to medics, she was given an anti sickness injection and sent home.











Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 4:36pm

"Rapid decline of nurse 'cured' of Ebola leaves experts absolutely staggered "


A nurse who recovered after contracting ebola was critically ill last night after an unprecedented relapse that experts described as “staggering”.

Pauline Cafferkey was flown to the Royal Free Hospital, London, in the early hours on Friday after becoming ill in Glasgow. Doctors discovered the virus had managed to survive in her body.

Experts have expressed shock at the severity of her condition.

Jonathan Ball, professor of molecular virology at the University of Nottingham, said the news was “frankly staggering.”

http://www.thetimes.co.uk/tto/health/news/article4586183.ece
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 4:54pm
It must be strange for the survivors and their families now, and an element of what if Ebola is terminal, and not curable.

Will Pooley ( the other British nurse that caught Ebola) is in a bizarre situation. ...he won't be able to comment or make a statement as he now actually works at the hospital in London which treated him and Pauline the first time around, and where she is at present.(Royal Free).


He took a job there a few months ago as he said he felt "emotionally connected" to the Royal Free after his Ebola treatment.

He added: "I bump into nurses in the lift who, a year ago, were saving my life.......wonder how he now feels treating Pauline Cafferty in that very unit, perhaps wondering if her fate will be his eventually.

He must be very confused.

They say because of the small and rare outbreaks of the past there is no or limited long term follow up of survivors.



Back to Top
Hazelpad View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 5:32pm
I noticed also that from the last press statement the Royal Free are now confirming that Nurse Cafferty is suffering from EBOLA, and is being treated for Ebola, and is in a critical condition with Ebola....the words "complications from a previous infection " have now been dropped. This wording is beginning to be picked up now by our local media.

For example:


Prof Evans added: “I think it is interesting that the Royal Free is describing her condition now as Ebola whereas previously it was treating her for symptoms only.

“It is possible that the virus levels have increased, which is extremely serious.


So it is rare but maybe it’s only rare because we haven’t seen outbreaks on the scale.

Read more: http://www.scotsman.com/news/health/ebola-nurse-pauline-cafferkey-fighting-for-life-1-3916710#ixzz3oalY9SGf
Follow us: @TheScotsman on Twitter | TheScotsmanNewspaper on Facebook Read more: http://www.scotsman.com/news/health/ebola-nurse-pauline-cafferkey-fighting-for-life-1-3916710#ixzz3oajUxG2n
Follow us: @TheScotsman on Twitter | TheScotsmanNewspaper on Facebook
Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 8:53pm
wow. Sounds like she's not going to make it.  Chilling.

Just for *****s and giggles, I would sequence it to make sure she isn't patient zero of a mutant strain.  It's a stretch, but this whole thing is off and makes no sense.   Damn near impossible.    They should make sure it's Ebola Zaire and not some crazy mutant making its first appearance.   They thought they would have already beaten it, but treatments are having no effect in a modern hospital.   Let's hope the contacts don't start showing symptoms.  scary stuff.  I would sequence it to be sure.



https://www.facebook.com/Avianflutalk
Back to Top
Guests View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 10:09pm
Dang Albert your very smart thoughts about this are scary!!! I read in one article that her contacts were being followed. How many are there out there and if they go down it will be bad for all of us.
Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 10:27pm
Ya I don't really like this one.  I'm assuming they're treating her the exact same way they did the first time, but this time it's not working.   Reminds me of the Borg.  It's now adapted to the treatment and ravaging her.  This second version has beaten the original remedies, which would indicate it's changed a little.  With this one, resistance is futile, at the moment.    

Interesting to note that they already vaccinated some of the contacts for Ebola.  The vaccination probably wouldn't work if they're already infected, but they tried it.  Wondering if they're not thinking this one could be different as well. 

 
https://www.facebook.com/Avianflutalk
Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 14 2015 at 10:35pm
This was somewhat my thought.  Maybe something such as Zmapp is responsible, or could even cause a mutation.



Scottish Nurse Who Had Ebola Is Back in Hospital and Critically Ill


The case adds yet another terrifying layer to the Ebola outbreak: A Scottish nurse who recovered from Ebola 10 months ago has been rehospitalized and is now critically ill, the Royal Free Hospital in London reported Wednesday.

Scientists have long known that the Ebola virus can persist for months in certain tissues of the body that are relatively protected from the immune system, including the eyes and the testes.

A report published Wednesday in The New England Journal of Medicine, for instance, found traces of Ebola in some men’s semen up to nine months after they fell ill. Another report in the same journal presented additional evidence that an Ebola survivor in Liberia had transmitted the disease to a sexual partner roughly six months after having developed symptoms.

Yet the case of the nurse, Pauline Cafferkey, points to how much is still unknown about the virus and its long-term effects.

Doctors are grappling with why Ms. Cafferkey’s current illness happened so many months after her initial infection in Sierra Leone, where she had gone as a volunteer, and why similar cases have not been well documented in the three West African countries that are now home to thousands of survivors.

Photo
Pauline Cafferkey had seemed to recover from Ebola. Credit Lisa Ferguson/Scotland on Sunday, via Press Association, via Associated Press

“It’s an emerging story, emerging science,” said Dr. Daniel Bausch, a technical consultant on Ebola with the World Health Organization.

Speculation has focused on the potential role of Ms. Cafferkey’s severe initial illness, and even on the experimental treatments she and the few other patients treated in Western hospitals received.

At the same time, the case adds to concerns about the ramifications of the continuing outbreak in West Africa. Two new cases in the past two days in Guinea have dashed hopes that the outbreak, which has killed more than 11,000 people, was finally ending.

“It’s reminded people that the consequences go on so much longer for survivors,” said Dr. Bruce Aylward, who heads the World Health Organization’s Ebola effort. “It’s really spurred concern we make sure the needs of these people aren’t lost.”

The Royal Free Hospital, which last Friday referred to Ms. Cafferkey’s illness in a news release as “an unusual late complication of her previous infection,” said Wednesday that she was being treated for Ebola. The virus, several experts said, managed to somehow persist and apparently re-emerged to cause a severe disorder of her central nervous system. Dr. Aylward said her spinal fluid had tested positive for traces of Ebola.

“This isn’t a recurrence of Ebola hemorrhagic fever; this is clearly a meningitis-like syndrome, a neurological syndrome, which is a result of the lingering of Ebola virus,” said Stuart T. Nichol, chief of the viral special pathogens branch at the Centers for Disease Control and Prevention in Atlanta. He stressed that the complication appeared to be extremely rare.

“We’d think the likelihood of these types of events is probably higher with cases where patients are very severely, critically ill,” Dr. Nichol said. He theorized that very high concentrations of virus in the blood could seed areas of the body that are harder for the immune system to reach.

Ms. Cafferkey had seemed healthy until very recently and went to a clinic at a hospital after complaining of feeling sick, according to British media reports. The clinic sent her home, the reports said.

Clinicians following patients in West Africa have documented a range of more common complications in survivors. “Body aches, joint pains, eye problems, and ear problems,” said Audrey Rangel, field coordinator for the International Medical Corps in Kambia, Sierra Leone, which helps run a clinic for Ebola survivors.

Photo
Ms. Cafferkey in Africa. Credit Cafferkey Family / Handout/European Pressphoto Agency

Col. Foday Sahr, commanding officer of the joint medical unit in Sierra Leone, said that of 290 registered Ebola survivors being followed weekly at a military hospital in Freetown, one or two exhibited neurological symptoms including weakness on one side of the body, but that no delayed cases of encephalitis or meningitis had been documented.

Still, it is possible that doctors have not found more of these cases in the past because they have not been looking for them. “That’s not how we thought the disease worked,” Dr. Bausch said.

Dennis Khakie, 42, died suddenly in September nearly a year after having recovered from Ebola at a treatment unit run by the International Medical Corps in Liberia. “He just started convulsing,” said Sam Siakor, Mr. Khakie’s nephew and a former nurse aide at the unit.

While stories of patients like this occasionally emerge, Dr. Bausch said, “trying to figure out what they died of and whether it’s really related to Ebola is difficult.”

A child who had recovered from Ebola and was discharged from a Doctors Without Borders treatment center in Liberia last year soon developed a fever, “tested positive again, and had an encephalopathy,” a brain disorder, said Dr. Armand Sprecher, an Ebola expert with the charity.

Perhaps the most relevant case is that of Dr. Ian Crozier, who contracted Ebola in Sierra Leone and, less than two months after recovering, developed a severe inflammatory condition deep inside his left eye, which was harboring the Ebola virus.

While virus was not found in Dr. Crozier’s blood or cerebrospinal fluid, a scan of his brain indicated that he had suffered from encephalitis, Dr. Bausch said. In West Africa, patients as ill as Dr. Crozier or Ms. Cafferkey might not have survived “to experience these later manifestations,” he surmised.

One possibility is that late complications could be an unanticipated consequence of experimental treatments that include antibodies, like ZMapp, that help remove the virus from the patient’s blood, but are not thought to be capable of crossing from the bloodstream into the brain.

By decreasing the amount of virus in the blood, “you perhaps blunt the immune system,” Dr. Bausch said. “It’s all speculation, but it’s scientifically sound speculation.”

When patients with a different hemorrhagic fever caused by the Junin virus were treated with blood plasma containing antibodies from survivors, around 10 percent of them later developed neurological complications that were in rare cases severe, researchers reported in the 1970s. In a study of antibody treatments for Rift Valley Fever, some patients also developed brain disease, Dr. Nichol said. However the timeline was within days or weeks of the initial infection, not months.

While Ms. Cafferkey’s contacts are being monitored in Britain, experts said that the type of illness she developed was unlikely to pose a threat to others. “The huge concern everyone has is that this does not result in a new wave of stigmatization of survivors, because of course it’s a very, very different risk, a personal risk,” Dr. Aylward said.

https://www.facebook.com/Avianflutalk
Back to Top
Hazelpad View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 15 2015 at 2:25am
Very good point Albert about sequencing. The results of that will add a huge bit to the puzzle. If it has mutated I wonder how much of the present vaccine will fit. Either that or perhaps the virus works like HIV and quietly destroys the immune system in one way or another.

Something else about this outbreak is that some of those people flown home would never have survived without organ support, oxygen support, antibodies, antivirals, and teams of 20 plus doctors.    I remember Pauline Cafferty got real sick at the time, like hours from death and u -turned. Perhaps the treatment only got her over a " bout of Ebola"....if she survives again, what next for her. How do you have a life knowing you could be a walking biohazard.

Hzx







Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 15 2015 at 6:11am
I of course wish should she would survive this, but I'm not sure it's possible once you hit the "critical' phase with this. 6 - 7 days in the hospital and now in critical?  Seems like they may have missed the threshold to turn it around.   Sad news for her and her family. 

As we know, the first group who will possibly show symptoms next are the nurses at Queen Elizabeth Hospital who treated her before they knew what they were dealing with.  A very high probability with that and it should be expected at anytime.

Wouldn't that be some scary stuff when they develop symptoms and they're unable to treat it.   Can't remember seeing if they're in isolation, but they better be.  
https://www.facebook.com/Avianflutalk
Back to Top
carbon20 View Drop Down
Moderator
Moderator
Avatar

Joined: April 08 2006
Location: West Australia
Status: Offline
Points: 65816
Post Options Post Options   Thanks (0) Thanks(0)   Quote carbon20 Quote  Post ReplyReply Direct Link To This Post Posted: October 15 2015 at 3:01pm
no one has pointed out the the real scary part of this story'

what happens if all the other people in Africa are still infected and  infectious 

this could be very very bad ,

i hope they are being monitored ,and even if they are what can we do ........

seems like 

NOTHING...............

OH DEAR..............


Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖

Marcus Aurelius
Back to Top
DeepThinker View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: September 26 2015
Location: So. California
Status: Offline
Points: 3245
Post Options Post Options   Thanks (0) Thanks(0)   Quote DeepThinker Quote  Post ReplyReply Direct Link To This Post Posted: October 15 2015 at 3:10pm
This is scary...   If ebola ever becomes widespread it could have a devastating effect on our society and culture.

We would be forced to divide our self's into two classes of humans.  One group that has been exposed to ebola and one group that hasn't.   Those two groups would be allowed very little contact with each other.
Back to Top
DeepThinker View Drop Down
V.I.P. Member
V.I.P. Member
Avatar

Joined: September 26 2015
Location: So. California
Status: Offline
Points: 3245
Post Options Post Options   Thanks (0) Thanks(0)   Quote DeepThinker Quote  Post ReplyReply Direct Link To This Post Posted: October 15 2015 at 3:14pm
Albert... even if they have already been exposed the vaccine might still be useful.   From the way I understand it... the virus isn't particularly violent in its effects on the body.   What makes Ebola so devastating is that it can hide from your immune system till it is too late.  Maybe the vaccine will bring about a quicker immune reaction and a better outcome.
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 15 2015 at 5:11pm
Perhaps the previous use of Zmap antibodies, or plasma donated from other survivors, mopped up the virus before her immune system got a chance to mount a good response. Yes she got better by the artificial removal of the virus from her blood, but her body may have no immunological memory of it. So later when virus gets reactivated in hidden central nervous system, and when it starts to spill out again into her blood, there is no immune response primed, ready and waiting to tackle it.

In contrast those who beat Ebola naturally do so because they have processed the virus, and are capable of making their own circulating antibodies. If virus reappears out a hidden location, the immune system has the tools to cope rapidly with it, and the infection is controlled before the patient has any idea he evet had a recurrence.

So those who recover from Ebola naturally may do better in the long term that those who recover with artificially transfered antibodies.....all survivors are equal though some may be more equal than others.

Albert is right the sequencing is important, As is the locations of positive samples, is it just spinal fluid, or is it also blood, saliva, faeces etc ? The fact they offered 40/59 contacts experimental vaccines ; uptake of 26 now), these numbers seem to be suggesting more than just her spinal tap sample being positive. Sounds like vomit, blood, faeces, as if only spinal fluid why so many people on follow up.

This is all theory and guess work as so little is being said.

Hazelpad
Back to Top
ViQueen24 View Drop Down
Adviser Group
Adviser Group
Avatar

Joined: May 14 2013
Location: Verona, PA
Status: Offline
Points: 12270
Post Options Post Options   Thanks (0) Thanks(0)   Quote ViQueen24 Quote  Post ReplyReply Direct Link To This Post Posted: October 16 2015 at 12:31am
It's important to remember how sometimes a virus can come back years later to bite in the butt. Spanish Influenza>encephalitis lethargica; chickenpox> shingles; polio> post-polio syndrome.
Back to Top
Medclinician View Drop Down
V.I.P. Member
V.I.P. Member
Avatar
Valued Member Since 2006

Joined: July 08 2009
Status: Offline
Points: 23322
Post Options Post Options   Thanks (0) Thanks(0)   Quote Medclinician Quote  Post ReplyReply Direct Link To This Post Posted: October 16 2015 at 12:31pm
Originally posted by carbon20 carbon20 wrote:

no one has pointed out the the real scary part of this story'

what happens if all the other people in Africa are still infected and  infectious 

this could be very very bad ,

i hope they are being monitored ,and even if they are what can we do ........

seems like 

NOTHING...............

OH DEAR..............




I have posted this several times.   Med
"not if but when" the original Medclinician
Back to Top
Medclinician View Drop Down
V.I.P. Member
V.I.P. Member
Avatar
Valued Member Since 2006

Joined: July 08 2009
Status: Offline
Points: 23322
Post Options Post Options   Thanks (0) Thanks(0)   Quote Medclinician Quote  Post ReplyReply Direct Link To This Post Posted: October 16 2015 at 12:32pm
http://m.gbcghana.com/1.7804777

Posted Oct 16, 2015 at 10:03am
A nurse who contracted Ebola while working in West Africa is now "critically ill" with complications arising from the infection.

Ms Cafferkey, 39, contracted Ebola while working at a treatment centre in Sierra Leone last year.

She spent almost a month in isolation at the Royal Free at the beginning of the year after the virus was detected when she arrived back in the UK.

She was later discharged after apparently making a full recovery, but it was discovered last week that Ebola was still present in her body.
"not if but when" the original Medclinician
Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 16 2015 at 6:36pm
Its still not making a lot of sense.  There would be an explosion of cases in W. Africa right now.  

There is one distinct difference between this case and the cases in Africa.  She was treated with Zmapp.   And if that's the case, they should again sequence this Ebola to ensure zmapp isn't creating or triggering a mutation.  Big pharma may hype that it persists for 9 months and imply that it's common, but the fact still remains that her case is different from those in W. Africa due to her treatment using zmapp.  Same old story ... follow the money.  
https://www.facebook.com/Avianflutalk
Back to Top
onefluover View Drop Down
Admin Group
Admin Group
Avatar

Joined: April 21 2013
Location: Death Valleyish
Status: Offline
Points: 20151
Post Options Post Options   Thanks (0) Thanks(0)   Quote onefluover Quote  Post ReplyReply Direct Link To This Post Posted: October 16 2015 at 7:00pm
Yeah, I agree and Hazel nailed it I think.
"And then there were none."
Back to Top
Technophobe View Drop Down
Assistant Admin
Assistant Admin
Avatar

Joined: January 16 2014
Location: Scotland
Status: Offline
Points: 88450
Post Options Post Options   Thanks (0) Thanks(0)   Quote Technophobe Quote  Post ReplyReply Direct Link To This Post Posted: October 17 2015 at 11:51am
Oh s*** now I am your yessman Oneflu'.  I agree: Hazlepad nailed it.
How do you tell if a politician is lying?
His lips or pen are moving.
Back to Top
CRS, DrPH View Drop Down
Expert Level Adviser
Expert Level Adviser


Joined: January 20 2014
Location: Arizona
Status: Offline
Points: 26660
Post Options Post Options   Thanks (0) Thanks(0)   Quote CRS, DrPH Quote  Post ReplyReply Direct Link To This Post Posted: October 17 2015 at 9:54pm
Originally posted by Albert Albert wrote:

Its still not making a lot of sense.  There would be an explosion of cases in W. Africa right now.  


I'm not convinced that there isn't.  This is good:


Considering all of the negative PR brought down on the governments of afflicted countries, superstitions and hostility to outsiders, I'm sure we have a "slow simmer" of cases going on all across West Africa.  





 


CRS, DrPH
Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 18 2015 at 7:48am
It's been well over a year since Ebola exploded in W.  Africa.   There should be hundreds of new cases each week right now, especially given the sexual habits of those folks.  We would probably see a surge in cases, and also realizing that it will now be impossible to "ever" eradicate it.   We would also probably see a surge in the overall death rate, given the severity of this case. 

I believe the manufactures of Zmapp probably signed a waiver of liability and a non-disclosure, saying look, it's not yet proven and we don't want to be responsible in the end for whatever happens.   Or they all already knew and it had been tested on previous outbreaks.   If it could also trigger a potential mutation resulting in a global disaster, they would also keep a lid on it.  They didn't give her a blood transfusion (or hardly anyone in the past),  probably because those survivors also used zmapp, and there may be a low (or unknown) risk of a mutation occurring.   Whatever the case, ultimately it points back to zmapp at the moment.  

Also makes me wonder, back in the day, they said they only had a handful of zmapp available., which always struck me as odd.  Who only creates 30 or so?   If that was a lie, it wouldn't be because it might later prove to be ineffective and because Ebola may relapse down the road, but because they feared a mutation could take place.   I'm pretty sure they have sequenced this strain by now as standard protocol. 
 
https://www.facebook.com/Avianflutalk
Back to Top
Jen147 View Drop Down
Moderator
Moderator
Avatar

Joined: March 23 2013
Status: Offline
Points: 17144
Post Options Post Options   Thanks (0) Thanks(0)   Quote Jen147 Quote  Post ReplyReply Direct Link To This Post Posted: October 18 2015 at 11:20am
There are conflicting reports that she received blood plasma from William Pooley.  Reports that I read varied from yes he did, to he was expected to, to hasn't been confirmed yet.  But no reports that flat out deny it.
Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 18 2015 at 11:55am
Wonder if they treated her with zmapp again. If not, why not?    Could have saved her perhaps, so why not?
https://www.facebook.com/Avianflutalk
Back to Top
Hazelpad View Drop Down
Adviser Group
Adviser Group


Joined: September 09 2014
Status: Offline
Points: 6910
Post Options Post Options   Thanks (0) Thanks(0)   Quote Hazelpad Quote  Post ReplyReply Direct Link To This Post Posted: October 19 2015 at 10:54am

https://www.royalfree.nhs.uk/news-media/news/

Update from Royal Free Hospital website.


Update on Pauline Cafferkey
19 October 2015

Updated: 3pm We are able to announce that Pauline Cafferkey’s condition has improved to serious but stable.


Note they are still saying next to nothing,






Back to Top
Albert View Drop Down
Admin
Admin


Joined: April 24 2006
Status: Offline
Points: 47746
Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: October 19 2015 at 1:56pm
That's great news and great work done on her.  Taking her from critical to serious sounds a lot better.  Every time I see that pic with a big smile can't help but hope for the best.
https://www.facebook.com/Avianflutalk
Back to Top
Medclinician View Drop Down
V.I.P. Member
V.I.P. Member
Avatar
Valued Member Since 2006

Joined: July 08 2009
Status: Offline
Points: 23322
Post Options Post Options   Thanks (0) Thanks(0)   Quote Medclinician Quote  Post ReplyReply Direct Link To This Post Posted: October 21 2015 at 9:21pm
http://www.express.co.uk/news/uk/613667/Ebola-nurse-Pauline-Cafferkey-significant-improvement-ebola-virus

EBOLA nurse Pauline Cafferkey has "made a significant improvement" after battling against the potentially fatal virus for the second time.


"not if but when" the original Medclinician
Back to Top
 Post Reply Post Reply Page  12>
  Share Topic   

Forum Jump Forum Permissions View Drop Down