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Now At Level 6 |
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Medclinician 
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Member Since December, 2005 Joined: July 08 2009 Status: Offline Points: 2017 |
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 Posted: August 16 2009 at 10:50am |
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no- not a thread called level 6- remember 4836 of my posts were deleted along with a hundred threads. On the day of the announcement of the Pandemic June 11, 2009 I posted thread with the announcement - a video of Dr. Chan- and even an entry point link during the announcement for users to log in through my link to the meeting. Also a second thread was posted same day of a prior announcement two hours before the noon meeting where I logged in via phone conference. Since both Mary and I were delete and many threads are now labeled guest because we lost them all- it is hard to know who started what. Albert had promised to restore all of my 4000+ posts which never happened. Almost a years worth of work. So- Mary and I have been posting on this - for a long time. .. I think Mary actually had more posts than 4800 deleted and had to start as a new user. On other locations on the net I posted the same day, same article- We have moved into a new phase of the Pandemic which is beyond Level 6- actually this would be a grade 2 level seriousness or 3 and we are seeing that in some areas. Much appreciate Mary's work when we were co-administrators on this site- before things changed. Now we have two-three more Pandemics coming which will probably be worse than Swine Flu. And as this site originally was on Avian and moved to Swine- it will probably shift to Henta and Nipah- which I posted on. We interestingly enough, if you will read the discussion thread have the Dengue Problem in Brazil as well as many active cases of a new form of Swine Flu coming from Brazil. Had posted the outbreak in Yucatan, but then we had a person working with the government posting on my thread that he was on his way to the site and changing his location to Mexico. Have tracked two patient zeros on this and currently, the reason I cannot post as much is we are in the field tracking the real numbers and outbreaks which are totally different from what is being formally released. Just the facts. I was cyber at the conference when this announced and on line with the pre announcement. In 30 days if this one does not pick up steam it will be dropped as threat altogether after a trillion dollars is made on the vaccine and no one will care. Meantime we have active mutations and outbreaks all over the place- and almost no country by county coverage of the outbreaks. So much material was lost - it is hard to know who has done what. And every time I post a new bad outbreak.. there is an instant post that it is not a problem. When you stop counting and stop reporting (New York) that does not mean you have less cases or a problem.. it means they aren't counting. And if you have "friends in the clinics who are seeing cases" that means nothing. The triage nurses are telling people to stay home and not to come to ER. Of course they are going be be less. a tired Medclinician Medclinician |
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Mary008
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Posted: August 16 2009 at 3:22pm |
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AP ENTERPRISE: Schools gear up for swine flu shots
 .................................................................................................
By LIBBY QUAID and LAURAN NEERGAARD Associated Press - Sun Aug 16, 2:12 pm ET WASHINGTON - Hundreds of schools are heeding the government's call to set up flu-shot clinics this fall, preparing for what could be the most widespread school vaccinations since the days of polio.
source fDVORfQG5581Fk8fVJRIF;_ylu=X3oDMTJsam5xMTFhBGFzc2V0A2FwLzIwMDkwODE2L3VzX3
N3aW5lX2ZsdV9zY2hvb2xzBGNwb3MDMgRwb3MDNwRzZWMDeW5fdG9wX3N0b3J5BHNsaw
NhcGVudGVycHJpc2U-
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Now At Level 6 Thread by Mary008 |
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happiness is
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Posted: August 16 2009 at 6:56pm |
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Mary the reference was to why we have to get more than one vaccination for a disease
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dreamer
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Mary008
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Posted: August 17 2009 at 8:41am |
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good topic, worth repeating.
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Mary008
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Posted: August 22 2009 at 3:31pm |
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More thoughts on waves...
The graphs the CDC puts out.. show in a given state the begining and ending of
serious illness (very ill tested for H1N1 and or Hospitalized)
within that state... and the number of weeks it takes to come to an end
of that serious illness.... Usually driven by statistics from a large city in that state.
When that serious ilness ends...even if a lot of people all over the state are still becoming
ill...they are mildly ill getting over it at home and not showing on a graph, ....meaning, after
a point.... it is highly infective but not extremely virulent.
So technically there are waves of
serious illness within each state that the CDC uses to draw a "state graph of serious
illness."
And the graphs for all states are interestingly different.
When the serious illness count goes way down... as it did in many states this summer
there is no need to keep (serious illness) graphs. End of counts.
................
New York Graph
..................................
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Mary008
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Posted: August 24 2009 at 10:57am |
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Universities Are Preparing for Back-to-the-Classroom Outbreaks of Swine Flu
...............................................................................................................................
By DONALD G. McNEIL Jr. Published: August 22, 2009 Excerpt-
"We have to-go packs with soup, Tylenol and Gatorade," said Dr. Mary Covington, director of student health at the University of North Carolina, Chapel Hill, "and we could do boxes with meals-ready-to-eat that could be put in a microwave." By following guidelines on www.flu.gov, most universities hope to avoid shutting down.
The first priority will be, as one administrator put it, "to thin out the herd." Sick students will be encouraged to go home, visit other relatives, even impose on kindly family friends.
Because most dormitories are full, some universities will offer healthy students cots so they can sleep elsewhere while their roommates recover.
Mary008
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Mary008
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Posted: August 24 2009 at 3:20pm |
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Perhaps the Schools should pass out Vit/hormone D3?
....................................................................................................... Very difficult to find info on the Universal Shot...
perhaps that is not so popular to Big Pharma?
The Patent Seekers are talking Designer Drugs :?
Influenza A NS1 Protein -
An Attractive Target for Antiviral Drug Design
......................................................................................... Ns1 protein inhibitors Patents
............................................................
The influenza NS1 protein inhibits the innate immune response of an infected cell and is required for a pathogenic influenza infection. The present inventors developed an assay for NS1 protein function and screened a library of organopharmaceuticals to identify compounds that blocked NS1 protein function. Active compounds from the first assay were screened in a second assay for virus growth and those that inhibited virus growth were selected for further study.
Since NS1 protein is highly conserved across major influenza subtypes and is not a major antigen for generating anti-influenza response,
there is no positive selective pressure for natural variants of NS1 protein.
This suggests that drugs that target NS1 protein will be broadly effective against influenza subtypes.
Indeed, by attenuating (OMG) the virual infection, the NS1 protein inhibitors described herein may prevent disease while simultaneously allowing an
immune response to the infecting strain, thereby giving lasting protection to that
particular strain of virus.
New strains of influenza caused by antigenic drift appear at regular frequency, usually annually, and begin a cycle of infection which typically travels around the globe. Approximately every year, at least one minor change occurs in either the hemagglutinin or neuraminidase antigens (or both), but that change is sufficient to render those persons who had a previous strain susceptible to the new strain. As influenza is caused by a variety of species and strains of viruses, in any given year some strains can die out while others create epidemics while yet another strain can cause a pandemic. Little is known about how individual epidemics are initiated.
So Folks... we may want to take our Vit. D3 ... which is not new information...see PubMed
......................................................................................................................................
The term vitamin D is, unfortunately, an imprecise term referring to one or more members of a group of steroid molecules.
Vitamin D3, also known as cholecalciferol (I take this, 2 tiny drops)
is generated in the skin of animals when light energy is absorbed by a precursor molecule 7-dehydrocholesterol.
Vitamin D is thus not a true vitamin, because individuals with adequate
exposure to sunlight do not require dietary supplementation.
There are also dietary sources of vitamin D, including egg yolk, fish oil and a
number of plants. The plant form of vitamin D is called vitamin D2 or ergosterol.
However, natural diets typically do not contain adequate quantities of vitamin D,
and exposure to sunlight or consumption of foodstuffs purposefully
supplemented with vitamin D are necessary to prevent deficiencies.
From PubMed
.................... 1: Pathol Biol (Paris). 1994 Feb;42(2):163-72.Links
[Vitamin D and the immune system][Article in French]
Thomasset M. Inserm U 120, Alliée CNRS, Hôpital Robert Debré, Paris, France. .......................................................................................................................... Excerpts-
There is now increasing evidence that the hormonal form of vitamin D, 1,25(OH)2D3, is
involved in the regulation of the immune system. ...Local production of the hormone in various infectious diseases can benefit the immune environment.
...The hormone inhibits lymphocyte proliferation and immunoglobulin production in a dose-dependent fashion. It also blocks the accumulation of the mRNAs for IL-2, IFN-gamma and GM-CSF. It interferes with T helper cell (Th) function, reducing Th-induction of immunoglobulin production by B-cells and inhibits the passive transfer of cellular immunity by Th in vivo. The steroid hormone promotes suppressor cell activity and inhibits the generation of cytotoxic and NK cells. Source-
......................................
Mary008
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Mary008
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Posted: August 24 2009 at 5:40pm |
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.
We are seeing some Drug names we don't recognize? Or is it just me :) anyway... one is German and one is from the UK...but we have similar under diff. names.
here they are. You can ask your Doc about them... before you need them.
From Wikipedia, the free encyclopedia
Tramadol ...............
Prescription Only (S4)(AU) POM(UK) Routes oral, IV, IM, rectal, sublingual, buccal Tramadol (Tramal, Ultram, Mabron, Ralivia, Ryzolt, Tradonal, Tramacet, Tridural, Ultracet, Zamadol, Zydol, Zytram) is a centrally acting analgesic, used for treating moderate to severe pain. It is often categorized as an opioid, although it is chemically not related to the opioid
class of drugs. It does, however, appear to have agonist actions at the μ-opioid receptor as well as the noradrenergic and serotonergic systems.[1][2][3] Tramadol was developed by the German pharmaceutical company Grünenthal GmbH in
the late 1970s.[4][5] Tramadol's chemical structure is quite different from those of opioids. The closest chemical relative of tramadol in clinical use is tapentadol, which is a member of the same chemical class as tramadol and also developed by Grünethal. It is marketed in the US by Johnson & Johnson Pharmaceutical Research and Development under the brand name Nucynta.[6]
Tapentadol is a Schedule II controlled substance in the US, whereas tramadol is not a controlled substance in the US and is available with a regular prescription.
........................................... and...
In The UK... Swine Flu: Paracetamol, plenty of fluids & rest 13 Aug 2009, 0434 hrs IST, Sudeshna Sen, ET Bureau ..........................................................................................................
Paracetamol ...................... or acetaminophen... is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer).
It is commonly used for the relief of fever, headaches, and other minor aches and pains, and is a major ingredient in numerous cold and flu remedies. In combination with non-steroidal anti-inflammatory drugs (NSAIDs) and opioid analgesics, paracetamol is used also in the management of more severe pain (such as cancer or postoperative pain).[1] While generally safe for human use at recommended doses, acute overdoses (above
1000 mg per single dose and above 4000 mg per day for adults, above 2000 mg per day if drinking alcohol[2]) of paracetamol can cause potentially fatal liver damage and, in rare individuals, a normal dose can do the same; the risk is heightened by alcohol consumption. Paracetamol toxicity is the foremost cause of acute liver failure in the
Western world, and accounts for most drug overdoses in the United States, the United Kingdom, Australia and New Zealand.[3][4][5][6] Paracetamol is derived from coal tar, and is part of the class of drugs known as “aniline analgesics”; it is the only such drug still in use today.[7]
It is the active metabolite of phenacetin, once popular as an analgesic and antipyretic in its own right, but unlike phenacetin and its combinations, paracetamol is not considered to be carcinogenic at therapeutic doses.[8]
The words acetaminophen and paracetamol both come from chemical names for the compound: para-acetylaminophenol and para-acetylaminophenol. In some contexts, it is simply abbreviated as APAP, for N-acetyl-para-aminophenol. http://en.wikipedia.org/wiki/Paracetamol
..................................... and my Doc gave me antihistimine and codine for a bad flu in winter 98/99
syrup twice a day, for a week... and I slept a lot...wonderful.
...................... Mary008
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Mary008
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Posted: August 24 2009 at 5:52pm |
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and another Drug...
Peramivir ................. Peramivir is an experimental antiviral drug being developed by BioCryst
Pharmaceuticals for the treatment of influenza .
Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of
influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. The development of peramivir is supported by the US Department of Health and Human Services as part of the US government's effort to prepare against the threat of an
i
nfluenza pandemic.[1]
(I wonder if this was why Warren B. Bought so much J&J?) The drug has had a long history. An oral formulation was abandoned by Johnson and Johnson due to poor bioavailability.[2] BioCryst is now developing a injectable version, in partnership with Green Cross Pharmaceuticals in South Korea and with Shionogi Pharmaceuticals in Japan. The drug is in Phase II studies.[3][4] and.... White House Panel Says Speed up Flu Drugs, Vaccines
By Maggie Fox, Health and Science Editor August 24, 2009 excerpt-
Calling the H1N1 pandemic "a serious threat to our nation", they also urged the U.S. Food
and Drug Administration to quickly decide on new, intravenous formulations of flu drugs,
including current drugs such as Roche AG's Tamiflu and GlaxoSmithKline's Relenza but also
BioCryst Pharmaceuticals' experimental drug peramivir.
.................................................
Mary008
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Mary008
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Posted: August 25 2009 at 11:11am |
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http://knol.google.com
Some companies have reported a low production yield of only 30% with Swine Flu batches/lots in comparison with seasonal influenza vaccines. MedImmune (Astra Zeneca) new nasal spray pandemic vaccine uses a different strain (live, attenuated) which grows much faster than the inactivated virus.
Rich nations have locked in and ordered most of the current capacity for antivirals and pandemic flu vaccines. France and UK have ordered supplies to cover entire population while Germany for 30% and USA for over 40% of its population in the first phase and 80% in the second phase if required.
Leading vaccine companies have started or plan to start clinical testing of the Swine Flu Vaccines in healthy volunteers. Clinical trials have started in Australia and Europe. The USA government announced plans to test Sanofi Aventis and CSL vaccines in 2400 healthy subjects at 8 medical and university hospitals. These hospitals are involved in testing of seasonal flu vaccine. Other companies Novartis, Glaxo, Merck, Baxter have their own clinical testing programmes to obtain FDA and EMEA approval.
Adverse reactions to seasonal flu vaccine include aches, fever and sore arms. Allergy to egg proteins used for vaccine cultures in some patients leads to rare cases of hives, dizziness and breathing problems. The most serious Guillain-Barrè syndrome, for unknown reasons, is reported in 1 out of 100,000 patients receiving vaccine. It leads to serious nerve damage and muscle weakness.
Have a serious underlying illness. All patients with chronic lung, heart, kidney, neurological conditions, diabetes, immunosuppressive treatment, pregnant women, elderly >65 yrs, babies <5 yrs
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Mary008
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Posted: August 25 2009 at 12:45pm |
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Page 7
{So what are your thoughts about vaccinated humans? After reading this?)
Can legitimately be used in a targeted manner to support containment -eg ring vaccination around disease hotspots where (HUMAN) density is high?}
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The vaccinated animal is the dangerous one, because it looks healthy but may shed Excerpt from-
The Equine Influenza Epidemic August 2007 - March 2008
source http://www.pandemic.net.au/files/Pandemic_Forum_Presentations/Equine_Influenza_Lessons_Learnt.pdf |
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Mary008
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Posted: August 25 2009 at 11:16pm |
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Someone was afraid of vomiting and it is one of the lesser symptoms... as well as
Fever 93% Cough 83% Shortness of Breath 54% Fatigue / weakness 40% Chills 37% Muscle pain/aches 36% Runny /stuffed Nose 36% Sore Throat 31% Headache 31% Vomiting 29% Wheezing 24% Diarrhea 24% ................................................................I Got Fishermans Friend Cough Drops... They were wonderful...made me cough and the
mucus sitting in there was a goner as I coughed (it hurt a bit) and then I felt so much
better. I think I'l buy a dozen for family.
Note On Fever
........................
The New York Times
.......................................... By LAWRENCE K. ALTMAN, M.D. Published: August 10, 2009 The Doctor's World
Seeking Lessons in Swine Flu Fight In full...well worth reading here- ...The standard definition of influenza includes a fever. But an odd feature of the new
virus is the lack of fever in a significant proportion of documented cases, even after
some patients become seriously ill.
......................
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Mary008
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Posted: August 26 2009 at 11:50am |
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.
Please note... CDC (COCA)
source
Do not get a seasonal (LIAV) Live- Attenuated Flu vaccine (like FluMist )
and a pandemic H1N1 2009 vaccine... at the same time. (a no no )
......................................................................................................................
The Priority Groups must receive a
second vaccination...21 days from the 1st vaccination
This Priority Group must have the second vaccine ....Before....
other groups receive their first vaccination.
.....................................................................
Then... healthy people age 25 through 64 will be able to receive vaccine.
Followed by persons 65 and older.
.................................................................
When I posted target groups... I was under the impression that people over 65
Should be targeted. But the (COCA Call) latest is ...that they are not seeing elderly
in long term care ...becoming ill in large numbers.
(my understanding of what I read)
A H1N1 2009 Monovalent Vaccine (Pandemic Swine Flu Vaccine)
These are the current - Target Groups - as of August 26, 2009
..............................................................................................................
Approx 159 million people.
Pregnant Women
Children Under 6 mo. and the people they... live with or.... who care for them.
Health Care and Emergency Medical Personnel
All People ... 6 months through 24 years of age
All People .... 25 through age 64 yrs with Medical Conditions/and Obesity
......................................
after the target groups receive their ...second vaccine....
Vaccine may be used for the following-
All people... age 25 through 64 yrs
Followed by
All poeple age 65 and older
.......................................................................
If you have an Inactivated (Not Live) ... seasonal flu vaccine ...
You may also... at the same time (must be in a different area/ arm/leg/fanny)
have a Pandemic Swine Flu shot.
(may not be ok for young children, pregnant women or babies, ASK)
Please ask about single dose vaccine for pregnant women and young children/babies
.............................................................................................................................................
ASK... For
Unadjuvated or non adjuvanted Single Dose A H1N1 2009 Monovalent Vaccine
(All Multi dose contain adjuvant)
............................................................................................................................................
PRINT this out.... put it in your purse.
Please contact your doctor emediately if you feel something is wrong...
after being vaccinated ... redness, swelling, headache... just to be on the safe side.
Read the PDF of CDC info for Vaccine safety
..........................................................................
(shown next)
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TipKat
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Posted: August 26 2009 at 1:33pm |
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Hi Mary, I also read yesterday that there is an experimental technique where they gave a liquid form of flu drug Relenza intravenously and saved a critically ill flu victims life. Here is the link: http://www.news.com.au/adelaidenow/story/0,22606,25950004-5006301,00.html
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dr d
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Posted: August 26 2009 at 1:39pm |
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Mary you read it correctlyy
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Dr d
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Mary008
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Posted: August 26 2009 at 7:42pm |
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.hi Doc. hope all is well on the front. ... thanks for the info Tipkat
Please excuse the brightness... It wouldn't unbold.
Cold Versus Flu
........................... >>>> From WebMD many thanks...
Influenza Info for Schools
............................................
..........
Mary008
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Mary008
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Posted: August 26 2009 at 8:47pm |
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Young Man In Australia Saved By ... Good Care and Relenza (zanamivir)
.......................................................................................................................................
Melbourne-based Biota, where zanamivir was originally developed
.......................................
Thanks To TipKat for the interesting story Link on the innovative Australian's in Melbourne
who came to the rescue of a patient who was nearly done in by the Swine Flu...
The 20 yr old young man was unable to take the medication any other way...so they
decided to give the drug Relenza intravenously.... now after 38 days the patient is
recovering.
...........................................................
read the article here-
Some background on Relenza (zanamivir )
.........................................................................
Melbourne, Australia -based Biota ( where zanamivir (Relenza) was originally developed.)
Biota, being only a small company, was not able to bring zanamivir to market by itself.
In 1990, zanamivir patent rights were licensed to Glaxo, now GlaxoSmithKline (GSK).
In 1999, the product was approved for marketing in the USA and subsequently has been
registered by GSK in a total of 70 countries (GlaxoSmithKline News release, 2006).
Zanamivir is delivered via Glaxo's proprietary Diskhaler inhalation device.
The license agreement entitled Biota to receive a 7% royalty on Glaxo's sales of
zanamivir. (Relenza)
Biota commenced legal proceedings in 2004 alleging that Glaxo's reduced marketing of zanamivir was a breach of contract. Biota claimed approximately A$700m from Glaxo. After
Biota spent four years trying to progress its case, and incurring A$50m in legal costs, the
company abandoned the claim in July 2008, recovering only A$20m including legal costs
following settlement at mediation. Biota had refused an earlier tactical offer from Glaxo of
A$75m plus legal costs.
According to the CDC, Tamiflu, zanamivir’s main competitor, is not as effective at treating the Influenza viruses as zanamivir, especially in H1N1 Seasonal Flu. In Fact, Tamiflu
showed that 99.6% of the tested strains of seasonal H1N1 flu were resistant to Tamiflu
while there have been absolutely zero flu samples seasonal or pandemic that show
resistance to zanamivir.[8]
In August 2006, Germany announced that it would buy 1.7 million doses of zanamivir, as part of its preparation strategy against bird flu. "Germany's purchase shows that countries
are starting to take a balanced view of influenza preparedness," says Simon Tucker, head
of research at Melbourne-based Biota, where zanamivir was originally developed.[7]
wikipedia
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Now At Level Six by Mary008 |
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Mary008
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Posted: August 27 2009 at 10:37am |
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Mary008
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Posted: August 28 2009 at 9:02am |
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some are rather strongly upset about Massachusetts slinking into the realm of ..
More Govt. than most of us can comprehend. (for a Cat 2 ish Pandemic?)
........................................................
(NaturalNews)
The United States of America is devolving into medical fascism and
Massachusetts is leading the way with the passage of a new bill, the "Pandemic Response
Bill" 2028, reportedly just passed by the MA state Senate and now awaiting approval in
the House. This bill suspends virtually all Constitutional rights of Massachusetts citizens
and forces anyone "suspected" of being infected to submit to interrogations,
"decontaminations" and vaccines.
It's also sets fines up to $1,000 per day for anyone who refuses to submit to quarantines, vaccinations, decontamination efforts or to follow any other verbal order by virtually any
state-licensed law enforcement or medical personnel.
You can read the text yourself here:
source-
Mary008
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Mary008
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Posted: August 28 2009 at 11:36pm |
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Please Discuss A Seasonal Flu Shot with Your Doctor
.......................................................................................
ECDC INTERIM RISK ASSESSMENT
Pandemic (H1N1) 2009 influenza 21 August 2009
excerpts- see source
page 5
There is a marked underrepresentation of infections in people over 65 years of age, who make up only 2% of reported cases. In Europe, among the reported cases the cases tend to be young: median age being 25 years in those who acquired the infection during travel, and 13 years in those domestically infected. Nearly 80% of cases are in individuals under 30 years of age [46,50,6,17,18] (see Figure 3).
page 6
The distribution of symptoms in Europe is very similar to that described from the USA, with the proportion of patients reporting gastrointestinal symptoms being 24% [18]. There are also preliminary reports that the incubation period may have a longer tail than usually observed. The results to date are: median 3–4 days, range 1–7 days [58]. page 7
2.2.5 Clinical attack rate4 In previous pandemics it was unusual to observe population clinical attack rates of less than 20%, while for seasonal influenza, rates are usually between 5% and 10% [28].
However, this pandemic may be unusual since it seems that older people may be missing from those infected. This notwithstanding, it will be safer to assume higher
attack rates of 30% as planning assumptions recognising that planning assumptions
represent the reasonable worse-case scenarios [20,52]. 4 ...The ‘clinical attack rate’ is the proportion of the population that is infected and has symptoms (i.e. asymptomatic infections are excluded). When considered for a pandemic, it can extend over the whole first wave period and mean the ‘cumulative attack rate’. The ‘hospitalisation rate’ is the proportion of those affected (with symptoms) that are ill enough to go to hospital, while the ‘case fatality rate’ is the proportion of those affected who die as a direct or indirect consequence of their infection.
page 8
...In Europe focal outbreaks in closed communities observed attack rates have been higher. In school outbreaks in the UK and France figures of around 30% and 50% have been reported [31,27]. No serological data are yet available. As is the case with other human influenza infections, there will probably be many mild and asymptomatic cases [17,28]. Certainly in New York most of those affected did not consult a doctor [55].
. ..Generally, as the focus of reporting moves from all cases to hospitalised cases, it can be expected that hospitalisation rates will seem to rise, but without any change in the underlying data. Therefore, at present, the 1–2% rate would seem a reasonable one to use for planning purposes. However, it always needs to be remembered that while national pandemic waves are spread out over three months, local waves are shorter and higher. This needs to be considered for planning local responses [36].
Please see Source... for complete Data... many thanks >>> to
note... Date of next planned update
1 September 2009 .......................................................
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Mary008 wrote: