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Mystery Illness Maryland Kills 75%.

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Albert View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 8:12am

Maryland flu deaths mysterious

Posted: Mar 8, 2012 8:56 AM by Sandra Young (CNN)

%20

(CNN) -- The Calvert County investigation into the flu deaths of 3 family members in Lusby, Maryland, found two of them--a 58 year-old brother and his 56-year-old-sister died of serious lung infections, a complication of seasonal flu.

The CDC already has confirmed the siblings died of influenza A. The strain is still unknown. Their 81-year-old mother, who was being cared for by her three children died at home Thursday of complications from the flu. The surviving sibling, a 51-year-old woman, remains in guarded condition at MedStar Washington Hospital Center in Washington, D.C., where she is responding to treatment.

Dr. David Rogers, Health Officer of Calvert County, says the investigation into the flu deaths of the three family members in Lusby, Maryland, is continuing. Rogers told CNN while unusual, these were isolated cases and the community at large should not be overly concerned or alarmed.

"This is extremely rare. I think what happened here is that we had an elderly woman who got flu, then she suffered a complication of flu, a severe bacterial pneumonia. Three kids came to provide bedside care and came in close contact. They may not only have caught flu from her but the serious lung infection that she had." Rogers said. "This is a very isolated situation where you have four people in a home, in close contact. This happens not infrequently in elderly people."

The Centers for Disease Control and Prevention estimates 90% of seasonal flu related deaths and more than 60% of flu related hospitalizations in the United States each year are in people 65 or older.

The sister of the deceased 81-year old woman is now also being treated for flu like symptoms at MedStar Washington Hospital Center.

Dr. Janis Orlowski, Senior Vice President and Chief Medical Officer at MedStar Washington Hospital Center, says the woman was admitted last night and is in fair condition.

"We don't yet know what this is about," Orlowski said. "She has a fever and a cough. They were all together at a funeral last week. Individuals could easily have caught the flu--a large gathering of people, hugging, consoling, possibly sharing a meal."

"If the individuals had the flu at that time it is quite likely that others are showing signs of the flu," says Orlowski. 'If I was in that family and felt ill, I would seek medical attention early."

Orlowski also treated the brother, who passed away at the hospital Monday night.

She says the bacterial infection they had was a staphylococcal (staph) infection, which she calls a super infection. Cultures on the surviving sister are not back yet. The source of the staph is still unknown, but Orlowski says the bacteria is naturally on the body. On skin, in the nose. Most people, she says, don't catch it from someone else.

"The question is did the mother have the staph where it went to the hands of the children and they got infected or did each end up becoming super infected with their own bacteria and we don't know the answer to that. It's likely we will never know."

And rare enough that they looked for other sources.

"We did look for poison, carbon monoxide in the house, did they all ingest something?" Orlowski asks. "It's astonishingly rare, such that we are all looking that other explanations."

Orlowski says over the last several days the hospital emergency room filled with nearly 400 patients. Most had chronic illnesses like heart failure, chronic obstructive pulmonary disease (COPD) and liver disease made worse by a bout of flu.

"It's flu season in the mid-Atlantic area so I urge the public to get vaccinated if you have not been, wash your hands, and if you are ill, don't go to school or work. We don't want you to spread the illness."

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Albert View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 9:15am
Not sure i ever mentioned this to you all.  Should this flu bug be h3n2v, or should h3n2v ever emerge, we can expect an uptick in traffic.  We launched h3n2v.org a few months ago with the purpose of redirecting people here.  Since it's the only h3n2v site currently on the net, it's already within the top 3 listings on google and yahoo. 
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anon54 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote anon54 Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 9:44am
Wasn't there a bird die off about a month ago in that general area? If memory serves me properly there was a very similar incident in Australia a few years ago, bird die off then several months later a very virulent round of flu went about.
Albert your remarks about seal die off and species jumping has given me the willies.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:05am
Still getting a lot of contradictions and conflicting stories. The victim's sister was described as being admitted for a fever but showing no other flu like symptoms, but fever is a defining symptom for flu, and now she has a cough. I guess the next few days will let us know if this is going anywhere, given the incubation period it seemed to show in the mother and siblings. What's the odds of the family not leaving the house to get supplies while they were caring for their mother? If it's still adapting and requires prolonged, close contact then we may be okay. Going to the store and running errands might not be enough for the virus to spread, but with the continued mention of the strain being "seasonal" that might not be the case. It may already be able to spread easily, but mutating to a higher mortality rate. We should get comfy, expect some more twists and turns before the truth outs, and keep our fingers crossed.
"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Mahshadin Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:11am
It seems implausible that they can not find out what kind of staff infection it is. It has been almost a week, they should know and yet all that is said in the releases is the doctor calling it a (Super Infection). What the BLANK kind of medical terminolgy is that. At most it would take around 3 days to find out exactly what it is and faster tests are less than 24 hours.
 
Sounds to me like this is being massaged by PR people, total lack of quality information!!!
 
 
"In a time of universal deceit, telling the truth is a revolutionary act."   G Orwell
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:23am
Hi Anon! long time no talk.  Good to see you. 
 
Mahshadin - I agree.  They should also know by now which h3 strain we're dealing with. If it was the regular seasonal h3n2, they could detect it quickly, and they would be fast to mention it. They could the also rule out a mutant swine flu or variant and could search for other factors. Since they're not mentioning regular seasonal h3n2, it leaves little doubt that it's a mutant flu, h3n2v.  
 
h3n2v is my guess, and they're hesitant on mentioning that a mutant flu has emerged. 
 
Jacksdad- good point.  Although if it is a new severe flu that hasn't quite gained efficient transmission, it still won't bode well for the future, and knowing that a new deadly flu is here to stay,  even via limited transmission.  This situation is about to spark A LOT of concern when they announce it.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote issapharma Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:25am
Hi, I'm news here from Paris,
 
LenaSun wrote:
12:32 PM EST

"This is Lena Sun, the reporter who's been writing about the health aspects of this story. To answer many of your questions--which are good!--Ruth Blake DID have a seasonal flu vaccine, according to David Rogers, the Calvert County health officer. None of the others were vaccinated, he said. This year the flu season has gotten off to a late start. All the health officials I've talked to are urging folks to get a flu shot if they haven't done so already".

http://www.washingtonpost.com/national/health-science/5th-calvert-family-member-at-hospital/2012/03/07/gIQAYZYFxR_allComments.html#comments
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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:30am
If it is bacterial and not viral, it's a really quick killer and spreads easily. Giving them the benefit of the doubt and assuming no cover up, it could be that what we're seeing is the bacteria going systemic and causing sepsis, which would possibly present as respiratory distress with pink, frothy sputum. That may explain the reports of the siblings coughing blood on arrival at the hospital. Still not sure we should be pinning all the blame on a bacterial infection though, especially as they were confirmed with influenza A.
"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:31am
Welcome to the forum issapharma.  That's good information and glad to have you here. 
 
 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote issapharma Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:32am
Originally posted by Albert Albert wrote:

Welcome to the forum issapharma.  That's good information and glad to have you here. 
 
 
Thank youSmile
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Post Options Post Options   Thanks (0) Thanks(0)   Quote anon54 Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:33am
I just read on another site that the members of the family attended a funeral on March 3 for a nephew. Clearly this may still be an active chain of transmission.Just watch and wait.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote issapharma Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:37am
The family members would have had two opportunities to be exposed. First at the nephew's funeral and then one of the other family members was also buried.
The link above is to the funeral home website.

http://sewellfuneralhome.com/
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Post Options Post Options   Thanks (0) Thanks(0)   Quote issapharma Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:41am

Growing H3  Maryland Death Cluster Raises Concerns
******** Commentary 12:00
March 8, 2012


"We don't yet know what this is about," Orlowski said. "She has a fever and a cough. They were all together at a funeral last week. Individuals could easily have caught the flu–a large gathering of people, hugging, consoling, possibly sharing a meal."

"If the individuals had the flu at that time it is quite likely that others are showing signs of the flu," says Orlowski. 'If I was in that family and felt ill, I would seek medical attention early."

The above
comments strongly suggest that the sister of the index case (81F) for the Calvert County, Maryland cluster is also infected by the H3 confirmed in her sister, nieces, and nephew.  This case raises serious concerns about the Calvert County announcement of no new cases or clusters, which appears to be dependent on lab confirmation and thus, is ignoring symptomatic contacts, include the above hospitalized case. 

Moreover, the above case has fever in cough, in contrast to media reports
claiming that the only symptom upon hospitalization was fever.

Moreover, the funeral cited above is almost certainly the
March 3 funeral (in Lusby) for a nephew, who was killed while falling a neighbor’s tree, also in Lusby.  Thus, the transmission chain appears to be active, and new cases should be developing symptoms this week.

More information on cases under investigation would be useful, as would detail on the H3 testing (which has been
withheld), including full sequences for all eight gene segments.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote issapharma Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:43am

Withheld Maryland Death Cluster Data Raises H3N2v Concerns
******** Commentary 15:00
March 8, 2012

Testing by the DHMH Laboratories Administration has confirmed that two of the cases had Influenza H3, a strain of Influenza A that has been circulating this season.

The above
comment from the DHMH press release updating the Calvert County, Maryland death cluster is carefully worded and does not say that the H3 is seasonal H3N2, and may in fact be H3 from H3N2v.  The state labs can only do PCR testing, which can produce a pattern (seasonal H3 and H1N1pdm NP positive) that is suggestive of H3N2v, but confirmation requires sequencing (which is done by the CDC).
 
Although there have not been any reported H3N2v cases in 2012, the second case in Indiana, the two cases in Maine, the three cases in Iowa, and the two cases in West Virginia were all from H3N2v circulating this season (and thus H3N2v has an H3 that has been circulating this season).

******** requested (via phone discussions and detailed e-mails sent yesterday morning) a clarification on PCR and/or sequencing result, and
neither DHMH nor the CDC has responded at this time. 

This failure to respond has increased concerns that the influenza H3 cited above is in fact H3 from H3N2v.

A response to the above written requests, as well as release of sequence data from isolates from the above cluster, would be useful.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote anon54 Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:46am
Hi and welcome issapharma,that was the article I read. I'm trying to keep a time line here. It just remains to be seen just how or if this develops.Given the family's position in the community there was probably a large funeral for both the index case and the nephew. I sincerely hope that I am way off base here but the implications are terrifying.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote issapharma Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:51am
Thanks,
 ( and sorry for my very bad english...)
 
THIS "H3" is certainly a new MUTATION more virulent of the flu A, but I do not think whether it is in their interest ( CDC ) to inform the public about it.


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Post Options Post Options   Thanks (0) Thanks(0)   Quote issapharma Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 10:59am
Three days ago, I have find an other strange news in Maryland, 45 miles from calvert county:
 
HYATTSVILLE, Md. (WUSA) -- On Monday, an emotional memorial service was held for a rising football star who died suddenly after complaining of chest problems this weekend.

Rico Webb was called "the gentle giant." The 6'7," 365 pound offensive lineman stood out as a powerhouse on the field, but was kind and mild-mannered in the hallways of Dematha High School where his classmates remembered him in tears and in laughs.

Classmate Lindell Fulsom said in tears during the memorial service for Webb, "Don't hide your love for somebody 'cause you never know when they'll be gone..."

Teammate Jason Dillon shared a memory that made the crowd laugh: "Sophmore year he got into a fight...it wasn't a massive fight or anything but it was big enough that it got a crowd around and it was pretty funny. This was right before practice. Coach...made him and James walk around for about 45 minutes. They walked around the entire field holding hands."

The high school senior left school Saturday with some flu-like symptoms. Later that night he complained of chest pains and died at the hospital...
 
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Post Options Post Options   Thanks (0) Thanks(0)   Quote anon54 Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 11:01am
Your English is fine . I tend to agree with you concerning the CDC. It will only be through vigilance by "civilians" such as the participants on this board will people know anything.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote jacksdad Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 11:06am
I read about the other death - about 40 miles away from the family cluster. No reports showing up on the internet of any new infections or clusters in the area as of this morning. Hopefully whatever it was (bacterial, viral or a combination) dead ended with the Calvert family.
"Buy it cheap. Stack it deep"
"Any community that fails to prepare, with the expectation that the federal government will come to the rescue, will be tragically wrong." Michael Leavitt, HHS Secretary.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Albert Quote  Post ReplyReply Direct Link To This Post Posted: March 08 2012 at 11:15am
The transmission threat is still relatively high as that surviving family member who is still in the hospital is sheding the virus, which generally lasts for 7 days.  Let's hope a nurse or doctor doesn't take the new bug home as she is not quarantined whatsoever.   The virus could spread significantly from her if they're not careful.
 
issapharma - i agree that it probably wouldn't be within their best interest to announce this new mutant flu, but they won't have a choice.  There are too many sites such as this one that are following it closely.  They won't have a choice.   
 
 
 
 
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