Tracking the next pandemic: Avian Flu Talk |
WHO is calling it |
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Kilt-3
Valued Member Since 2006 Joined: February 04 2015 Status: Offline Points: 1365 |
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Posted: March 20 2015 at 7:33pm |
The Egyptian H5N1 is close a pandemic strain now
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onefluover
Admin Group Joined: April 21 2013 Location: Death Valleyish Status: Offline Points: 20151 |
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From above:
WHO seeks vaccine viruses based on recent H5N1, H5N8 strains As part of its ongoing influenza pandemic preparedness efforts, the World Health Organization (WHO) is calling for the development of candidate vaccine viruses based on H5N1 viruses from recent human cases in Egypt and an H5N8 virus that was found in a wild bird in Washington state in December. In its Weekly Epidemiological Record, the WHO said recent H5N1 isolates from Egypt have accumulated enough mutations so that a vaccine based on a 2010 Egyptian H5N1 strain does not react very strongly with them, on the basis of tests in ferrets. The implication is that if the H5N1 strain now circulating in Egypt evolved into a pandemic virus, a vaccine based on the 2010 strain wouldn't work very well against it. The selection and development of candidate vaccine viruses is the first step toward vaccine production in case of a flu pandemic, but the steps do not imply a recommendation for actually starting production, the WHO noted. Governments can consider using the candidate viruses to make pilot batches of vaccine for clinical trials, depending on their perception of pandemic risk. Concerning recent H5N8 viruses, the WHO said their hemagglutinin (H) component belongs to the same clade (2.3.4.4) as that of recent H5N6 and H5N8 viruses from China and H5N6 viruses from Vietnam and Laos. A candidate vaccine virus for an H5N6 virus from China is now in development, it said. But in ferret tests, that candidate H5N6 vaccine strain did not react well with recent H5N8 and H5N2 isolates from the United States. Consequently the WHO said it is recommending development of a new candidate vaccine virus based on the H5N8 virus found in a captive gyrfalcon in Washington in December. Closely related H5N8 and H5N2 viruses have surfaced in a number of wild birds and poultry flocks in the United States recently. No human cases of H5N8 infection have been reported, but three human H5N6 cases have been reported in China. |
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"And then there were none."
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