Click to Translate to English Click to Translate to French  Click to Translate to Spanish  Click to Translate to German  Click to Translate to Italian  Click to Translate to Japanese  Click to Translate to Chinese Simplified  Click to Translate to Korean  Click to Translate to Arabic  Click to Translate to Russian  Click to Translate to Portuguese  Click to Translate to Myanmar (Burmese)

PANDEMIC ALERT LEVEL
123456
Forum Home Forum Home > Main Forums > Latest News
  New Posts New Posts RSS Feed - news on a possible vaccine-Please Read
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Tracking the next pandemic: Avian Flu Talk

news on a possible vaccine-Please Read

 Post Reply Post Reply
Author
Message
willow41 View Drop Down
Valued Member
Valued Member


Joined: January 27 2006
Location: United States
Status: Offline
Points: 109
Post Options Post Options   Thanks (0) Thanks(0)   Quote willow41 Quote  Post ReplyReply Direct Link To This Post Topic: news on a possible vaccine-Please Read
    Posted: February 06 2006 at 5:36am

I found an article on cnn.com yesterday saying they've created a vaccine against the bird flu.

http://www.cnn.com/2006/HEALTH/02/02/birdflu.vaccine.reut/in dex.html

please read the article and submit any comments you have on it.  do you think they've really created a useful vaccine?

Back to Top
Corn View Drop Down
Valued Member
Valued Member


Joined: December 13 2005
Location: United States
Status: Offline
Points: 1219
Post Options Post Options   Thanks (0) Thanks(0)   Quote Corn Quote  Post ReplyReply Direct Link To This Post Posted: February 06 2006 at 5:48am

I'm sure they have already in some form or another for the time being for a particular strain.  What they have of it will probably all go to the military.

Normal people will not see any vaccine for a year or more if we're lucky. Prepare to ride it out anyway.

Speculation is the only tool we have with a threat that can circle the globe in 30 days. Test results&news is slow.Factor in human conditions,politics, money&bingo!The truth!Facts come after the fact.
Back to Top
mightymouse View Drop Down
Valued Member
Valued Member
Avatar

Joined: January 27 2006
Status: Offline
Points: 487
Post Options Post Options   Thanks (0) Thanks(0)   Quote mightymouse Quote  Post ReplyReply Direct Link To This Post Posted: February 06 2006 at 5:51am
Most excellent.  Hope then can make it fast enough, in sufficient quantities, and available to all.   LOL!
Nothing matters - Therefore everything matters
Back to Top
Guests View Drop Down
Guest Group
Guest Group
Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: February 06 2006 at 6:01am


Experts Skeptical of Experimental Birdflu Vaccines

USA: February 6, 2006

WASHINGTON -" Two teams working on better vaccines for use against a
potential bird flu pandemic have announced progress in the past week,
but influenza experts are skeptical.

The two labs both used a human cold virus, called an adenovirus, to carry
pieces of DNA from H5N1 flu in a vaccine. Both labs - one at the US
Centers for Disease Control and Prevention and one at the University of
Pittsburgh Medical Center - were able to protect mice against fatal H5N1
infections.

But neither study was even mentioned at a meeting of top US flu experts
in Washington this week.

"It's just not that new," Dr. John Treanor, a flu vaccine expert at the
University of Rochester in New York, said in an interview. "There are a
zillion vaccines that protect in mice. On the grand scale of things, it's
nowhere near to being a vaccine you would see in humans."

But developing new vaccines is a time-consuming and tricky business,
and for the next few years the world is stuck with 40-year-old
technology, no matter what happens in the lab, the experts, including
manufacturers, said.

Researchers rely on an old-fashioned way of making vaccines against
influenza that requires the use of chicken eggs and months of cultivation.

Several companies and private labs are working on a vaccine against
H5N1. But because no one knows how it will mutate, they cannot be sure
that any vaccine made now would protect against whatever pandemic
strain eventually emerges.

Vaccines using cold viruses, using pure DNA, and using whole inactivated
viruses are all being tried.

But because they use completely novel technology, they would have to be
extensively tested in humans, who have different immune responses from
other animals.

Chris Viehbacher, President of GlaxoSmithKline, which makes flu
vaccines, said it would take years to approve entirely new approaches to
flu vaccine.

If a pandemic comes before vaccine technology can be improved, Glaxo
had counted on using the current vaccine formulation boosted with an
aluminum adjuvant, he said in an interview on Tuesday.

Adjuvants are added to vaccines to help increase the immune response
and may make it possible to stretch a vaccine supply.

Before boosting production and building new plants in the United States,
Viehbacher said drug makers wanted better protection from lawsuits from
people who may be harmed, or who may claim they were harmed, by
vaccines."

http://www.planetark.com/dailynewsstory.cfm/newsid/34875/
story.htm]http://www.planetark.com/dailynewsstory.cfm/newsi d/34875

Edited by Rick
Back to Top
merrittjohn View Drop Down
V.I.P. Member
V.I.P. Member


Joined: January 31 2006
Location: Afghanistan
Status: Offline
Points: 62
Post Options Post Options   Thanks (0) Thanks(0)   Quote merrittjohn Quote  Post ReplyReply Direct Link To This Post Posted: February 06 2006 at 6:11am
I saw this too.  And I'm very hopeful.  However,  this recombinant technology has been around for quite a while now.  My understanding is that they introduced the gene for haemagluten from H5N1 into an adenovirus.  They grow the adenovirus in a cell/tissue culture (very fast) and then the adenovirus is either 1) used to infect a person causing a common cold but confering some immunity to the haemagluten inserted or 2) destroyed but leaving all the viral DNA intact leading to a naked DNA vaccine that will confer immunity to the haemagluten.  Seems logical.... but I'm somewhat suspicious of the timing.  If I've got hte technicals wrong I'd love to be corrected. John.
willtolive
Back to Top
 Post Reply Post Reply
  Share Topic   

Forum Jump Forum Permissions View Drop Down