Tracking the next pandemic: Avian Flu Talk |
Swedish experts warn of new global bird flu virus |
Post Reply |
Author | |
Albert
Admin Joined: April 24 2006 Status: Offline Points: 47746 |
Post Options
Thanks(1)
Posted: July 21 2013 at 8:30am |
I believe the latest reported case was from Northern China, which is a first. Either way, when the temps drop, it's going to undoubtedly ignite.
Swedish experts warn of new global bird flu virus"The virus seems new to mankind. The entire world's population could be
affected if it gains momentum," said Annika Linde at Swedish Institute
for Communicable Disease Control (Smittskyddsinstitutet - SMI) to Sveriges Radio. http://www.thelocal.se/49144/20130719/ |
|
https://www.facebook.com/Avianflutalk
|
|
Albert
Admin Joined: April 24 2006 Status: Offline Points: 47746 |
Post Options
Thanks(1)
|
As the winter months grow near, you can expect the WHO to hype MERS pretty good to divert all attention off China. There is no way the WHO will ever address the potential threat of h7n9 with Margaret Chan in charge - and when it comes to the economic impact it could have on China. Chan allowed the cover up of SARS in 2003, as she will similarly do this winter with h7.
Should rename the WHO to World Economic Organization. |
|
https://www.facebook.com/Avianflutalk
|
|
cobber
Guest Group |
Post Options
Thanks(0)
|
Margaret Chan cover up?? And WHO hyping MERS?? I don't agree
My belief is China may be covering things up, but we just don't see the external cases outside of China backing up this assertion. China can't cover up media in the rest of the world. So on basic deduction we must take China at its word and believe it has H7N9 under control. If H7N9 was a pandemic emanating from China, we would see cases far spread in the developed world. This just isn't the case. It true to say it may develop over winter, but this is a maybe. The evidence so far indicates, H7N9 is poorly transmitted between humans and the most likely cause is from birds to humans. This is a worry but, not a get your guns size of concern. H7N9 map https://s.google.com/s/ms?ie=UTF8&authuser=0&hl=en&oe=UTF8&msa=0&msid=205430200180872645589.0004d962150bdee9261c0 - https://maps.google.com/maps/ms?ie=UTF8&authuser=0&hl=en&oe=UTF8&msa=0&msid=205430200180872645589.0004d962150bdee9261c0 Now contrast with MERS. We know that MERS transmits human to human quite easily. Some have argued we have already reached "sustained community transmission". I'm still sitting on the fence a little. Again you need to look at the evidence. MERS is travelling around the world something more akin to what you would see in a pandemic. It has easily jumped boarders, and has been popping up in the developed world. see map https://s.google.com/s/ms?authuser=0&vps=2&hl=en&ie=UTF8&oe=UTF8&msa=0&msid=205430200180872645589.0004dbdfc3c35db1c1518 - https://maps.google.com/maps/ms?authuser=0&vps=2&hl=en&ie=UTF8&oe=UTF8&msa=0&msid=205430200180872645589.0004dbdfc3c35db1c1518 MERS also Kills at a high rate. The key issue currently with MERS is understanding the problem. The WHO can't accurately test people on mass who have been exposed to the virus. They are battling many issues. The main one being consistency of positive identifications. The most accurate test method is a serum test, which is in drastically short supply. This is where i have an issue with the WHO's testing regime. Many health care workers have been found with asymptomatic cases, and there have been relatively few community based cases. This indicates that the testing serum is being used on these health care workers and the bigger picture of community based transmission isn't being revealed. The ramification of this is huge. Having a larger Asymptomatic base changes the spread potential dramatically. I believe quite the opposite about the WHO hyping MERS. I believe the WHO are understating the seriousness. They really can't afford to look foolish announcing another baseless emergency. They have made some dud calls in the past and this weighs heavily on their decision making. Also compound this with the pressure coming from managers of the worlds economy. Our global economy sits on a razors edge. The WHO are most likely getting pressure from all quarters to shut the hell up. Having said all this i still agree with their position of fence sitting. The ramifications of going to the public will cause chaos. |
|
Albert
Guest Group |
Post Options
Thanks(0)
|
Good post Cobber.
I still believe h7 has a much greater chance of spreading once winter arrives, and also believe it has a much greater chance of mutating/evolving - soon. The WHO should also have addressed the estimated 1500 - 20,000 cases of h7 in China, and those numbers seem like a much bigger threat than MERS this winter. WHO knows, correction, who knows.... they will both probably spread once winter arrives. SARS burnt itself out before winter had arrived in 2003. I believe coronaviruses and the flu both thrive in colder temps. Again - good post and thanks for the reply A |
|
LOPPER
Guest Group |
Post Options
Thanks(0)
|
It's the mutation rate of H7N9 which is 8 times the normal mutation rate of the average flu virus that makes it worrisome.
|
|
cobber
Guest Group |
Post Options
Thanks(0)
|
Mutation rate of H7N9 which is 8 times the normal mutation
I've heard other discussing this too, and don't get me wrong. I see H7N9 as a real threat i was just saying that the thing hasn't launched yet. I expect it could become human to human transmissible anytime. I also think that both viruses will get a boost this winter. What i was trying to communicate was MERS looks like it is launching now! No mutation needed. It may be on its way. The virus is moving outside boarders which is the key issue. Albert, where is these figure of 1500 - 20,000 H7 cases coming from? It seem very high. Is there are some crediable sources backing this up?
|
|
EdwinSm,
Moderator Joined: April 03 2013 Status: Offline Points: 24065 |
Post Options
Thanks(0)
|
A report in The Lancet (a leading British medical journal) eg one report on this " aving such a plan may be critical during the coming flu season. In an analysis published in the Lancet journal, researchers from the Chinese Center for Disease Control and Prevention in Beijing and from the University of Hong Kong reported that H7N9 infection was fatal in about a third of cases that are severe enough to require hospitalization. The H5N1 avian virus that caused a worldwide pandemic in 2003 had a 60% fatality risk for those hospitalized, while the more recent H1N1 flu was associated with a 21% risk of death for those seeking hospital care. The scientists based their H7N9 estimate on the number of people treated at hospitals throughout China, as well as information from their surveillance networks that monitor the volume of cases. Overall, they say that up to 3% of all people who became infected were at risk of dying from H7N9. .... “The mo[st] relevant finding, regarding implications for the coming
fall-winter, is that the clinical iceberg phenomenon that is common … of
most flu viruses applies to H7N9 as well. We estimated that between
1,500 and 27,000 symptomatic infections might have occurred in China,
compared to the 132 laboratory-confirmed cases,” says Leung." " |
|
Albert
Admin Joined: April 24 2006 Status: Offline Points: 47746 |
Post Options
Thanks(0)
|
The following from the article is also somewhat my opinion. Officials possibly have a small window to prepare before winter arrives, and it also appears that they're squandering their "advantage", although perhaps there is not a lot they can do - except to provide a little awareness so people can potentially prepare and know what to expect. Maybe that will have to be our role here? We'll know in about 60 - 90 days if a global disaster is imminent.
But even with new cases of H7N9 infection waning, the authors write that the off-season for the disease gives health care workers an advantage:
|
|
https://www.facebook.com/Avianflutalk
|
|
Albert
Admin Joined: April 24 2006 Status: Offline Points: 47746 |
Post Options
Thanks(0)
|
It's also worth noting that once winter arrives, h7n9 will be able still stick to surfaces for several days. I believe, but not 100% sure, that at 32 degrees h7 can stick to surfaces for approximately 1 week with no degradation.
Both MERS and H7N9 are far from being over. We're better off enjoying this summer as we never know when the crud could hit the fan as they say - and life as we know it may change. |
|
https://www.facebook.com/Avianflutalk
|
|
CStackDrPH
Valued Member Joined: April 21 2013 Status: Offline Points: 2308 |
Post Options
Thanks(0)
|
Good posts, everyone! We are speculating just like the professional epidemiologists!
Truth is, nobody knows what is likely to happen with any of these emerging viruses. Genetic analysis of the H7N9 virus shows that it has acquired key genetic changes that could facilitate human-to-human transmission: My guess is that H7N9 is going to emerge as a reassortment this flu season, after having wandered in the wilds of China for a while. It could be a nasty one. I'm not as concerned about MERS, it's a ferocious pathogen but we seem to be able to control killer coronaviruses better than influenza (longer incubation period for myxoviridae, easier transmission etc.). Hang in there, anything can happen, including emergence of a totally different influenza virus this winter! As I learn things from CDS and others, I'll share them. Thus far, local health departments are clueless in the USA. |
|
CRS, DrPH
|
|
KiwiMum
Chief Moderator Joined: May 29 2013 Status: Offline Points: 29680 |
Post Options
Thanks(0)
|
Albert, that's an interesting fact about H7 viruses being able to survive on surfaces.
I've always viewed the handle of shopping trolleys to be a source of infection but the other day I was in the supermarket and I watched a young male shelf stacker stop to pick his nose and eat it before continuing to stack tins on the shelf. Since the turnover of stock is so fast in a supermarket, it would be very easy to buy tins or bottles that have the live virus on them, take them home and infect who ever touches them. We learnt at school about the English town of Eame (i think that's right) where in order to stop the plague infecting their neighbours, they traded for food and left their money to pay for it in a running stream so that any infection would be washed away. I had always assumed that I would wear gloves, wash hands etc but it hadn't occurred to me that i may have to sterilize every thing that comes into our home.
|
|
Those who got it wrong, for whatever reason, may feel defensive and retrench into a position that doesn’t accord with the facts.
|
|
Guests
Guest Group |
Post Options
Thanks(0)
|
KiwiMum, I will have a pail with bleach water in it and dip every can into the pail then let it dry on my old cake racks. Germs are everywhere, I rinse my cans under running water now don't know if it removes much in germs, maybe I will start washing with hot water and antibacterial soap!
|
|
carbon20
Moderator Joined: April 08 2006 Location: West Australia Status: Offline Points: 65816 |
Post Options
Thanks(0)
|
an assessment of clinical severity
The Lancet, Volume 382, Issue 9887, Pages 138-145 Hongjie Yu, Benjamin J Cowling, Luzhao Feng, Eric HY Lau, Qiaohong Liao, Tim K Tsang, Zhibin Peng, Peng Wu, Fengfeng Liu, Vicky J Fang
You can get the full-text article here...
...if you are:
< id="article" name="article" ="/retrieve/logging" method="post">
AbstractSummaryBackgroundCharacterisation of the severity profile of human infections with
influenza viruses of animal origin is a part of pandemic risk
assessment, and an important part of the assessment of disease
epidemiology. Our objective was to assess the clinical severity of human
infections with avian influenza A H7N9 virus, which emerged in China in
early 2013.
MethodsWe obtained information about laboratory-confirmed cases of avian
influenza A H7N9 virus infection reported as of May 28, 2013, from an
integrated database built by the Chinese Center for Disease Control and
Prevention. We estimated the risk of fatality, mechanical ventilation,
and admission to the intensive care unit for patients who required
hospital admission for medical reasons. We also used information about
laboratory-confirmed cases detected through sentinel influenza-like
illness surveillance to estimate the symptomatic case fatality risk.
FindingsOf 123 patients with laboratory-confirmed avian influenza A H7N9
virus infection who were admitted to hospital, 37 (30%) had died and 69
(56%) had recovered by May 28, 2013. After we accounted for incomplete
data for 17 patients who were still in hospital, we estimated the
fatality risk for all ages to be 36% (95% CI 26–45) on admission to
hospital. Risks of mechanical ventilation or fatality (69%, 95% CI
60–77) and of admission to an intensive care unit, mechanical
ventilation, or fatality (83%, 76–90) were high. With assumptions about
coverage of the sentinel surveillance network and health-care-seeking
behaviour for patients with influenza-like illness associated with
influenza A H7N9 virus infection, and pro-rata extrapolation, we
estimated that the symptomatic case fatality risk could be between 160
(63–460) and 2800 (1000–9400) per 100 000 symptomatic cases.
InterpretationHuman infections with avian influenza A H7N9 virus seem to be less
serious than has been previously reported. Many mild cases might already
have occurred. Continued vigilance and sustained intensive control
efforts are needed to minimise the risk of human infection.
FundingChinese Ministry of Science and Technology; Research Fund for the
Control of Infectious Disease; Hong Kong University Grants Committee;
China–US Collaborative Program on Emerging and Re-emerging Infectious
Diseases; Harvard Center for Communicable Disease Dynamics; US National
Institute of Allergy and Infectious Disease; and the US National
Institutes of Health.
|
|
Everything we hear is an opinion, not a fact. Everything we see is a perspective, not the truth.🖖
Marcus Aurelius |
|
Post Reply | |
Tweet
|
Forum Jump | Forum Permissions You cannot post new topics in this forum You cannot reply to topics in this forum You cannot delete your posts in this forum You cannot edit your posts in this forum You cannot create polls in this forum You can vote in polls in this forum |