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Now tracking the new emerging South Africa Omicron Variant

New vaccines for yet unknown variants

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Dutch Josh View Drop Down
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    Posted: May 27 2021 at 2:37am

DJ This company [url]https://20medtx.com/therapeutic-applications/[/url] or https://20medtx.com/therapeutic-applications/ is working on newer vaccines that already can deal with most likely variants. 

Story in [url]https://www.ad.nl/binnenland/enschedees-bedrijf-ontwikkelt-vaccin-tegen-toekomstige-varianten-coronavirus~a8804c50/[/url] or https://www.ad.nl/binnenland/enschedees-bedrijf-ontwikkelt-vaccin-tegen-toekomstige-varianten-coronavirus~a8804c50/ via google translate;

The biomedical company 20MED Therapeutics from Enschede, together with the University of Twente and Wageningen University, will develop a vaccine against variants of the corona virus. 20MED develops so-called polymers that "deliver" medicines in the body to the place where they need to be. This also applies to the delivery of vaccines.

Gerben Kuitert 27-05-21, 06:22 Last update: 07:57
There are now six approved corona vaccines worldwide, with 86 more (!) In development. What 20Med and both universities thinks it will add to what is already there and what is still in the pipeline is a vaccine that anticipates corona variants that we do not even know yet. "We don't know what's coming, but we do know where those mutations in the virus will occur," says 20MED director Michiel Lodder. "That sounds a bit abstract, but if you know where the changes will appear, you can anticipate them in advance." And according to Lodder it is certain that new mutations are coming - outside the Brazilian, English, Indian and South African that we already know.
"Our technology is suitable"
20MED was founded in 2011 by UT professor Johan Engbersen, professor of biochemistry. “We want to prove that our technology is very suitable for making the vaccines,” says Lodder, director of 20Med. The basis of the technology that 20Med uses is the same that the manufacturers Pfizer and Moderna use in the production of their corona vaccines.

This involves so-called mRNA technology. "The difference between the vaccine that we are developing and that of Pfizer and Moderna is that the latter two manufacturers use tiny fat globules to deliver the vaccine into the cells, we use polymers for that," Lodder said. "The advantage of our technique is that you do not have to keep the vaccines at a temperature of -70 degrees, but that storage in a normal refrigerator is sufficient."

Selling technology
Lodder expects the new vaccine to be available within a year and a half. The vaccine from the eastern partners will be tested on Syrian hamsters available to Wageningen University. The provinces of Gelderland and Overijssel are subsidizing the research with 620,000 euros. It costs a total of 1.4 million euros. The remaining amount must be added by the parties themselves. 20Med can draw on the three million euros it collected from investors a few years ago. Lodder emphasizes that 20Med does not intend to produce the vaccines itself. If the technology is proven, it will be sold to a drug manufacturer.

Until last summer, 20MED was fully located in Enschede, but some of the twelve-member staff were forced to move to Leiden. This is due to the dire shortage of laboratory space at the University of Twente. There are plans to build a new laboratory at Kennispark, which could be rented by various spin-offs from the UT. We have to wait until the financing for the construction of the new lab is secured.

DJ The India variant now seems to be spreading in Australia, China...New vaccines may be needed. 

We cannot solve our problems with the same thinking we used when we created them.
~Albert Einstein
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