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Tracking the next pandemic: Avian Flu Talk

monolaurin?

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    Posted: January 30 2006 at 7:01pm

Has anyone had experience with Monolaurin?  It's supposedly a natural, holistic, anti-viral.

I have a friend that swares by this stuff... at least for combating the standard flu.



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It's not so much the apocalypse... but the credit card bills ;-)
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: January 30 2006 at 7:22pm

Sounds interesting, I have not come across this before. I will look into it further.  But here's what I found on a quick dig....

http://search.lef.org/cgi-src-bin/MsmGo.exe?grab_id=0&pa ge_id=2981&query=lauric%20acid&hiword=ACIDA%20ACIDAN %20ACIDAS%20ACIDBASED%20ACIDIC%20ACIDIS%20ACIDITY%20ACIDO%20 ACIDON%20ACIDS%20LAURI%20LAURIA%20acid%20lauric%20

Monolaurin (Glycerol Monolaurate)
Chemically, Monolaurin is a monoglycerol ester of the saturated fatty acid lauric acid. Lauric fatty acids are present in many animals and plants and possess broad-spectrum activity against fungi and viruses. Lauric acid is also present in human adipose tissue, urine, milk, and amniotic fluid; cow's milk, butter, margarine, and in palm-kernel and coconut oil. Esterification of lauric acid with glycerin yields compounds more active than the fatty acid alone.

Monolaurin had virucidal activity against 14 human enveloped RNA and DNA viruses. Monolaurin removed all measurable infectivity by disintegrating the viral envelope as evidenced by electron micrographs. By disrupting the conformation of the lipid bilayer (or the envelope), Monolaurin prevents viral attachment to susceptible host cells. Viruses that contain an envelope are termed enveloped , whereas those that lack an envelope are referred to as naked . DNA viruses (including herpes viruses) have a loose, outer envelope, which contains lipids. RNA viruses are similar in that they have a double outer envelope or bilayer which contains essential lipids and glycoproteins structurally embedded in this envelope. Solubilization of the lipids and phospholipids in the envelope are key mechanisms by which Monolaurin's virucidal activity is expressed. It was calculated that Monolaurin had a >99.9% success rate against all 14 viruses tested.

Although Monolaurin alone has no effect on lymphocyte or macrophage functions, it does potentiate immunological events initiated by other triggering agents (mitogens, antigens, phagocytic stimuli, and lymphokines). Monolaurin is regarded as a virustatic. Virustatic agents directly block replication of viruses, so there is no subsequent development of drug resistance, but do not kill the virus. Monolaurin is effective against HSV-1 and -2, EBV, and CMV (which share lipid envelope characteristics) (Cohen et al. 1977; Sands et al. 1979; Kabara, 1980; Kohn et al. 1980).

Monolaurin has antiviral properties that allows its use without significant toxicity. No significant abnormalities have been noted in liver enzymes, leukocytes, red cells, hematocrit, hemoglobin, or platelets with Monolaurin therapy.

A suggested Monolaurin dosage is 6 (300-mg) capsules daily on an empty stomach (20 minutes before or 2 hours after a meal).

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: January 30 2006 at 7:37pm

Influenza virus is an enveloped virus...

http://www.virology.net/Big_Virology/BVRNAortho.html

Taxonomy: Taxonomic structure of the family.
  • Genus Influenzavirus A
  • Genus Influenzavirus B
  • Genus Influenzavirus C
  • Genus "Thogoto-like Viruses"

Host: Virus infects vertebrates.

Genome: Virions contain 7 segments of to 8 segments of linear negative-sense single stranded RNA.

Total genome length is 12000-15000 nt. The largest segment 2300-2500 nt; of second largest 2300-2500 nt; of third 2200-2300 nt; of fourth 1700-1800 nt; of fifth 1500-1600 nt; of sixth 1400-1500 nt; of seventh 1000-1100 nt; of eighth 800-900 nt. Genome sequence has termina repeated sequences; repeated at both ends. Terminal repeats at the 5'-end 12-13 nucleotides long. Nucleotide sequences of 3'-terminus identical; the same in genera of same family; most on RNA (segments), or on all RNA species. Terminal repeats at the 3'-end 9-11 nucleotides long. Encapsidated nucleic acid solely genomic. Each virion contains defective interfering copies (may be present).

Morphology: Virions enveloped; pleomorphic and filamentous forms occur; spherical, or filamentous; 50-120 nm in diameter, or 20 nm in diameter; 200-300(-3000) nm long. Surface projections of envelope distinct; about 500 spikes (projecting 10-14 nm from the surface); dispersed evenly over all the surface (i.e. haemagglutininesterase (HEF)), or dispersed equally over all the surface, but the various types are in clusters (i.e. haemagglutinin (HA) the major glycoprotein is interposed irregularly by clusters of neuraminidase (NA), ratio of HA to NA about 4-5 to 1). Nucleocapsid(s) enclosed within lipoprotein membrane; nucleoproteins of different size classes with loop at each end; arrangement within virion uncertain. Nucleocapsids filamentous; with no clear modal length (of different size classes); 50-130 nm long; 9-15 nm in diameter. Symmetry helical.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote keegs2 Quote  Post ReplyReply Direct Link To This Post Posted: February 02 2006 at 7:30am
does that come over the counter or a script?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Spoon Quote  Post ReplyReply Direct Link To This Post Posted: February 02 2006 at 7:38am

It's OTC.  I purchased Monolaurin at VitaminShoppe.

It's not so much the apocalypse... but the credit card bills ;-)
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