...
What you don't know about whooping cough
Bordetella Pertussis .....................................
http://www.wannabee.org.au/archives/papers_research/Pertussis%20in%20adults.pdf - http://www.wannabee.org.au/archives/papers_research/Pertussis%20in%20adults.pdf
"...A prolonged cough alone is presumptively considered to be a case of pertussis during a known outbreak...."
Pertussis Infection in Adults
.......................................
SETH W. WRIGHT, MD, MPH, Nashville, Tenn
excerpts...
"...Nevertheless, it is now evident that, because of waning immunity from childhood vaccination, pertussis infection is common in adults. Physicians need to be familiar with pertussis in adults. Adults are the major reservoir of disease; susceptible infants may acquire pertussis not only from another child, but also from an infected adult...."
"...The disease is also costly since patients may be evaluated many times, may have expensive diagnostic tests done, and often are prescribed multiple courses of antibiotics..."
"...fact, more annual deaths were reported from pertussis than from meningitis, scarlet fever, measles, diphtheria, and poliomyelitis combined...."
"...The fact that pertussis is not solely a disease of children has been recognized for many years..."
......................................................................................................
According to the CDC.... There is no reliable measure of immunity to pertussis
The Vaccines don't seem to ...last.
........................................................................................................
http://www.emro.who.int/cbi/PDF/InterventionsMortality.pdf - http://www.emro.who.int/cbi/PDF/InterventionsMortality.pdf
Pertussis
There is no reliable measure of immunity to pertussis since it is difficult to determine the correlation between the levels of antibodies against specific pertussis antigens and level of protective immunity developed by animals or human subjects given the vaccine.
Furthermore,
the persistence of immunity to pertussis
following the three primary doses of the combination vaccine diphtheria, tetanus, pertussis (DTP)
is not well established.
A Finnish study following an outbreak
suggests that protection against pertussis conferred by the 3 doses given in infancy
lasts for about one year,
and protection following a fourth dose (booster) persists another
2 to 3 years (see reference 28).
.............................................................................................................
http://www.eurekalert.org/pub_releases/2004-02/uocm-adb021104.php - http://www.eurekalert.org/pub_releases/2004-02/uocm-adb021104.php
This work also points out "the importance of supporting a cadre of basic researchers," added Flicker, "who can quickly apply their expertise to national medical emergencies."
Tang's studies suggest that adefovir may also inhibit similar toxins produced by more common disease-causing bacteria including:
Bordetella pertussis, which causes whooping cough;
Yersinia pestis, which causes plague, and
Pseudomonas aeruginosa, a common cause of hospital-acquired infections and a scourge for patients with cystic fibrosis.
All three are also considered potential bioterror agents.
...........................................................................................................
http://gsbs.utmb.edu/microbook/ch007.htm - http://gsbs.utmb.edu/microbook/ch007.htm
Most bacterial pathogens do not invade cells, proliferating instead in the extracellular environment enriched by body fluids.
Some of these bacteria (e.g., V cholerae and Bordetella pertussis) do not even penetrate body tissues, but, rather, adhere to epithelial surfaces and cause disease by secreting potent protein toxins
..........................................................................................................................................
|