https://www.today.com/health/how-many-strains-covid-19-exist-covid-19-variant-guide-t207173" rel="external nofollow noopener" style="box-sizing: border-box; color: rgb(61, 101, 148); text-decoration: underline; background-color: rgb(255, 255, 255); font-size: 14px; - https://www.today.com/health/how-many-strains-covid-19-exist-covid-19-variant-guide-t207173 Early lab research on Pfizer's vaccine indicates that it https://www.reuters.com/article/us-health-coronavirus-pfizer-vaccine/pfizer-vaccine-only-slightly-less-effective-against-key-south-african-mutations-study-idUSKBN29W31M" rel="external nofollow noopener" style="box-sizing: border-box; color: inherit; text-decoration: underline; background-color: transparent; border-bottom: 1px solid rgb(255, 80, 60); - only slightly loses effectiveness against the South African variant , and https://www.nbcnews.com/health/health-news/pfizer-covid-vaccine-works-against-virus-variants-new-research-suggests-n1253475" rel="external nofollow noopener" style="box-sizing: border-box; color: inherit; text-decoration: underline; background-color: transparent; outline: 0px !important; border-bottom: 1px solid rgb(255, 80, 60); - previous research from the company on the U.K. variant https://investors.modernatx.com/news-releases/news-release-details/moderna-covid-19-vaccine-retains-neutralizing-activity-against" rel="external nofollow noopener" style="box-sizing: border-box; color: inherit; text-decoration: underline; background-color: transparent; border-bottom: 1px solid rgb(255, 80, 60); - Moderna said earlier this week that a lab study showed "no significant impact on neutralizing titers," which correlate to protection provided by a vaccination, against the U.K. strain. The study did find "a six-fold reduction in neutralizing titers" against the South African variant, but the company said the reduced titer levels are still expected to be protective. Plummer said her Cedars-Sinai team does not anticipate CAL.20C will evade the vaccines, but they're actively investigating to be sure. She also believes most other strains and mutations will respond to the existing vaccines. "It will become very difficult for SARS-CoV-2 at the rate that it's mutating to evade the vaccine," she said, adding that mRNA vaccines were chosen to fight this pandemic because they're "designed to overcome" mutations. Asked why Moderna and Pfizer would need to develop boosters if this is the case, Plummer said the scientific justification would be "an abundance of precaution."
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