[url]https://www.rfa.org/english/news/china/surge-12232021120335.html[/url] or https://www.rfa.org/english/news/china/surge-12232021120335.html - https://www.rfa.org/english/news/china/surge-12232021120335.html ; However, the city has also seen a growing number of hemorrhagic fever cases in recent weeks, according to media controlled by the ruling Chinese Communist Party (CCP). The Global Times, which has close ties to CCP mouthpiece the People's Daily, quoted a medical staff member at the infection unit of the First Affiliated Hospital of Xi'an Jiaotong University as saying that the hospital had admitted a patient with non-life-threatening hemorrhagic fever in the past few days. "Hemorrhagic fever is a common infectious disease in northern China," the paper said. "Starting from October every year, some areas of Shaanxi [of which Xi'an is the provincial capital] enter the high incidence season of hemorrhagic fever." The disease, also known as epidemic hemorrhagic fever, is caused by hantavirus, with rodents as the main source of infection, it said. Wang said some restrictions were already in place ahead of Thursday's lockdown, as China pursues a zero-COVID strategy ahead of the 2022 Winter Olympics in Beijing. "What I'm really worried about this time around is that we don't know how long this lockdown will go on for; there's the question of getting hold of supplies," she said. "Even if we can get them, the prices will go up." and [url]https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2#Genome[/url] or https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2#Genome - https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2#Genome ; SARS-CoV-2 has a linear, https://en.wikipedia.org/wiki/Sense_(molecular_biology)" style="text-decoration: none; color: rgb(6, 69, 173); background: none rgb(255, 255, 255); font-family: sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px;" title="Sense (molecular biology) - positive-sense , single-stranded RNA genome about 30,000 bases long. https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2#cite_note-V%E2%80%99kovskik:21-103" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [103] DJ Both CoVid-19 and the hanta virus [url]https://en.wikipedia.org/wiki/Orthohantavirus#Genome[/url] or https://en.wikipedia.org/wiki/Orthohantavirus#Genome - https://en.wikipedia.org/wiki/Orthohantavirus#Genome ; The genome of hantaviruses is https://en.wikipedia.org/wiki/Negative-sense_single-stranded_RNA_virus" style="text-decoration: none; color: rgb(6, 69, 173); background: none rgb(255, 255, 255); font-family: sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px;" title="Negative-sense single-stranded RNA virus - negative-sense, single-stranded RNA . are single-stranded RNA virusses (negative/positive related to the way they "turn"? ) [url]https://en.wikipedia.org/wiki/Sense_(molecular_biology)#RNA_sense_in_viruses[/url] or https://en.wikipedia.org/wiki/Sense_(molecular_biology)#RNA_sense_in_viruses ; RNA sense in viruses[ https://en.wikipedia.org/w/index.php?title=Sense_(molecular_biology)&action=edit§ion=6" style="text-decoration: none; color: rgb(6, 69, 173); background: none; white-space: nowrap;" title="Edit section: RNA sense in viruses - edit ]In https://en.wikipedia.org/wiki/Virology" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Virology - virology , the term "sense" has a slightly different meaning. The genome of an https://en.wikipedia.org/wiki/RNA_virus" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="RNA virus - RNA virus can be said to be either positive-sense, also known as a "plus-strand", or negative-sense, also known as a "minus-strand". In most cases, the terms "sense" and "strand" are used interchangeably, making terms such as "positive-strand" equivalent to "positive-sense", and "plus-strand" equivalent to "plus-sense". Whether a https://en.wikipedia.org/wiki/Virus#Genome" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Virus - viral genome is positive-sense or negative-sense can be used as a basis for classifying viruses. Positive-sense[ https://en.wikipedia.org/w/index.php?title=Sense_(molecular_biology)&action=edit§ion=7" style="text-decoration: none; color: rgb(6, 69, 173); background: none; white-space: nowrap;" title="Edit section: Positive-sense - edit ]Main article: https://en.wikipedia.org/wiki/Positive-sense_single-stranded_RNA_virus" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Positive-sense single-stranded RNA virus - Positive-sense single-stranded RNA virus Positive-sense ( https://en.wikipedia.org/wiki/5%E2%80%B2" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="5′ - 5′ -to- https://en.wikipedia.org/wiki/3%E2%80%B2" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="3′ - 3′ ) viral RNA signifies that a particular viral RNA sequence may be directly https://en.wikipedia.org/wiki/Translation_(biology)" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Translation (biology) - translated into viral proteins (e.g., those needed for viral replication). Therefore, in positive-sense RNA viruses, the viral RNA genome can be considered viral mRNA, and can be immediately translated by the host cell. Unlike negative-sense RNA, positive-sense RNA is of the same sense as mRNA. Some viruses (e.g. https://en.wikipedia.org/wiki/Coronaviridae" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Coronaviridae - Coronaviridae ) have positive-sense genomes that can act as mRNA and be used directly to synthesize proteins without the help of a complementary RNA intermediate. Because of this, these viruses do not need to have an https://en.wikipedia.org/wiki/RNA_polymerase" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="RNA polymerase - RNA polymerase packaged into the https://en.wikipedia.org/wiki/Virion" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Virion - virion —the RNA polymerase will be one of the first proteins produced by the host cell, since it is needed in order for the virus's genome to be replicated. Negative-sense[ https://en.wikipedia.org/w/index.php?title=Sense_(molecular_biology)&action=edit§ion=8" style="text-decoration: none; color: rgb(6, 69, 173); background: none; white-space: nowrap;" title="Edit section: Negative-sense - edit ]Main article: https://en.wikipedia.org/wiki/Negative-sense_single-stranded_RNA_virus" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Negative-sense single-stranded RNA virus - Negative-sense single-stranded RNA virus Negative-sense (3′-to-5′) viral RNA is complementary to the viral mRNA, thus a positive-sense RNA must be produced by an https://en.wikipedia.org/wiki/RNA-dependent_RNA_polymerase" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="RNA-dependent RNA polymerase - RNA-dependent RNA polymerase from it prior to translation. Like DNA, negative-sense RNA has a nucleotide sequence complementary to the mRNA that it encodes; also like DNA, this RNA cannot be translated into protein directly. Instead, it must first be transcribed into a positive-sense RNA that acts as an mRNA. Some viruses (e.g. https://en.wikipedia.org/wiki/Influenza" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Influenza - influenza viruses) have negative-sense genomes and so must carry an RNA polymerase inside the virion. DJ Can hanta-RNA recombine in any way with CoViD ? [url]https://www.globaltimes.cn/content/1183691.shtml[/url] or https://www.globaltimes.cn/content/1183691.shtml - https://www.globaltimes.cn/content/1183691.shtml (Chinese state media march 2020); Unlike COVID-19, hantavirus is not mainly transmitted through the respiratory system, but a patient's excreta and blood can be contagious, virologists said, after a Chinese worker died of the hantavirus on Monday.
News of the death from hantavirus amid the COVID-19 pandemic sparked widespread concern among netizens, with many worried that it would transmit between humans and become a double blow for humankind while the COVID-19 pandemic has yet to end.
The worker, surnamed Tian, planned to go back to Shandong to work along with 29 other people on a chartered bus on Monday, but began to feel unwell on the way and was sent to hospital in Ningshan county, Shannxi Province. Tian died despite treatment on Monday morning.
All the other passengers tested negative for the novel coronavirus and their test results for hantavirus are pending, Ningshan county government said on Wednesday.
It is unlikely that the patient infected his fellow passengers, even though they sat on the same bus, as infection does not usually occur between people. People are also not normally attacked by hantavirus and COVID-19 at the same time, Yang Zhanqiu, a virologist at Wuhan University, told the Global Times on Wednesday.
"Unlike the COVID-19, the hantavirus in most cases does not transmit through the respiratory system. But the human excreta and blood of an infected patient can transmit the virus to humans," Yang said.
Hantavirus, also known as epidemic hemorrhagic fever, or renal syndrome hemorrhagic fever, is an acute viral infectious disease mainly characterized by fever, tendency to bleed, and kidney damage.
The disease may be caused by contact with rats, eating food that they have touched, or breathing air contaminated by mouse feces. The disease is prevalent in villages from May to June and October to December, Yang said.
"There is no need to worry about the hantavirus. Hantavirus disease is preventable and controllable and there are vaccines to prevent it. Its incidence in urban cities is very low as the disease is mainly found in rural villages where rats tend to appear when people are working in the field," Yang explained.
The disease is prevalent in Eurasia, with cases of infection in Russia, Finland, Sweden, and China. The death rate from hantavirus infection in China stands between 1 percent and 10 percent while the death rate in the US is much higher, with an average of 40 percent, according to Yang.
Similar to COVID-19, the hantavirus can severely damage patients' liver, kidney and other organ functions and produce symptoms of fever and massive bleeding, Yang told the Global Times.
After the worker died of hantavirus, experts in Southwest China's Yunnan Province launched an epidemiological investigation. In the last five years, Southwest China's Yunnan Province has reported 1,231 patients with hantavirus. More than 200 cases are reported in Yunnan each year, news site thepaper.cn reported. DJ So hanta virus is spreading in a different way...I think however since CoViD and Hanta are related to rodents (as is Omicron) "rats, cats, pets" could be a factor to keep an eye on. A sort of mixing in non-human hosts may be more likely then seeing that in human hosts. Hanta-infection (in humans) most likely will be symptomatic-and thus be picked up. They most likely will check extra to see if the increase of Delta-CoViD AND Hanta in Xi'an may bring "unwelcome mixing"... [url]https://en.wikipedia.org/wiki/Orthohantavirus#Vaccine[/url] or https://en.wikipedia.org/wiki/Orthohantavirus#Vaccine - https://en.wikipedia.org/wiki/Orthohantavirus#Vaccine ; As of 2021, no vaccines against hantaviruses have been approved by the U.S. FDA, but whole virus https://en.wikipedia.org/wiki/Inactivated_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none rgb(255, 255, 255); font-family: sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px;" title="Inactivated vaccine - inactivated bivalent vaccines against Hantaan virus and Seoul virus are available in China and South Korea. In both countries, the use of the vaccine, combined with other preventive measures, has significantly reduced the incidence of hantavirus infections. Apart from these vaccines, four types of vaccines have been researched: DNA vaccines targeting the M genome segment and the S genome segment, subunit vaccines that use recombinant Gn, Gc, and N proteins of the virus, virus vector vaccines that have recombinant hantavirus proteins inserted in them, and virus-like particle vaccines that contain viral proteins, but lack genetic material. Of these, only DNA vaccines have entered into clinical trials. https://en.wikipedia.org/wiki/Orthohantavirus#cite_note-39" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [39] https://en.wikipedia.org/wiki/Orthohantavirus#cite_note-40" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [40] DJ So there are "tools"...
------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein
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