On vaccines...
Printed From: Avian Flu Talk
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Forum Name: General Discussion
Forum Description: (General discussion regarding the next pandemic)
URL: http://www.avianflutalk.com/forum_posts.asp?TID=44897
Printed Date: April 16 2024 at 10:41am
Topic: On vaccines...
Posted By: Dutch Josh
Subject: On vaccines...
Date Posted: July 20 2022 at 10:10pm
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DJ, There is -and should be- a lot of discussion on vaccines. In this CoViD pandemic vaccines may play a role, Discussion on what role, how, who pays what could/should maybe bring better stategies... I know not much of vaccines...just some basic info...Contact with weak or dead virus particles could start an immune response in a host...Those virus particles can be replaced by messanger RNA (m-RNA) to create a likewise reaction...as a basic idea as far as I understand it.... -Strategies; Of course history is full of diseases and pandemics....people did all kind of things "to try and limit risks"... Scapegoats, blaming some groups in the population, another country, is still very popular today but not very effective (and not science...). So in most of history there was a sort of selection; blame games started often by leaders that wanted to stay in position... non-pharma interventions by other "leaders"... -Non Pharma Interventions; Most of history people did not live with a pharma-industry producing vaccines, medication...limiting (close) contacts, all kind of protection-masks, incense, ginger etc had to offer protection...I think some of those steps became the basis of early medical, pharma science...thousends of years ago... Some diseases were caused by poison food, water...other diseases by infection...So a cure may work in some cases, not in others... Till this day Non pharma Interventions keep making sense; low budget, easy to do....problem is more how long to do it... The word quarantine comes from quarantena or quarantaine, meaning "forty days", used in the https://en.wikipedia.org/wiki/Venetian_language" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Venetian language - Venetian language in the 14th and 15th centuries and also in France. The word is designated in the period during which all ships were required to be isolated before passengers and crew could go ashore during the https://en.wikipedia.org/wiki/Black_Death" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Black Death - Black Death plague. The quarantena followed the trentino, or "thirty-day isolation" period, first imposed in 1347 in the https://en.wikipedia.org/wiki/Republic_of_Ragusa" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Republic of Ragusa - Republic of Ragusa , https://en.wikipedia.org/wiki/Dalmatia" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Dalmatia - Dalmatia (modern https://en.wikipedia.org/wiki/Dubrovnik" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Dubrovnik - Dubrovnik in Croatia). https://en.wikipedia.org/wiki/Quarantine#cite_note-JSM17-1" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [1] https://en.wikipedia.org/wiki/Quarantine#cite_note-Eccles-2" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [2] https://en.wikipedia.org/wiki/Quarantine#cite_note-Mayer-3" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [3] https://en.wikipedia.org/wiki/Quarantine#cite_note-EID2013-4" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [4] https://en.wikipedia.org/wiki/Merriam-Webster" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Merriam-Webster - Merriam-Webster gives various meanings to the noun form, including "a period of 40 days", several relating to ships, "a state of enforced isolation", and as "a restriction on the https://en.wikipedia.org/wiki/Freedom_of_movement" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Freedom of movement - movement of people and goods which is intended to prevent the spread of https://en.wikipedia.org/wiki/Disease" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Disease - disease or https://en.wikipedia.org/wiki/Pest_(organism)" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Pest (organism) - pests ". The word is also used as a verb. https://en.wikipedia.org/wiki/Quarantine#cite_note-5" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [5] Quarantine is distinct from https://en.wikipedia.org/wiki/Isolation_(health_care)" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Isolation (health care) - medical isolation , in which those confirmed to be infected with a communicable disease are isolated from the healthy population. https://en.wikipedia.org/wiki/Quarantine#cite_note-CDC-6" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [6] Quarantine may be used interchangeably with https://en.wikipedia.org/wiki/Cordon_sanitaire_(medicine)" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Cordon sanitaire (medicine) - cordon sanitaire , and although the terms are related, cordon sanitaire refers to the restriction of movement of people into or out of a defined geographic area, such as a community, in order to prevent an infection from spreading. https://en.wikipedia.org/wiki/Quarantine#cite_note-7" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [7] An early mention of isolation occurs in the https://en.wikipedia.org/wiki/Biblical" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Biblical - Biblical https://en.wikipedia.org/wiki/Book_of_Leviticus" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Book of Leviticus - book of Leviticus , written in the 7th century BC or perhaps earlier, which describes the procedure for separating out people infected with the skin disease https://en.wikipedia.org/wiki/Tzaraath" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Tzaraath - Tzaraath . The medical nature of this isolation is, however, disputed. As traditional exegesis (dated 700 CE) sees it as a punishment for trespassing one of several negative commandment, most notably https://en.wikipedia.org/wiki/Lashon_hara" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Lashon hara - Evil Speech . https://en.wikipedia.org/wiki/Quarantine#cite_note-8" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [8] A more recent hypothesis postulates that the infected are required to isolate themselves in order to prevent spread of disease[ https://en.wikipedia.org/wiki/Wikipedia:Citation_needed" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Wikipedia:Citation needed - Anyone with such a defiling disease must wear torn clothes, let their hair be unkempt, cover the lower part of their face and cry out, "Unclean! Unclean!" As long as they have the disease they remain unclean. They must live alone; they must live outside the camp DJ, In my view Non pharma Intervention is very effective still...In todays world with internet I think NPI should do the main job... It would need active governments, medical world defining ways of producing and logistics at the lowest possible pandemic risk. Asian countries may go for this strategy... End of part 1 |
Replies:
Posted By: Dutch Josh
Date Posted: July 20 2022 at 10:43pm
Adverse effects of COVID-19 vaccines and measures to prevent themRecently, The Lancet published a study on the effectiveness of COVID-19 vaccines and the waning of immunity with time. The study showed that immune function among vaccinated individuals 8 months after the administration of two doses of COVID-19 vaccine was lower than that among the unvaccinated individuals. According to European Medicines Agency recommendations, frequent COVID-19 booster shots could adversely affect the immune response and may not be feasible. The decrease in immunity can be caused by several factors such as N1-methylpseudouridine, the spike protein, lipid nanoparticles, antibody-dependent enhancement, and the original antigenic stimulus. These clinical alterations may explain the association reported between COVID-19 vaccination and shingles. As a safety measure, further booster vaccinations should be discontinued. In addition, the date of vaccination should be recorded in the medical record of patients. Several practical measures to prevent a decrease in immunity have been reported. These include limiting the use of non-steroidal anti-inflammatory drugs, including acetaminophen to maintain deep body temperature, appropriate use of antibiotics, smoking cessation, stress control, and limiting the use of lipid emulsions, including propofol, which may cause perioperative immunosuppression. In conclusion, COVID-19 vaccination is a major risk factor for infections in critically ill patients. DJ; Vaccines are NOT the "holy grail" ..do have (lots of) risks... In my view Non pharma Intervention should be the main-if not only-tool.... There are countries (Haïti, North Korea a.o.) claiming Non Pharma is effective...not because they did not want to go for vaccines, simply because most of the world did not get any vaccines.... -How vaccines are used; Big Pharma main goal is profit in most (western) countries....Even when a lot of work is funded by tax payers profit is #1.... Big Pharma has a very bad reputation on creating public health risks out of greed, testing on the poor in "countries we keep poor"... (High risk studies on "gain of functions" of virusses were transferred to countries with less strict rules. The Wuhan-lab some claim "leaked CoViD" did a study on corona virusses paid for by the US but outsourced to China for risk reasons...then starting some a "blame game"..."CCP-virus"...). The main goal in many (western) countries of medication, vaccines etc is profit... -Medical use; "Non Sterilizing" vaccines limit disease after infection...Sterilizing vaccines stop also the spread of disease... One of the main problems in CoViD is vaccinated people still getting infected. So you need a wider strategy also including Non Pharma Intervention....STOP THE SPREAD !!!! Because by now CoViD did see a selection process of mutations that did get better in evading immunity (both after earlier infection and vaccination). Over time vaccines are getting less and less effective in doing their job; limit disease....(they did not stop the infection from the start). Strategies on "vaccination only" with non-sterilizing vaccines during a pandemic are the best way to worsen a pandemic.... Vaccines at the start did offer good protection...but NOT stopping the spread made vaccines a danger not a help, a way out....Vaccination strategy was and is the main problem in my non-expert view... New (nasal) vaccines may offer help-a way out-ONLY !!! in combination with Non Pharma rules (masks, limits of contacts). DJ, The discussion on vaccines, pandemics, many other issues, did get "out of control"...In the US "everything became political" and that is not helping... Social science is needed to get effective communication started...Vaccines, medical world, has to serve public health not shareholders...other then we all being "shareholders" in a way public health is in the interests of us all... End of part 2 (of me trying to formulate my critical view on vaccines...Yes I did get 2x Pfizers, 2x Moderna...I do think vaccines have a good use...But I do disagree on making profits out of public healthcare...I think it is a governments job to have good public services and in return for offering those public services (not only healthcare but also housing, FREE !!! education, maybe even FREE-tax funded public transport...) ask for tax from that public... "Taxation without representation" is the outcome of neo-liberalism in wich governments offer hardly any public services (themselves) and tax money ends up at the 1%...further increasing socio-economic imbalance...This pandemic is political.... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: KiwiMum
Date Posted: July 21 2022 at 12:04am
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The real problem, in my opinion, is that the vast majority are completely over Covid. Most of us have had it and most of us recovered just fine. People just want to get on with their lives and put it behind them. Speaking for myself only I'll say that I don't want to wear a mask or have spaced seating. I've had Covid and my first reaction to a positive test was a split second of fear. The governments have done a good job in spreading the fear, but then I got a grip of myself and whilst I had it I logged my symptoms and those of my family and my conclusion was that yes we were ill, too ill to go to work and too ill to do anything much at all, but only for about 4 or 5 days, then we started to feel better. My children were quicker, and only ill for 3 days. I'm pretty sure we've just had the BA4 or 5 variant and it was like a nasty flu but quite short lived. I now consider us to be immune. I know that some people are catching it a second time but the only people I know who are doing that are fully vaccinated. We're strong and healthy. Been there, done that. And everyone my age feels the same. I know some older people who are frightened of it, but I have friends who are actively trying to catch it right now. So talk of non pharmaceutical interventions (NPI) is just irritating. It's a vote loser. Covid is rampant here but we're getting closer to the election and the government is losing popularity because it's interfering in our lives too much and affecting our businesses and right now, if it went to the vote, Labour would be out. I'm a grown up and I don't need mothering by Jacinda or anyone else. The governments of the world are turning their countries into nanny states and no one wants that. Personally I think they should abolish all restrictions and just let the individual take whatever precautions they feel are right for them. Covid is just like the flu, in fact, to me who has had both flu and Covid, I'd say they are indistinguishable, and both Covid and the flu can be fatal to the elderly, the weak and the immunocompromised and that's why that group of people get a flu shot every Autumn, but what we don't do is force everyone else to get a flu shot too. I'd rather have the flu and allow my immune system to flex it's muscles than have a flu shot. So yes Covid is killing some people, but so is the flu. As callous as this sounds, that's life I'm afraid. We need to move forward. ------------- Those who got it wrong, for whatever reason, may feel defensive and retrench into a position that doesn’t accord with the facts. |
Posted By: Dutch Josh
Date Posted: July 21 2022 at 1:48am
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KiwiMum, thanks for your reaction; Some points; -New Zealand did see at least 1,803 confirmed CoVid deaths so far...Global deaths at least [url]https://www.worldometers.info/coronavirus/[/url] or https://www.worldometers.info/coronavirus/ - https://www.worldometers.info/coronavirus/ at 6,4 million...real number may be several times that number.... However I think different countries can choose different roads...Countries could learn from each other. -How many people did get infected. Worldometers has 572 million "positive tests"....also real number will be much higher...Is it 2 billion out of the almost 8 billion people on this planet ? Maybe even 4 billion ? Or "only" 1 billion "humans" ? As far as I know over 100 non-human species may have tested positive... This CoViD pandemic is multi-species...making it even harder to control... -What role should governments play ? Good info could mean less government restrictions....I rather see good info-leaving people to make up their minds themselves....Freedom has responsability as the other side of that coin.... Like in the climate discussion however "freedom" should not mean destruction....Fossil fuel consumption has gone much to far much to long....A government can limit air travel to 5-10% of prepandemic...That at least would have some impact on both pandemics and climate change... Political parties going for "freedom" without accepting "responsability" as the other side destabilize "nature" and we are facing the consequences of that now.... In a good functioning democracy governments have a limited-balanced-role....NOT a "nanny-state"....but governments -governing- means setting rules...From taxation (a.o. to have healthcare) to a (sort of) prison/correction system...I think that is what a governments job is.... To fight pandemics (and other major problems; climate change, crime etc.) governments need public support... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: September 16 2022 at 1:52am
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Lots of questions on "new better-for profit (NOT public healthcare priority #1!!!) vaccines"; AbstractStudents at North American universities risk disenrollment due to third dose COVID-19 vaccine mandates. We present a risk-benefit assessment of boosters in this age group and provide five ethical arguments against mandates. We estimate that 22,000 - 30,000 previously uninfected adults aged 18-29 must be boosted with an mRNA vaccine to prevent one COVID-19 hospitalisation. Using CDC and sponsor-reported adverse event data, we find that booster mandates may cause a net expected harm: per COVID-19 hospitalisation prevented in previously uninfected young adults, we anticipate 18 to 98 serious adverse events, including 1.7 to 3.0 booster-associated myocarditis cases in males, and 1,373 to 3,234 cases of grade ≥3 reactogenicity which interferes with daily activities. Given the high prevalence of post-infection immunity, this risk-benefit profile is even less favourable. University booster mandates are unethical because: -1) no formal risk-benefit assessment exists for this age group; -2) vaccine mandates may result in a net expected harm to individual young people; -3) mandates are not proportionate: expected harms are not outweighed by public health benefits given the modest and transient effectiveness of vaccines against transmission; -4) US mandates violate the reciprocity principle because rare serious vaccine-related harms will not be reliably compensated due to gaps in current vaccine injury schemes; and -5) mandates create wider social harms. We consider counter-arguments such as a desire for socialisation and safety and show that such arguments lack scientific and/or ethical support. Finally, we discuss the relevance of our analysis for current 2-dose CCOVIDovid-19 vaccine mandates in North America. DJ-This US/UK study is devastating.....are humans (or countries) used a testcases for vaccines ? Some claim Israel was used to test Pfizer vaccines...since it did not have a VAERS/adverse reaction administration... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: September 22 2022 at 3:57am
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Questions on safety of vaccines did result in youtube warning/censorship...Totally unacceptable ! ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: September 22 2022 at 10:31pm
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Welcome good news; DJ, studies on nasal vaccines have been going on for two years...It may be able to get us out of this pandemic...(I hope !) ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: September 26 2022 at 9:54am
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More "nasal vaccine news"; SARS-CoV-2 positive participants initiating nasal irrigation were over 8 times less likely to be hospitalized than the national rate.
Rapid initiation of nasal saline irrigation to reduce severity in high-risk COVID+ outpatients
DJ, Nasal vaccines may-by technique- do better then traditional vaccinations in a muscle. ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: November 10 2022 at 2:27am
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Some latest info on vaccines [url]https://www.independentsage.org/demystifying-and-debunking-mrna-vaccines/[/url] or https://www.independentsage.org/demystifying-and-debunking-mrna-vaccines/ - https://www.independentsage.org/demystifying-and-debunking-mrna-vaccines/ DJ-Vaccines are just part of the story...If you want to see "CoViD as a flu" -and you also never go for flu-vaccines-I think you may be "double wrong"...but you have a right to choose... In my opinion CoViD-risks are increasing; -newer variants able to evade better immunity (from both earlier infection and/or vaccines) -CoViD may have long term health effects -new variants could cause infection in other/more parts of the body There was an "idea" CoViD would "become milder" over time-more cold like (maybe also based on idea's on the Russian 1890-flu-possibly being CoViD) however given the ongoing spread, extreme high numbers CoViD managed to get worse... So-even as vaccines never will be 100% perfect-balancing risks and gains may (again) move towards getting vaccinated... DJ-Even China has NO mandatory vaccinations (however testing may be mandatory)...so vaccines should ALWAYS be a choice-based on the best available info ! ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: badger2
Date Posted: November 10 2022 at 9:33am
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The Chinese military's SARS-like bat coronavirus, ZC45 spike protein, contains an RGD motif. SARS-CoV-2 spike protein RGD motif is at positions 403-405. HCov-229E coronavirus contains an RGD motif at positions 341-343. The RGD motif links to integrin binding. Here we link integrin binding to the glomerular basement membrane: Glomerular Basement Membrane-Derived Perlecan Inhibits Mesangial Cell Adhesion to Fibronectin https://pubmed.ncbi.nlm.nih.gov/8832207 '....The resulting avidity level is too low for mediating cell binding but sufficient to induce integrin organization into focal contacts.' 4 Nov 2022 A Population-Based Analysis of Risk of Glomerular Kidney Disease Relapse After COVID-19 Vaccination https://pubmed.ncbi.nlm.nih.gov/36332971 '....Glomerular kidney disease can worsen to complete kidney failure and dialysis, so the consequences are significant if there is a problem with mRNA, spike protein, and progression of disease.' To have left out the RGD motif in Pfizer mRNA vaccine would have been a mistake for Pfizer, and this motif in the mRNA "vaccine" is likely implicated in glomerular kidney disease exacerbation. ------------- Badger2 |
Posted By: Newbie1A
Date Posted: November 22 2022 at 8:18pm
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Food for thought... https://rumble.com/v1wac7i-world-premier-died-suddenly.html?fbclid=IwAR3XC6X-81Y8e00PR03O0Rrg_yxpzI9RDU-cbonLTQqKoifQCRSCf8MeBXg - World Premiere: Died Suddenly (rumble.com) https://rumble.com/v1wac7i-world-premier-died-suddenly.html?fbclid=IwAR3XC6X-81Y8e00PR03O0Rrg_yxpzI9RDU-cbonLTQqKoifQCRSCf8MeBXg - https://rumble.com/v1wac7i-world-premier-died-suddenly.html?fbclid=IwAR3XC6X-81Y8e00PR03O0Rrg_yxpzI9RDU-cbonLTQqKoifQCRSCf8MeBXg ------------- If it's to be - it's up to me! |
Posted By: Usk
Date Posted: November 23 2022 at 7:52am
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Please don’t post trash |
Posted By: KiwiMum
Date Posted: December 20 2022 at 10:30am
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Some vaccines are great. I've had most of them and so have my family, but the Covid "vaccines" aren't actually vaccines. They don't fit the description of a vaccine in almost all categories, but in particular, they do not stop the recipient catching the disease. It's a real shame that they used the word vaccine to describe this medical treatment as I feel it's pushed people's trust in vaccines backwards. ------------- Those who got it wrong, for whatever reason, may feel defensive and retrench into a position that doesn’t accord with the facts. |
Maxxx17 wrote:Posted By: Dutch Josh
Date Posted: December 24 2022 at 11:59am
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Vaccine injury is not a topic that should be casually censored by big tech. https://www.coronaheadsup.com/health/vaccine/vaccine-injured/the-vaccine-injured-are-the-most-hated-people-in-modern-society/" style="color: rgb(44, 51, 56); text-decoration: none;" target="_top - A member of the vaccine injured group UKCVFamily speaks out about her experiences following vaccination with the Astrazeneca Covid-19 vaccine. Isn’t about time we stopped gaslighting these innocent victims? … https://www.coronaheadsup.com/health/vaccine/vaccine-injured/the-vaccine-injured-are-the-most-hated-people-in-modern-society/" style="color: rgb(195, 196, 199); text-decoration: none;" target="_top - Continue reading DJ, I did not see all of the video yet...but most of the people seem to be pro-vaccine, pro-science...Only their healthissues are being denied, ignored...eventough they very likely will be linked to vaccines safe for most...but not all ! |
Posted By: Dutch Josh
Date Posted: December 24 2022 at 12:25pm
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[url]https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00768-4/fulltext[/url] or https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00768-4/fulltext ; CORRESPONDENCE| https://www.thelancet.com/journals/laninf/issue/vol22no1/PIIS1473-3099(21)X0013-8" style="box-sizing: border-box; background-color: transparent; cursor: pointer; color: var(--theme-font-color,#fff); text-decoration: none; border-bottom: 0.125rem solid rgba(255, 255, 255, 0.2); font-size: 0.875rem; opacity: 0.7; - VOLUME 22, ISSUE 1 , P16, JANUARY 01, 2022
Transmissibility of SARS-CoV-2 among fully vaccinated individualsVaccine effectiveness studies have conclusively demonstrated the benefit of COVID-19 vaccines in reducing individual symptomatic and severe disease, resulting in reduced hospitalisations and intensive care unit admissions. However, the impact of vaccination on transmissibility of SARS-CoV-2 needs to be elucidated. A prospective cohort study in the UK by Anika Singanayagam and colleagues regarding community transmission of SARS-CoV-2 among unvaccinated and vaccinated individuals provides important information that needs to be considered in reassessing vaccination policies. This study showed that the impact of vaccination on community transmission of circulating variants of SARS-CoV-2 appeared to be not significantly different from the impact among unvaccinated people., The scientific rationale for mandatory vaccination in the USA relies on the premise that vaccination prevents transmission to others, resulting in a “pandemic of the unvaccinated”. Yet, the demonstration of COVID-19 breakthrough infections among fully vaccinated health-care workers (HCW) in Israel, who in turn may transmit this infection to their patients, requires a reassessment of compulsory vaccination policies leading to the job dismissal of unvaccinated HCW in the USA. Indeed, there is growing evidence that peak viral titres in the upper airways of the lungs and culturable virus are similar in vaccinated and unvaccinated individuals.2,3,5–7 A recent investigation by the US Centers for Disease Control and Prevention of an outbreak of COVID-19 in a prison in Texas showed the equal presence of infectious virus in the nasopharynx of vaccinated and unvaccinated individuals. Similarly, researchers in California observed no major differences between vaccinated and unvaccinated individuals in terms of SARS-CoV-2 viral loads in the nasopharynx, even in those with proven asymptomatic infection. Thus, the current evidence suggests that current mandatory vaccination policies might need to be reconsidered, and that vaccination status should not replace mitigation practices such as mask wearing, physical distancing, and contact-tracing investigations, even within highly vaccinated populations. I declare no competing interests. - https://twitter.com/LongDesertTrain" style="background-color: rgba(0, 0, 0, 0); color: inherit; font: inherit; list-style: none; margin: 0px; text-align: inherit; text-decoration: none; cursor: pointer; -webkit-box-align: stretch; -webkit-box-direction: normal; -webkit-box-orient: vertical; align-items: stretch; border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; min-height: 0px; min-width: 0px; padding: 0px; position: relative; z-index: 0; max-width: 100%; outline-style: none; - https://twitter.com/LongDesertTrain" style="background-color: rgba(0, 0, 0, 0); color: inherit; font: inherit; list-style: none; margin: 0px; text-align: inherit; text-decoration: none; cursor: pointer; -webkit-box-align: stretch; -webkit-box-direction: normal; -webkit-box-orient: vertical; align-items: stretch; border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; min-height: 0px; min-width: 0px; padding: 0px; position: relative; z-index: 0; max-width: 100%; outline-style: none;" tabindex="-1 - I found the most extreme example yet a few days ago: a BA.2 with 137 private mutations—134 of them transitions, the type that molnupiravir is known to induce. There can be little doubt this is a molnupiravir creation. DJ, It may be to early to state vaccines, anti-virals may have worsened the pandemic. It may have resulted in creating more variants. In that way-on the short term vaccines may have saved millions of lives...to see that effect undone on the longer term...???? ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: December 26 2022 at 11:59pm
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Dr. John Campbell [url]https://www.youtube.com/watch?v=AYiwms-Yp5s[/url] or https://www.youtube.com/watch?v=AYiwms-Yp5s - https://www.youtube.com/watch?v=AYiwms-Yp5s on the "Moderna-deal"..... Full video first posted 24th December 2022. Moderna Chief Executive Stephane Bancel https://www.cnbc.com/2022/06/22/moder... That capacity that we’re building in the UK, that they are committed to buying the product for the next ten years NOTES TO EDITORS: the details of the strategic partnership between the government and Moderna are commercially sensitive UK, Prime Minister, Moderna (2020) https://www.theguardian.com/politics/... Mr. Sunak refused to disclose whether he will profit from a surge in the share price of Moderna Theleme has a $500m investment in US-based Moderna Mr. Sunak was a founding partner of Theleme Partners and one of the executives managing its US office. He left the firm in 2013 Theleme is registered in the Cayman Islands (which does not make company records public) Moderna goes global https://globalnews.ca/news/9258211/gr... Canada New factory in Montreal area, Laval, Que Mr. Trudeau took part in a groundbreaking ceremony Completed in 2024 or 2025 mRNA vaccines, 100 million doses per year Covid, influenza, respiratory syncytial virus Innovation Minister François-Philippe Champagne Canada committed to purchase a certain number of vaccines Part of a seven-year agreement 200+ workforce No to leave out Moderna, Inc. ( https://en.wikipedia.org/wiki/Help:IPA/English" style="text-decoration: none !important; color: rgb(6, 69, 173); background: none;" title="Help:IPA/English - / - m - ˈ - ɜːr - ə/ https://en.wikipedia.org/wiki/Help:Pronunciation_respelling_key" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Help:Pronunciation respelling key - - DUR-nə ) https://en.wikipedia.org/wiki/Moderna#cite_note-4" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [4] is an American pharmaceutical and https://en.wikipedia.org/wiki/Biotechnology" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Biotechnology - biotechnology company based in https://en.wikipedia.org/wiki/Cambridge,_Massachusetts" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Cambridge, Massachusetts - Cambridge, Massachusetts that focuses on https://en.wikipedia.org/wiki/RNA_therapeutics" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="RNA therapeutics - RNA therapeutics , primarily https://en.wikipedia.org/wiki/MRNA_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="MRNA vaccine - mRNA vaccines . These https://en.wikipedia.org/wiki/Vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Vaccine - vaccines use a copy of a molecule called https://en.wikipedia.org/wiki/Messenger_RNA" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Messenger RNA - messenger RNA (mRNA) to produce an https://en.wikipedia.org/wiki/Immune_response" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Immune response - immune response . https://en.wikipedia.org/wiki/Moderna#cite_note-5" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [5] https://en.wikipedia.org/wiki/Moderna#cite_note-10K-1" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [1] The company's only commercial product is the https://en.wikipedia.org/wiki/Moderna_COVID-19_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Moderna COVID-19 vaccine - Moderna COVID-19 vaccine , marketed as Spikevax. As of 2022, the company has 44 treatment and vaccine candidates, of which 21 have entered https://en.wikipedia.org/wiki/Clinical_trial" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Clinical trial - clinical trials . Targets for vaccine candidates include https://en.wikipedia.org/wiki/Influenza" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Influenza - influenza , https://en.wikipedia.org/wiki/HIV" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="HIV - HIV , https://en.wikipedia.org/wiki/Respiratory_syncytial_virus" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Respiratory syncytial virus - respiratory syncytial virus , https://en.wikipedia.org/wiki/Epstein%E2%80%93Barr_virus" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Epstein–Barr virus - Epstein–Barr virus , the https://en.wikipedia.org/wiki/Nipah_virus" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Nipah virus - Nipah virus , https://en.wikipedia.org/wiki/Chikungunya" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Chikungunya - chikungunya , a combined single-shot https://en.wikipedia.org/wiki/COVID-19" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="COVID-19 - COVID-19 booster and https://en.wikipedia.org/wiki/Influenza_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Influenza vaccine - influenza vaccine , a https://en.wikipedia.org/wiki/Cytomegalovirus_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Cytomegalovirus vaccine - cytomegalovirus vaccine , and two https://en.wikipedia.org/wiki/Cancer_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Cancer vaccine - cancer vaccines . The company's pipeline also includes candidates for https://en.wikipedia.org/wiki/Cancer_immunotherapy" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Cancer immunotherapy - cancer immunotherapy using https://en.wikipedia.org/wiki/OX40_ligand" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="OX40 ligand - OX40 ligand , https://en.wikipedia.org/wiki/Interleukin_23" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Interleukin 23 - interleukin 23 , https://en.wikipedia.org/wiki/IL36G" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="IL36G - IL36G , and https://en.wikipedia.org/wiki/Interleukin_12" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Interleukin 12 - interleukin 12 as well as, in partnership with https://en.wikipedia.org/wiki/AstraZeneca" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="AstraZeneca - AstraZeneca , a https://en.wikipedia.org/wiki/Regenerative_medicine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Regenerative medicine - regenerative medicine treatment that encodes https://en.wikipedia.org/wiki/Vascular_endothelial_growth_factor_A" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Vascular endothelial growth factor A - vascular endothelial growth factor A to stimulate https://en.wikipedia.org/wiki/Blood_vessel" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Blood vessel - blood vessel growth for patients with https://en.wikipedia.org/wiki/Myocardial_ischemia" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Myocardial ischemia - myocardial ischemia . https://en.wikipedia.org/wiki/Moderna#cite_note-10K-1" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [1] - NIH vaccine patent dispute[ https://en.wikipedia.org/w/index.php?title=Moderna&action=edit§ion=15" style="text-decoration: none; color: rgb(6, 69, 173); background: none; white-space: nowrap;" title="Edit section: NIH vaccine patent dispute - edit ]Moderna is involved in a patent dispute with the https://en.wikipedia.org/wiki/National_Institutes_of_Health" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="National Institutes of Health - NIH over its COVID-19 vaccine. https://en.wikipedia.org/wiki/Moderna#cite_note-59" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [58] According to the NIH, three of its scientists played a major role in developing the vaccine over four years of collaboration. https://en.wikipedia.org/wiki/Moderna#cite_note-60" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [59] https://en.wikipedia.org/wiki/Moderna#cite_note-robbins-61" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [60] After first refuting the shared patent application entirely, Moderna postponed the final payment for filing the application, thereby leaving the patent application unfiled as of December 2021. https://en.wikipedia.org/wiki/Moderna#cite_note-robbins-61" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [60] Pfizer and BioNTech patent lawsuits[ https://en.wikipedia.org/w/index.php?title=Moderna&action=edit§ion=16" style="text-decoration: none; color: rgb(6, 69, 173); background: none; white-space: nowrap;" title="Edit section: Pfizer and BioNTech patent lawsuits - edit ]On August 26, 2022, Moderna sued https://en.wikipedia.org/wiki/Pfizer" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Pfizer - Pfizer and https://en.wikipedia.org/wiki/BioNTech" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="BioNTech - BioNTech in both Massachusetts and Germany, accusing the https://en.wikipedia.org/wiki/Pfizer%E2%80%93BioNTech_COVID-19_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Pfizer–BioNTech COVID-19 vaccine - Pfizer–BioNTech COVID-19 vaccine of violating the patent on Moderna's https://en.wikipedia.org/wiki/MRNA_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="MRNA vaccine - mRNA vaccine technology. https://en.wikipedia.org/wiki/Moderna#cite_note-62" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [61] Operation Warp Speed (OWS) was a https://en.wikipedia.org/wiki/Public%E2%80%93private_partnership" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Public–private partnership - public–private partnership initiated by the United States government to facilitate and accelerate the development, manufacturing, and distribution of https://en.wikipedia.org/wiki/COVID-19_vaccine" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="COVID-19 vaccine - COVID-19 vaccines , therapeutics, and diagnostics. https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-hhs-1" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [1] https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-facts-2" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [2] The first news report of Operation Warp Speed was on April 29, 2020, https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-armstrong-3" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [3] https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-cohen-4" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [4] https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-sanger-5" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [5] and the program was officially announced on May 15, 2020. https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-hhs-1" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [1] It was headed by https://en.wikipedia.org/wiki/Moncef_Slaoui" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Moncef Slaoui - Moncef Slaoui from May 2020 to January 2021 and by https://en.wikipedia.org/wiki/David_A._Kessler" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="David A. Kessler - David A. Kessler from January to February 2021. https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-6" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [6] At the end of February 2021, Operation Warp Speed was transferred into the responsibilities of the https://en.wikipedia.org/wiki/White_House_COVID-19_Response_Team" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="White House COVID-19 Response Team - White House COVID-19 Response Team . https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-zraick-7" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [7] The program promoted mass production of multiple vaccines, and different types of vaccine technologies, based on preliminary evidence, allowing for faster distribution if clinical trials confirm one of the vaccines is safe and effective.[ https://en.wikipedia.org/wiki/Wikipedia:Citation_needed" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Wikipedia:Citation needed - https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-jacobs-8" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [8] Operation Warp Speed, initially funded with about $10 billion from the https://en.wikipedia.org/wiki/CARES_Act" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="CARES Act - CARES Act (Coronavirus Aid, Relief, and Economic Security) passed by the https://en.wikipedia.org/wiki/United_States_Congress" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="United States Congress - United States Congress on March 27, 2020, https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-hhs-1" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [1] was an interagency program that includes components of the https://en.wikipedia.org/wiki/Department_of_Health_and_Human_Services" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Department of Health and Human Services - Department of Health and Human Services , including the https://en.wikipedia.org/wiki/Centers_for_Disease_Control_and_Prevention" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Centers for Disease Control and Prevention - Centers for Disease Control and Prevention , https://en.wikipedia.org/wiki/Food_and_Drug_Administration" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Food and Drug Administration - Food and Drug Administration , the https://en.wikipedia.org/wiki/National_Institutes_of_Health" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="National Institutes of Health - National Institutes of Health , and the https://en.wikipedia.org/wiki/Biomedical_Advanced_Research_and_Development_Authority" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="Biomedical Advanced Research and Development Authority - Biomedical Advanced Research and Development Authority (BARDA); the https://en.wikipedia.org/wiki/United_States_Department_of_Defense" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="United States Department of Defense - Department of Defense ; private firms; and other federal agencies, including the https://en.wikipedia.org/wiki/United_States_Department_of_Agriculture" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="United States Department of Agriculture - Department of Agriculture , the https://en.wikipedia.org/wiki/United_States_Department_of_Energy" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="United States Department of Energy - Department of Energy , and the https://en.wikipedia.org/wiki/United_States_Department_of_Veterans_Affairs" style="text-decoration: none; color: rgb(6, 69, 173); background: none;" title="United States Department of Veterans Affairs - Department of Veterans Affairs . https://en.wikipedia.org/wiki/Operation_Warp_Speed#cite_note-hhs-1" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [1] DJ...so billions of US taxpayersmoney ended up in a for profit commercial new pharma producer signing exclusive contracts (excluding other vaccines-the number of Moderna vaccine leave no room for other vaccines...) with UK, Canada, Australia government. Billions go to "share holders" (including the UK PM ????)... This is NOT the way to restore trust in either politics or vaccines.... DJ-Vaccines did save billions of lives since introduction. Vaccines against all kinds of diseases are needed at a certain level to keep those diseases under control. "Only for profit pharma" is destroying trust in ALL vaccines.... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: December 31 2022 at 2:34am
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Dr. John Campbell trying to make up his mind on the safety of m-RNA vaccines; [url]https://www.youtube.com/watch?v=JYR1wz-Cf_M&t=608s[/url] or https://www.youtube.com/watch?v=JYR1wz-Cf_M&t=608s - https://www.youtube.com/watch?v=JYR1wz-Cf_M&t=608s ; Rotavirus vaccine Rotashield, (1999),1 to 2 serious events per 10,000 vaccinees, Vaccine withdrawn Covid mRNA vaccines, 1 serious event per 800 vaccinees, Vaccine officially promoted Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults DJ-links [url]https://pubmed.ncbi.nlm.nih.gov/36055877/[/url] or https://pubmed.ncbi.nlm.nih.gov/36055877/ - https://pubmed.ncbi.nlm.nih.gov/36055877/ and [url]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428332/[/url] or https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428332/ - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428332/ (full text); AbstractIntroduction: In 2020, prior to COVID-19 vaccine rollout, the Brighton Collaboration created a priority list, endorsed by the World Health Organization, of potential adverse events relevant to COVID-19 vaccines. We adapted the Brighton Collaboration list to evaluate serious adverse events of special interest observed in mRNA COVID-19 vaccine trials. Methods: Secondary analysis of serious adverse events reported in the placebo-controlled, phase III randomized clinical trials of Pfizer and Moderna mRNA COVID-19 vaccines in adults ( http://clinicaltrials.gov/show/NCT04368728" style="box-sizing: inherit; background-color: transparent; color: rgb(0, 113, 188); text-decoration: none;" title="See in ClinicalTrials.gov - NCT04368728 and http://clinicaltrials.gov/show/NCT04470427" style="box-sizing: inherit; background-color: transparent; color: rgb(0, 113, 188); text-decoration: none;" title="See in ClinicalTrials.gov - NCT04470427 ), focusing analysis on Brighton Collaboration adverse events of special interest. Results: Pfizer and Moderna mRNA COVID-19 vaccines were associated with an excess risk of serious adverse events of special interest of 10.1 and 15.1 per 10,000 vaccinated over placebo baselines of 17.6 and 42.2 (95 % CI -0.4 to 20.6 and -3.6 to 33.8), respectively. Combined, the mRNA vaccines were associated with an excess risk of serious adverse events of special interest of 12.5 per 10,000 vaccinated (95 % CI 2.1 to 22.9); risk ratio 1.43 (95 % CI 1.07 to 1.92). The Pfizer trial exhibited a 36 % higher risk of serious adverse events in the vaccine group; risk difference 18.0 per 10,000 vaccinated (95 % CI 1.2 to 34.9); risk ratio 1.36 (95 % CI 1.02 to 1.83). The Moderna trial exhibited a 6 % higher risk of serious adverse events in the vaccine group: risk difference 7.1 per 10,000 (95 % CI -23.2 to 37.4); risk ratio 1.06 (95 % CI 0.84 to 1.33). Combined, there was a 16 % higher risk of serious adverse events in mRNA vaccine recipients: risk difference 13.2 (95 % CI -3.2 to 29.6); risk ratio 1.16 (95 % CI 0.97 to 1.39). Discussion: The excess risk of serious adverse events found in our study points to the need for formal harm-benefit analyses, particularly those that are stratified according to risk of serious COVID-19 outcomes. These analyses will require public release of participant level datasets. DJ, One has to balance risks of vaccines/interventions with the risk of "problems", solutions have to be proportionate. Also "do no harm" medical ethics.... I-and Dr.J.C.-am not an immunologist/expert... The definition of a serious adverse event (SAE) was provided in each trial’s study protocol and included in the supplemental material of the trial’s publication. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428332/#b0010" style='box-sizing: inherit; background-color: rgb(255, 255, 255); color: rgb(55, 111, 170); text-decoration: underline; font-family: Cambria, "Cambria Math", stixgeneral, "Times New Roman", Times, serif; font-size: 20px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px;'>[2] , https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428332/#b0015" style='box-sizing: inherit; background-color: rgb(255, 255, 255); color: rgb(55, 111, 170); text-decoration: underline; font-family: Cambria, "Cambria Math", stixgeneral, "Times New Roman", Times, serif; font-size: 20px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px;'>[3] , https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9428332/#b0020" style='box-sizing: inherit; background-color: rgb(255, 255, 255); color: rgb(55, 111, 170); text-decoration: underline; font-family: Cambria, "Cambria Math", stixgeneral, "Times New Roman", Times, serif; font-size: 20px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px;'>[4] Pfizer and Moderna used nearly identical definitions, consistent with regulatory expectations. An SAE was defined as an adverse event that results in any of the following conditions: death; life-threatening at the time of the event; inpatient hospitalization or prolongation of existing hospitalization; persistent or significant disability/incapacity; a congenital anomaly/birth defect; medically important event, based on medical judgment. DJ..If 1 in 800 vaccines results in these "Serious Adverse Events" then repeating those vaccines-boosters increases risks. Does this mean 5 vaccinations results in (long term) risks of 1 in 160 ? The Pfizer and Moderna trials are expected to follow participants for two years. Within weeks of the emergency authorization, however, the sponsors began a process of unblinding all participants who elected to be unblinded. In addition, those who received placebo were offered the vaccine. These self-selection processes may have introduced nonrandom differences between vaccinated and unvaccinated participants, thus rendering the post-authorization data less reliable. Therefore, to preserve randomization, we used the interim datasets that were the basis for emergency authorization in December 2020, approximately 4 months after trials commenced. DJ...So we may not be able to get a good view on long term risk of vaccines...Also CoViD-infections in vaccinated may make a realistic view "hard"...The bizarre contracts the US, UK, Canada, Australia signed with Moderna-making Moderna vaccines the ONLY !!! vaccines used against CoViD for the coming 7 to 10 years makes me wonder if it is a maximum profit operation... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: January 14 2023 at 9:23pm
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DJ, In the strategy to deal with pandemics communication-experts could have done a good job. What-in the communication-totally derailed was the (lack of) discussion on vaccines. Between black and white there are over 50 shades of grey... Some good expert-epidemiologists make the claim that vaccines saved millions of lives. I am NOT an expert-just trying to make up my mind on if I had to go for a vaccine or booster... Other medical experts make the claim (m-RNA) vaccines are much more a risk then the vaccine producers claim. Also m-RNA vaccines would be "gene-therapy" [url]https://en.wikipedia.org/wiki/Gene_therapy[/url] or https://en.wikipedia.org/wiki/Gene_therapy - https://en.wikipedia.org/wiki/Gene_therapy ...well maybe they are-but if they offer protection, "do good" ? Again-I do not know if the name "gene therapy" describes [url]https://en.wikipedia.org/wiki/MRNA_vaccine[/url] or https://en.wikipedia.org/wiki/MRNA_vaccine - https://en.wikipedia.org/wiki/MRNA_vaccine "job"....I follow "the experts"... There have been claims on [url]https://en.wikipedia.org/wiki/Myocarditis#Vaccination[/url] or https://en.wikipedia.org/wiki/Myocarditis#Vaccination - https://en.wikipedia.org/wiki/Myocarditis#Vaccination ;
DJ, some studies claim 1 in 800 vaccinations result in myocarditis...so vaccinating 8 million people would result in 10,000 cases of myocarditis/pericarditis-hearthissues... However... In 2013, about 1.5 million cases of acute myocarditis occurred. https://en.wikipedia.org/wiki/Myocarditis#cite_note-6" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [6] While people of all ages are affected, the young are most often affected. https://en.wikipedia.org/wiki/Myocarditis#cite_note-7" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [7] It is slightly more common in males than females. https://en.wikipedia.org/wiki/Myocarditis#cite_note-NEJM2009-1" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [1] Most cases are mild. https://en.wikipedia.org/wiki/Myocarditis#cite_note-Kin2012-2" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [2] In 2015 https://en.wikipedia.org/wiki/Cardiomyopathy" style="text-decoration: none; color: rgb(6, 69, 173); background: none rgb(255, 255, 255); font-family: sans-serif; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px;" title="Cardiomyopathy - cardiomyopathy , including myocarditis, resulted in 354,000 deaths up from 294,000 in 1990. https://en.wikipedia.org/wiki/Myocarditis#cite_note-GDB2013-8" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [8] https://en.wikipedia.org/wiki/Myocarditis#cite_note-GBD2015De-5" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [5] The initial descriptions of the condition are from the mid-1800s. https://en.wikipedia.org/wiki/Myocarditis#cite_note-9" style="text-decoration: none; color: rgb(6, 69, 173); background: none; - [9] so, a lot of the hearthissues may NOT be related to vaccines at all... say-1% of the vaccine related myocarditis cases are "major" then out of the 8 million vaccinated-10,000 myocarditis cases you end up with 1% is 100 major myocarditis cases ? Every 80,000 given vaccines is 1 major myocarditis case-just as an example-I do not know the "most correct" numbers...Such a number may be higher then expected based on the info the vaccine producers came up with...There may also be allergic reactions to the vaccine;[url]https://en.wikipedia.org/wiki/MRNA_vaccine#Side_effects[/url] or https://en.wikipedia.org/wiki/MRNA_vaccine#Side_effects - https://en.wikipedia.org/wiki/MRNA_vaccine#Side_effects My view; -Vaccination is medical intervention and never 100% risk-free -Communication on the risks has to be open and transparant...this is NOT the case now -In a major healthcrisis there should NOT be any profits being made out of that crisis...m-RNA vaccine producers make billions in profit while the research was tax-funded... -As far as I am aware only the US did see discussion on mandatory vaccinations...North Korea did not have (much) vaccines...so even there people were NOT forced to take vaccinations...(In Europe there was discussion on mandatory vaccines for HCW-ers, police/army etc. limited groups-and the discussion ended by trade unions making the point of self determination of people..Also most employers wanted to avoid-get out-of that discussion-encourage people to take the vaccine..). -Mass vaccinations with non-sterilizing vaccines; you could still catch the virus-vaccine limits disease-did need a wider (then vaccine-only) strategy. That wider strategy was and is still missing... -The outcome is on the short term maybe vaccines saved millions of lives but also on the longer term -more immune evasion due to vaccines-the vaccine (lack of) strategy may result in new variants that claim much more lives...we did only end up buying time... -New vaccines (oral, nasal) may do a better job-however the "variant soup" could result in "the virus" better able to get around it... So-it is an ongoing story...claims more vaccinated people run MORE risk of catching CoViD could point to [url]https://en.wikipedia.org/wiki/Antibody-dependent_enhancement[/url] or https://en.wikipedia.org/wiki/Antibody-dependent_enhancement - https://en.wikipedia.org/wiki/Antibody-dependent_enhancement the virus using immunity reactions to spread... DJ-I did take five times a m-RNA vaccine and for now it may have kept me-and those around me- safe. Waning/decrease of vaccine immunity means vaccine protection last 4 to 6 months... So...when I get offered another booster I have to make up my mind...Communication-TRUSTED, HONEST !!! communication !!! would be more then welcome...Most people on this globe never did get vaccinated...the m-RNA vaccine is mostly a western countries discussion-for now... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: January 22 2023 at 3:24am
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DJ, There are lots of questions on vaccine-safety.... dr.john campbell [url]https://www.youtube.com/watch?v=OD0na_NZaLM[/url] or https://www.youtube.com/watch?v=OD0na_NZaLM - https://www.youtube.com/watch?v=OD0na_NZaLM on excess deaths; There is a striking difference in how mortality rates in 2022 compare to 2019 at different ages 2.5% higher for ages 75-84 7.8% higher for ages 20-44 In the UK, there have been around 155,300 more deaths from all causes than expected from the start of the pandemic to 6 January 2023 DJ...he then links this story with; The UK government has granted pharmaceutical giant Pfizer a legal indemnity protecting it from being sued, enabling its coronavirus vaccine to be rolled out across the country as early as next week. 16th December 2020 DJ...7,8% more deaths in the age group 20-44 in 2022 compared to 2019-UK may NOT be linked to vaccines...most of that age group in the UK did not get vaccinated-as far as I have info...so that higher number of deaths most likely may be linked to CoViD...not the vaccine... Vaccines-for-profit during a global healthcrisis is "sick"...certainly when vaccine producers-with tax money developing and producing those vaccines-do not have to take responsibility for their product.... But that are two different stories.... Prof Shmuel C. Shapira MD MPH, head of the Israel Institute for Biological Research for 8 years, on being vaccinated for Covid three times. “I was wrong 3 times: * Taking the first mRNA shot * Taking the second mRNA shot * And again taking the third mRNA shot. Unfortunately, irreversible mistakes.” DJ...without further info this is a "non-story"... YES-there are risks in using non-sterilizing vaccines. They will result in more immune evasion by mutation-selection... YES-there may be limits to what protection vaccines can offer to new variants better in evading immunity the question is how safe/unsafe the (mRNA) vaccines were/are...? Did Pfizer, Moderna provide all needed info ? (My impression=no...) Are there some groups at higher risk for vaccine complications (young men-hearth issues ?) ...looks like it... DJ-I do NOT have the knowledge to make judgements...I did get vaccinated 5 times...hope it was "wise"...can not undo it...But IF there are risks better stay informed on it... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: March 21 2023 at 11:11pm
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Is there a Link between the 2021 COVID-19 Vaccination Uptake in Europe and 2022 Excess All-Cause Mortality? https://www.youtube.com/redirect?event=video_description&redir_token=QUFFLUhqbmpKdDd1T1FFU2dNcnRjTkNFa0o0REJiSlVjd3xBQ3Jtc0tsMVVmeEV2TE1nY24xNC1TYWhoNnVENUdtVklQaWgtcUZPa3VYVzlxTDBXWDhsMHU3bXNrQjhpczluR3gwMjIwVGlGNmI3eTItVHNMalMyR25DRFBETVFSMjJhaWdFMXBwR3lLNzQ3VXJGOUFIWm9zUQ&q=https%3A%2F%2Fwww.preprints.org%2Fmanuscript%2F202302.0350%2Fv1&v=iyo2UNQcdpQ" rel="nofollow" style="text-decoration: none; display: inline; color: inherit;" tabindex="0 - https://www.preprints.org/manuscript/... (Western Norway University of Applied Sciences). The interaction between vaccination up- take and time passed in months since the beginning of 2022 is strongly significant and implies that the mortality increases the higher the vaccination uptake. Potential reverse causality Could the excess mortality have caused the increase in vaccinations? Concerning alternative explanations We controlled for average all-cause mortality in 2020 and 2021, divided by the average between 2016 and 2019 Relatively low mortality at one period is followed by relatively high mortality later, and vice versa. We still observed a significant association between 2021 vaccination uptake and the 2022 monthly increase in all-cause mortality. DJ, I did take CoViD vaccines 5 times...So the outcome of this study does NOT make me happy...(It is not peer-reviewed...however some basic (Eurostat) numbers only offer limited room - how safe are the vaccines ?) A reason why most vaccinations are stopped is "because the pandemic is over"....Maybe the acute peak of the pandemic is over...we stopped testing... And -I am NOT any kind of expert !- maybe vaccines "limited" the harm CoViD could do ???? There were "anti-vax" claims people dropping dead when the needle of the vaccination was pulled out...Maybe someone had a hearthissue or so....but in general "the idea" is/was vaccines offer protection...If you still catch CoViD it will be "less severe".... Dr.J.C. earlier made claims 1-in 800- vaccinations had (serious) side effects...and that is a lot... I may be offered another booster....will have to make up my mind then.... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: KiwiMum
Date Posted: March 22 2023 at 10:19pm
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I was talking to an ambulance paramedic last Saturday and I asked her how things were work-wise. She told me that for the last 18 months they have been rushed off their feet with the number of call outs going through the roof. I asked her why that was and she said I have no idea. So I asked her if she had noticed an uptick in the number of heart attacks, and she said YES! the numbers are through the roof and that seems to be what all the extra call outs are for. I asked her if she thought this was vaccine related and she said she had no idea, and she said it in such a way as if to suggest she'd never even considered the link between the covid vaccines and the increased number of heart attacks. ------------- Those who got it wrong, for whatever reason, may feel defensive and retrench into a position that doesn’t accord with the facts. |
Posted By: Dutch Josh
Date Posted: March 22 2023 at 11:05pm
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I think the "discussion" on vaccines became something of almost a "religious conflict"....Hardly possible to say "nothing can be 100% perfect".... The idea is vaccines offer protection-at limited risk. So their is a larger benefit then risk "ratio".....There was an urge to develop vaccines at "warp speed"...taking several steps in the procedure at the same time-not the one after the other... Could it be possible something went wrong in that procedure ? Longer term risks of vaccines may be higher then first studies indicated ? ------- Another factor is finance...Why make profits out of a major global crisis ? Profits can "live their own life"...become their own goal..."Big Pharma" has a bad reputation..The idea was government supervision should control Big Pharma...but governments/politics believed "vaccines would save profits (the economy...)"... --------------- In 2003 we stopped SARS-1 by Non Pharma in time Intervention...In 2020 even during the Wuhan lockdown risks were ignored...Governments wanted the WHO "to take the responsibility" for hard decissions...The WHO -political- was not in such a position...So we did NOT stop this pandemic in time...(And the US is agressively pushing "China did it"...ignoring CoViD-19 spread around the globe even early 2019...Lots of cases-likely even before october 2019-in many places OUTSIDE !!!! China... -------- So what to think about vaccines ???? Are they of an increased risk for some groups-still offer protection for lots of others ? Again-I had 5 vaccines...still around...so are most of my family... When a family member test positive for CoViD -so far- disease is limited...with or without vaccination...(But some other contacts died...before vaccines showed up...). ---------- What is needed is good studies to restore trust in the politic-medical intervention idea...People make mistakes-lots of them...In a crisis they may make wrong decissions...turn out to be okay for the short term but get confronted with lots of "complications" in the longer term...Denial only makes matters worse... Statistics on if vaccines are linked with hearth/health issues on the longer term is NOT "high tech"...it is very basic...Dr.J.C. mentioned complications in 1 out of 800 vaccinations...If that number is correct that is a lot of complications...! Do the risks justify taking those risks ? Was CovID itself that "big a risk" ? Maybe if it was-did vaccines do enough to reduce those risks ? Long term Non Pharma Interventions may also NOT be risk-free...(allthough immunity debt is non-science)...masks however are of limited risk, travel decrease have lots of benefits (not only limiting diseases flying allover the planet...it could have slowed down climate collapse...). There are lots of benefits in study/work from home...It would make working/study possible for larger groups...reduce (urban) traffic... So-even if you go for FALSE pandemic now endemic non-sense we should have learnt something from the pandemic...but even that seems to be to optimistic... ----------- DJ-Vaccines are just one tool out of a variety of instruments for intervention in a healthcrisis...I think NPI Non Pharma Intervention may offer much more, faster and at lower costs...Countries we keep/kept poor can go for NPI... Sequencing, testing (waste water) of all kinds of health risks is basic...we are not even doing that... "Can 't fix stupid-even if stupid is killing us all"..... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: March 25 2023 at 3:24am
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DJ, Some ??? with this story; https://twitter.com/CoronaHeadsUp" style="cursor: pointer; background-color: rgba(0, 0, 0, 0); color: inherit; font: inherit; list-style: none; margin: 0px; text-align: inherit; text-decoration: none; -webkit-box-align: stretch; -webkit-box-direction: normal; -webkit-box-orient: vertical; align-items: stretch; border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; min-height: 0px; min-width: 0px; padding: 0px; position: relative; z-index: 0; max-width: 100%; outline-style: none; - https://twitter.com/CoronaHeadsUp" style="cursor: pointer; background-color: rgba(0, 0, 0, 0); color: inherit; font: inherit; list-style: none; margin: 0px; text-align: inherit; text-decoration: none; -webkit-box-align: stretch; -webkit-box-direction: normal; -webkit-box-orient: vertical; align-items: stretch; border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; min-height: 0px; min-width: 0px; padding: 0px; position: relative; z-index: 0; max-width: 100%; outline-style: none;" tabindex="-1 - Covid-19 vaccines affecting the gut microbiome - bifidobacteria wiped out. One of the most alarming things we have heard during the entire pandemic. -  Dr. Sabine Hazan on the Alarming Damage Observed in GI Bacteria Post-Vaccination "Their bifidobacteria dropped to like zero—from like a million to like zero...There was a persistence in the damage, not only 90 days but 6-9 months later." @JanJekielek @SabinehazanMDIf vaccines do that much damage to the guts function it would show up much more..."the epoch times" may not be a medium worth mentioning... https://twitter.com/susan86904619" style="cursor: pointer; background-color: rgba(0, 0, 0, 0); color: inherit; font: inherit; list-style: none; margin: 0px; text-align: inherit; text-decoration: none; -webkit-box-align: stretch; -webkit-box-direction: normal; -webkit-box-orient: vertical; align-items: stretch; border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; min-height: 0px; min-width: 0px; padding: 0px; position: relative; z-index: 0; max-width: 100%; outline-style: none; - https://twitter.com/susan86904619" style="cursor: pointer; background-color: rgba(0, 0, 0, 0); color: inherit; font: inherit; list-style: none; margin: 0px; text-align: inherit; text-decoration: none; -webkit-box-align: stretch; -webkit-box-direction: normal; -webkit-box-orient: vertical; align-items: stretch; border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; min-height: 0px; min-width: 0px; padding: 0px; position: relative; z-index: 0; max-width: 100%; outline-style: none;" tabindex="-1 - Is this why my niece, since immediately after getting the vax has bouts of vomiting that last for more than 14 days, until she ends up in ER for dehydration? It’s happened 4 times this year, her dr told her it’s because she smoked weed when she was a teenager. She’s 21 now  and https://twitter.com/SabinehazanMD" style="cursor: pointer; background-color: rgba(0, 0, 0, 0); color: inherit; font: inherit; list-style: none; margin: 0px; text-align: inherit; text-decoration: none; -webkit-box-align: stretch; -webkit-box-direction: normal; -webkit-box-orient: vertical; align-items: stretch; border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; min-height: 0px; min-width: 0px; padding: 0px; position: relative; z-index: 0; max-width: 100%; outline-style: none; - https://twitter.com/SabinehazanMD" style="cursor: pointer; background-color: rgba(0, 0, 0, 0); color: inherit; font: inherit; list-style: none; margin: 0px; text-align: inherit; text-decoration: none; -webkit-box-align: stretch; -webkit-box-direction: normal; -webkit-box-orient: vertical; align-items: stretch; border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; min-height: 0px; min-width: 0px; padding: 0px; position: relative; z-index: 0; max-width: 100%; outline-style: none;" tabindex="-1 - Yes most likely secondary to EBV that entered or woke up as bif was killed. Test her EBV by blood . Ebv can cause gastroparesis which causes the vomiting. The thread goes on linking vaccines with autism etc. But maybe in some cases vaccines can harm gut-bacteria ??? ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: judeusx
Date Posted: April 27 2023 at 1:30pm
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Raw milk from "bovine covid" vaccinated cows ( is traditional vaccine,almost all cows get it since 30 years,nothing to do with covid -19 ) is one of the best remedies for long covid,and the stomach issue. ( from a long covid suffering doctor: Here is what made the difference |
Posted By: judeusx
Date Posted: April 27 2023 at 2:10pm
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Dont treat covid like the flu,its not over for a long time.Every re-infection heightens your chances of getting long covid.Omicron is much less harmfull then the older variants . "Spike in the vaxxes STILL has PRRAR Furin Cleavage Site (and Nuclear translocation signal) - Omicron lost this." Immune system of the vaccinated is often ruined,so every other infection goes rampant. Thats why we see so much diseases coming back,sometimes under other names. The gut biome is destroyed. And now we get the merging of old type covid-19 reservoirs in animals with H5N1..... |
Posted By: Dutch Josh
Date Posted: May 18 2023 at 3:39am
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To paraphrase, it was basically “If we want to minimize the number of injections when vaccinating a dog, can we mix rabies and ‘core’ (distemper, parvovirus, adenovirus) vaccines, using rabies vaccine as the diluent for the core vaccine?” The idea is that some animals are hard to inject once, let alone twice. Mixing two vaccines into one syringe would make it a one-shot deal, which has appeal. However, are there potential downsides?
Rabies vaccine is a killed vaccine. “Core” vaccines are infectious (modified live) vaccines. For infectious vaccines to work, the modified (weakened) viruses must still be able to cause a low grade infection, to induce an immune response. If rabies vaccine was added, I have no idea what would happen to the modified live organisms. I think it’s plausible that components of the rabies vaccine (which are not designed to support microbial growth and may contain preservatives to inhibit microbes) could inhibit the core vaccine. So, I wouldn’t have confidence that the core vaccine would work as expected.
If we (vets) use a product in a manner not according to the label, we’re getting into unknown territory and creating risk. One consideration is whether the owner would be told that we’re doing something that might inhibit the vaccine(s) from working. We can’t state with confidence that what we’re doing (and charging for) is likely to be effective. From a regulatory standpoint, the bigger issue is rabies vaccine. The expectation is that we are giving rabies vaccine as per the label. If we don’t but we indicate that the animal is properly vaccinate, that’s potentially dodgy. A rabies certificate wouldn’t likely be valid and if the animal was exposed to rabies, it’s far from guaranteed that it would be considered properly vaccinated. (And, if it’s not considered adequately vaccinated, there can be significant quarantine issues). So, while I completely get the desire to limit the number of injections, doing something like mixing vaccines in the same vial or needle is something I’d stay away from. For cats, there’s an easier solution. There’s a licensed vaccine that includes feline core vaccines and rabies vaccine. For dogs, if we want to give multiple vaccines, we need to give multiple injections. DJ, Saving costs may end up combining vaccines in high risk population. This is not risk-free.... There is still discussion on a combination of flu and CoViD vaccines...some want to keep that two weeks apart...Vulnerable people may see a strong reaction of getting vaccinated...however the idea of getting a vaccine also can bring stress (and maybe transport risks, getting infected waiting for vaccination is not welcome !). ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: May 22 2023 at 9:14am
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Three weeks ago, in https://afludiary.blogspot.com/2023/04/cdc-nowcast-recombinants-rule.html" style="text-decoration: none; color: rgb(63, 63, 127); - CDC Nowcast: Recombinants Rule , we looked at the near total domination of emerging XBB.*.* (recombinant) SARS-CoV-2 variants in the United States. Remarkable, because a little over a year ago, there was still scientific debate over their very existence (see https://afludiary.blogspot.com/2022/02/a-covid-recombination-review.html" style="text-decoration: none; color: rgb(0, 127, 127); - A COVID Recombination).
All of the COVID vaccines currently used around the world are either based on either the original 2020 strain - or are bivalent vaccines with an added BA.1 or BA.4/BA.5 component - all of which are pretty much extinct in the wild today. (Full disclosure: Since existing vaccines may still protect against severe illness, I elected to get my 2nd bivalent booster earlier this month).
Yesterday the World Health Organization released the results of a consultation of their Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) which recommends - based on limited data - to a switch to a monovalent vaccine based on XBB.1.5 or XBB.1.6.
There are no guarantees that XBB.1.5/1.6 will still reign supreme 3 or 6 months from now, there is little direct evidence of the effectiveness of XBB derived vaccines in humans, and the willingness of the public to embrace yet another vaccine is unknown. DJ, some will claim a booster-even for variants not around likely several months from now-will increase protection. Maybe it will... Should we not do more to reduce spread of all kinds of diseases ? Why do we promote flying around the globe when that at least is part of the reason why we had the CoViD pandemic to begin with ? Do we offer human H5-infections free travel because we fail to detect them in time ? Should we not at least limit mass events, use masks more ? A legal right to work/study from home ? Did we not even learn vacccines may result in more vaccine-immunity evasion ? Are we simply unwilling to learn anything ? ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: May 22 2023 at 11:59pm
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DJ-The vaccine discussion is "complex"...Vaccines did do many very good things in the past...However non-sterilizing vaccines during a pandemic-and with Non Pharma Interventions being ignored-can make pandemics worse... For the past two decades the World Organization for Animal Health ( https://www.woah.org/" style="text-decoration: none; color: rgb(63, 63, 127); - WOAH , formerly the OIE) has stated that the `preferred' method for dealing with HPAI H5 or H7 in poultry is stamping out (culling), and that vaccines should be viewed as a `temporary' solution at best.
In 2009's https://www.woah.org/en/avian-influenza-and-vaccination-what-is-the-scientific-recommendation-the-oie-repeats-critical-requisites-for-best-use-of-vaccination-in-birds-and-for-a-systematic-exit-strategy/" style="text-decoration: none; color: rgb(63, 63, 127); font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 16px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; background-color: rgb(235, 237, 236); - Avian influenza and vaccination: what is the scientific recommendation?, the OIE reiterated their strong recommendation that humane culling be employed to control avian influenza, and advising that vaccines should only be used as a temporary measure, stating that:
While most of the world's countries followed that advice, http://www.ncbi.nlm.nih.gov/pubmed/23402099" style="text-decoration: none; color: rgb(63, 63, 127); font-weight: bold; - China, Egypt, Indonesia, Vietnam, and Hong Kong - all hotbeds of avian influenza since the early-to-mid 2000s - embraced poultry vaccination instead, with no signs of an `exit strategy'. In theory, a comprehensively applied, and frequently updated poultry vaccination program should be an effective strategy against avian flu, at least in captive birds. But in actual practice (see http://afludiary.blogspot.com/2012/12/egypt-paltry-poultry-vaccine.html" style="text-decoration: none; color: rgb(63, 63, 127); - Egypt: A Paltry Poultry Vaccine) , those can be difficult standards to maintain. Instead we've seen dozens of cautionary studies suggesting that improper application, or outdated vaccines have helped to drive the evolution of avian influenza viruses. A few examples include:
http://wwwnc.cdc.gov/eid/article/20/12/14-0733_article" style="text-decoration: none; color: rgb(63, 63, 127); - Subclinical Highly Pathogenic Avian Influenza Virus Infection among Vaccinated Chickens, China . http://afludiary.blogspot.com/2015/03/study-recombinant-h5n2-avian-influenza.html" style="text-decoration: none; color: rgb(63, 63, 127); - Study: Recombinant H5N2 Avian Influenza Virus Strains In Vaccinated Chickens http://afludiary.blogspot.com/2014/11/eid-journal-subclinical-hpai-in.html" style="text-decoration: none; color: rgb(63, 63, 127); - EID Journal: Subclinical HPAI In Vaccinated Poultry – China In 2013, following the surprise emergence of H7N9 in China (which is asymptomatic in birds, but can be deadly in humans), the OIE softened the language in http://www.oie.int/en/for-the-media/press-releases/detail/article/questions-and-answers-on-influenza-ah7n9/" style="text-decoration: none; color: rgb(63, 63, 127); - their recommendations to allow: 'In short, vaccination should be implemented when culling policies cannot be applied either because the disease is endemic and therefore widely present, or the infection in affected animals is too difficult to detect.' Fast forward another decade and the global avian flu situation has changed radically once again. Prior to 2016, H5N1 was primarily a disease of poultry and had trouble maintaining itself for very long in wild and migratory birds (see https://afludiary.blogspot.com/2016/07/pnas-enigma-of-disappearing-hpai-h5-in.html" style="text-decoration: none; color: rgb(63, 63, 127); - PNAS: The Enigma Of Disappearing HPAI H5 In North American Migratory Waterfowl ), limiting its ability to spread.
Over the past 7 years, https://afludiary.blogspot.com/2022/07/defra-unprecedented-order-shift-in-wild.html" style="text-decoration: none; color: rgb(63, 63, 127); font-family: Arial, Tahoma, Helvetica, FreeSans, sans-serif; font-size: 16px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; background-color: rgb(235, 237, 236); - those host adaptations have only grown stronger.
We've already seen a number of countries move towards poultry vaccination in recent months ( https://afludiary.blogspot.com/2023/03/wur-2-of-4-h5-poultry-vaccines-tested.html" style="text-decoration: none; color: rgb(63, 63, 127); - WUR: 2 of 4 H5 Poultry Vaccines Tested Appear Effective Against H5N1 ), and this week WOAH will meet in Paris at their https://www.woah.org/en/event/90th-general-session-of-the-world-assembly-of-delegates/#ui-id-2" style="text-decoration: none; color: rgb(63, 63, 127); - 90th General Session of the World Assembly of Delegates to discuss how to approach avian influenza prevention and control methods going forward. DJ, H5N1, CoViD both are spreading in "the wild" in mammals...It WILL !!! result in new variants with increased risks for humans !!! We have to prepare for that NOW !!!! -Increase testing/sequencing; surveilance so we may have an idea of what may be coming...But we are NOT doing it !!! -Non Pharma Interventions; from masks, ventialation to limiting travel can slow down the spread of diseases...NOT doing it ! -Good, honest communication, information, discussion...We see claims "CoViD is over"...ignoring hundreds of millions of cases of Long/Chronic CoViD (wich STILL is CoViD !!!) So...at best vaccines may limit disease for a short while at the price of more immunity evasion/new variants and spread in new hosts at the longer term... Fighting pandemics only using non-sterilizing vaccines against CoViD, H5/H7 etc. is POINTLESS !!! It does NOT stop the pandemics...at best may buy us time...we then waste on wars... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: July 02 2023 at 8:42pm
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A growing group of Dutch children have not received the standard vaccinations against infectious diseases. For the first time in decades, the vaccination rate of the youngest age group was slightly below 90 percent last year, reported the National Institute for Public Health and the Environment (RIVM). The institute is concerned about this trend. State Secretary Maarten van Ooijen (Public Health) also called it “really worrying.” “A high vaccination rate is essential to continue to protect people against serious diseases and to prevent outbreaks of these diseases,” the RIVM stressed. There has now been a decline for two years in a row. Jeanne Marie Hament, manager of the National Immunization Program (RVP), hopes the trend can be reversed. Otherwise, there is a threat of “health inequality” between people who have and have not been vaccinated, she said. The RIVM thinks that the decrease may be related to the coronavirus pandemic and the mistrust that some developed against vaccines or the government in general. Van Ooijen also pointed to “disinformation” that circulated during the pandemic years. DJ, my view; -Communication on (CoViD)vaccines was "poor"...mandatory vaccines result in more resistance... -In the CoViD "strategy" to much of the offers were pushed to the individual...air travel opening up, "saving profits/economy" was the political priority... -Non sterilizing vaccines (at best) limit infection/disease but do NOT stop infection...in the "discussion (that was not there) " that part of the non-sterilizing vaccines was ignored.. -Making vaccines/masks etc. "political" is very unwise...(in the US a mask became a political statement....) Outcome; CoViD may decrease immunity against lots of diseases-also in new borns. A decrease in vaccination (measles a.o.) will worsen public health further...Money for large vaccination campains (in the west) may become a problem soon...So that will further worsen the picture... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: October 02 2023 at 11:31pm
These statements were not pro-vaccine. They were pro-stop-worrying-about-COVID.I fully recognize that this is all written with the benefit of https://www.investopedia.com/terms/h/hindsight-bias.asp#:~:text=Hindsight%20bias%20is%20a%20psychological,can%20accurately%20predict%20other%20events." style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - hindsight , but the vaccines did not turn out to be the miracle-cure-all we hoped they would be. According to one https://www.kff.org/policy-watch/why-do-vaccinated-people-represent-most-covid-19-deaths-right-now/" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - article from KFF in November 2022:
Someone who received only the first 2 mRNA vaccine doses in early 2021 might as well be unvaccinated today, and the Johnson and Johnson vaccine, is https://www.cnn.com/2023/05/15/health/johnson-johnson-covid-vaccine-end/index.html#:~:text=The%20Covid%2D19%20vaccine%20from,for%20Disease%20Control%20and%20Prevention." style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - officially a historical relic, unavailable in the US. Meanwhile, the vaccine’s impact on transmission has fluctuated throughout the pandemic, but it has often been https://www.ucsf.edu/news/2022/12/424546/covid-19-vaccines-prior-infection-reduce-transmission-omicron" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - middling at best . Until better vaccines arrive, I will always mask at work. Assurances the vaccines were “100% effective against protecting against bad outcomes for grandparent” and that they lowered the risk of transmission to “zero” were not pro-vaccine. These were pro-stop-worrying-about-COVID. At the start of 2021, these same doctors also claimed the end of the pandemic was imminent. DJ...it looks like newer variants may do better in evading (vaccine) immunity... Non Pharma Interventions NPI-masks, ventilation, rights to work/study from home, limiting travel and mass events, may do a better job than vaccines...We need however a (healthy) combination of both ! Most of all we need to de-"politicize" the public health debate...Virusses do "not work for biden"...Masks are not only for US "democrats"...the US "political insanity" has become a problem for most of the west...(in part paid for from some US elite...). No vaccine is 100% effective or safe, and being pro-vaccine means acknowledging their https://sciencebasedmedicine.org/covid-19-and-balancing-the-risks-the-vaccine-or-the-virus/" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - blemishes and areas of uncertainty, at least with new vaccines. When the original COVID mRNA vaccine data was announced ( https://www.nejm.org/doi/full/10.1056/nejmoa2034577" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - here and https://www.nejm.org/doi/full/10.1056/nejmoa2035389" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - here ), they were 95% effective against COVID infection and even better against severe disease, though https://www.nejm.org/doi/full/10.1056/nejmoa2034577" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - not 100% effective as several doctors claimed. There was a lot to be positive about, and it was vital to convey this information to the public. I encouraged vaccination with every patient I saw, and I still do. Countless people are alive today because doctors properly extolled the benefits of the COVID vaccines. While optimism was entirely appropriate in early 2021, so was caution and humility. The virus was just a just year old, and January 2021 was the deadliest part of the pandemic. Over https://ourworldindata.org/covid-deaths" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - 3,000 Americans died on some days that month. The virus had given us many reasons to respect it in that first year, and we didn’t know what variants might be on the horizon. The vaccines, of course, were brand new. Only 36,930 people had been vaccinated in the two mRNA trials, and they lasted just several months. The median age was 52-years, and trial participants are often unrepresentative of the public at large. There were just 347 cases of COVID, 40 severe cases, and only 1 COVID death in these trials. DJ...in this world NOTHING is 100% perfect ! The pattern isn’t that hard to spot. These doctors wanted us to stop “living in fear” and were willing to overhype brand new vaccines to pacify their audience. Unfortunately, the Delta and Omicron variants arrived and more Americans died of COVID after these podcasts and articles then before them. Yet today, many of these same doctors actively https://vinayprasadmdmph.substack.com/p/no-more-covid-19-shots-without-evidence" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - Despite their flaws, COVID vaccines are the greatest medical achievement of my lifetime, and in an update to this article, https://www.theguardian.com/science/2023/oct/02/scientists-whose-work-enabled-mrna-covid-vaccine-win-nobel-prize-for-medicine-katalin-kariko-drew-weissman" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - Drs. Katalin Karikó and Drew Weissman deservedly won the Nobel Prize for their research. They have already have saved many https://www.cidrap.umn.edu/covid-19/report-covid-19-vaccines-saved-us-115-trillion-3-million-lives" style="box-sizing: border-box; border-width: 0px 0px 2px; border-top-style: initial; border-right-style: initial; border-bottom-style: solid; border-left-style: initial; border-top-color: initial; border-right-color: initial; border-bottom-color: rgb(196, 209, 224); border-left-color: initial; border-image: initial; font-family: inherit; font-size: 19px; font-style: inherit; font-weight: inherit; margin: 0px; outline: 0px; padding: 0px; vertical-align: baseline; color: rgb(39, 109, 202); text-decoration: none; transition: all 0.2s ease-in-out 0s; - millions of people from death and serious suffering. Because I still support them unambiguously and publicly, I often receive hostile feedback from distrustful people who feel they were oversold initially. I get where they are coming from. While their anger may be mistargeted, it is totally understandable. DJ, vaccines should NOT be used for crowd control ! ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: December 30 2023 at 1:30am
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https://twitter.com/EricTopol" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%; - https://twitter.com/EricTopol" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%;" tabindex="-1 - https://twitter.com/EricTopol" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%; - https://twitter.com/EricTopol" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%;" tabindex="-1 - DJ, my non-expert view; vaccines only are part of a pandemic-strategy. Certainly a very hard to control virus like the corona/SARS-2/CoViD virus needs much more than non-sterilizing vaccines ! https://twitter.com/Marc_Veld" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%; - https://twitter.com/Marc_Veld" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%;" tabindex="-1 - - The authors state that previous infections were not taken into account. The groups are a mix of prior immunity. There are no immune naive, or these are a small fraction. Therefore, do not interpret this as previous vaccines did not help! That is incorrect. 4/5 - https://twitter.com/Marc_Veld" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%; - https://twitter.com/Marc_Veld" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%;" tabindex="-1 - A link to the vaccine study [url]https://www.medrxiv.org/content/10.1101/2023.12.24.23300512v1[/url] or https://www.medrxiv.org/content/10.1101/2023.12.24.23300512v1 - https://www.medrxiv.org/content/10.1101/2023.12.24.23300512v1 DJ...again-I am NOT an expert ! My concern is non-sterilizing vaccines and lack of NonPharma Interventions during an ongoing pandemic may result in variants that -at the end- evade ALL immunity...There is only very limited data on non-human CoViD spread (most in mammals) ...if CoViD could be widespread in mice, rats (maybe also pushing up virus particles in waste water ?) most hosts for CoViD would -by now- be non-human... So vaccinating only human hosts with over a hundred species already did see CoViD may indicate another "limit" for vaccines...Maybe some non-human hosts may be "controlled" (minks) a lot of them (mice, rats - also exposed to CoViD via waste water) may be as good as impossible to control... DJ-my view; Dealing with CoViD as if it is "just a flu-like virus" may show to be one of the biggest errors in human history....Vaccines-at least the present ones- did buy us time...We did not use that time to find enough better vaccines..And vaccines are only one of the many tools needed to control a pandemic like this one... -------- https://twitter.com/Marc_Veld" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%; - https://twitter.com/Marc_Veld" style="align-items: stretch; background-color: rgba(0, 0, 0, 0); border: 0px solid black; box-sizing: border-box; display: flex; flex-basis: auto; flex-direction: column; flex-shrink: 1; list-style: none; margin: 0px; min-height: 0px; min-width: 0px; padding: 0px; position: relative; text-decoration: none; z-index: 0; cursor: pointer; outline-style: none; max-width: 100%;" tabindex="-1 - and John Campbell can't process how vaccines are madeDJ a comment; As a nurse (or ex-nurse), John Campbell must have many medically-qualified contacts that he could call up to explain vaccine safety on his show. Instead, he gets a sociologist. It's almost like he's intentionally dishonest for clicks and cash. Weird. I see dr.j.c. as a pro-conservative activist...downplaying the pandemic and anti-vax...Excess deaths statistics indicate vaccines do save lives ! (At least for now !) ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: January 24 2024 at 2:26am
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The Dutch laboratory which investigates the side effects of medicines says there is not enough evidence of a link between coronavirus vaccines and symptoms that are similar to Long Covid and is https://www.lareb.nl/media/g54d3xrc/signals_2024_long-covid-like-symptoms-after-covid-19-vaccination_website.pdf" rel="noopener" style="box-sizing: border-box; color: var(--bs-link-color); text-decoration: underline; - recommending further research . By last August, the lab had received 2,282 reports of long-lasting side effects in people who were vaccinated against coronavirus, of which 78 involved symptoms which are “like those of Long Covid”. “Like Long Covid, these were very diverse” and included breathlessness, tiredness, chest pains, dizziness, muscle ache and brain fog, Lareb said in a new report, published on Wednesday. In total 41 of the 78 patients underwent medical checks and 16 people self-diagnosed their complaints. Eleven people were diagnosed as having Long Covid and three chronic fatigue syndrome. However, the lack of medical research on a large number of the patients means it is impossible to say if their symptoms could have other causes, such as an actual coronavirus diagnosis, Lareb said. In addition, 39 of the patients had previously had coronavirus. “A causal relationship with Covid-19 vaccination cannot be established since potential alternative causes could not be excluded,” Lareb said. “Further epidemiological, clinical and immunological research is needed.” Meanwhile, the health ministry said on Wednesday that just 425 care workers with Long Covid have been awarded €15,000 in extra financial support, even though 806 had registered for the cash. In total, 340 claims were rejected because they were made by people who did not fit the criteria, 37 claims were made too late, and 40 are still being considered, health minister Conny Helder told https://open.overheid.nl/documenten/87559bc5-1487-4b56-9748-17bd4d362ac0/file" style="box-sizing: border-box; color: var(--bs-link-color); text-decoration: underline; - MPs in an update . The government had expected around 1,000 claims. Healthcare workers accounted for a high proportion of infections in the first wave of coronavirus in the spring of 2020, when they were denied proper PPE and exempted from many of the quarantine restrictions so they could keep working. study on what role vaccines could have played in Long CoViD cases...A limited number of people developing Long CoViD symptoms within 28 days after recieving a vaccine...It could mean those people did catch (a/mild-symptomatic) CoViD. It may be hard to exclude CoViD as reason for the Long CoViD symptoms... It is very wise and welcome there are studies on side effects of vaccines but it may be very hard if you can not exclude a covid-infection... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: jandressup
Date Posted: March 22 2024 at 11:55am
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How to I find the complete formulation including all adjuvants of the hepatitis B vaccine? Thanks, Jan ------------- If you have one foot on yesterday...and one foot on tomorrow...You are "piddling" on today!....Take time to smell the Flowers.... |
Posted By: Dutch Josh
Date Posted: March 22 2024 at 10:48pm
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The "rivm" above link has also a link to "bijsluiter" per vaccin... Just a short first reaction after a few minutes with google looking for info on hepatitus-B vaccins... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |
Posted By: Dutch Josh
Date Posted: March 23 2024 at 2:54am
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jandressup- In 2017, a two-dose HBV vaccine for adults, Heplisav-B gained U.S. https://en.wikipedia.org/wiki/Food_and_Drug_Administration" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word;" title="Food and Drug Administration - Food and Drug Administration (FDA) approval. https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-FDA_Heplisav-4" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [4] It uses recombinant HB surface antigen, similar to previous vaccines, but includes a novel CpG 1018 adjuvant, a 22-mer phosphorothioate-linked oligodeoxynucleotide. It was non-inferior with respect to immunogenicity. https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-66" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [66] In November 2021, Hepatitis B Vaccine (Recombinant) (Prehevbrio) was approved by the FDA. https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-FDA_PreHevbrio-7" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [7] https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-67" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [67] https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-68" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [68] https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-69" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [69] Immunization schedule[ https://en.wikipedia.org/w/index.php?title=Hepatitis_B_vaccine&action=edit§ion=11" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; white-space: nowrap;" title="Edit section: Immunization schedule - edit ]The US CDC https://en.wikipedia.org/wiki/Advisory_Committee_on_Immunization_Practices" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word;" title="Advisory Committee on Immunization Practices - ACIP first recommended the vaccine for all newborns in 1991. https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-70" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [70] Prior to this, the vaccine was only recommended for high-risk groups. As of the 1991 recommendation for universal newborn Hepatitis B vaccination, no other vaccines were routinely recommended for all newborns in the United States, and remains one of the very few vaccines routinely recommended for administration at birth. Manufacture[ https://en.wikipedia.org/w/index.php?title=Hepatitis_B_vaccine&action=edit§ion=12" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; white-space: nowrap;" title="Edit section: Manufacture - edit ]The vaccine contains one of the viral envelope https://en.wikipedia.org/wiki/Proteins" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word;" title="Proteins - proteins , Hepatitis B surface antigen ( https://en.wikipedia.org/wiki/HBsAg" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word;" title="HBsAg - HBsAg ). It is produced by yeast cells, into which the gene for HBsAg has been inserted. https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-:5-65" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [65] Afterward an immune system https://en.wikipedia.org/wiki/Antibody" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word;" title="Antibody - antibody to HBsAg is established in the bloodstream. The antibody is known as anti-HBs. This antibody and immune system memory then provide immunity to hepatitis B virus (HBV) infection. https://en.wikipedia.org/wiki/Hepatitis_B_vaccine#cite_note-71" style="text-decoration: none; color: rgb(51, 102, 204); background: none; overflow-wrap: break-word; - [71] -the numbers refer to further wiki-links; I hope it answers part of your question. -There may be several vaccines-each of them may have also info on what is in it on its specific website DJ-I am not any kind of expert...just trying to make some sense... ------------- We cannot solve our problems with the same thinking we used when we created them. ~Albert Einstein |